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Drug Interactions between amoxicillin / clarithromycin / lansoprazole and Tagrisso

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

clarithromycin osimertinib

Applies to: amoxicillin / clarithromycin / lansoprazole and Tagrisso (osimertinib)

Clarithromycin may significantly increase the blood levels of osimertinib. This may increase the risk and/or severity of side effects such as nausea, diarrhea, mouth sores, heart muscle problems (e.G., heart failure), and an irregular heart rhythm that may be serious and potentially life-threatening. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the interaction, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, swelling, or heart palpitations during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

clarithromycin lansoprazole

Applies to: amoxicillin / clarithromycin / lansoprazole and amoxicillin / clarithromycin / lansoprazole

Clarithromycin may increase the blood levels and side effects of lansoprazole in some people. Contact your doctor if you experience diarrhea or other intestinal problems. You may need a dose adjustment if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

amoxicillin clarithromycin

Applies to: amoxicillin / clarithromycin / lansoprazole and amoxicillin / clarithromycin / lansoprazole

Information for this minor interaction is available on the professional version.

Drug and food interactions

Minor

clarithromycin food

Applies to: amoxicillin / clarithromycin / lansoprazole

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer