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Drug Interactions between amoxicillin / clarithromycin / lansoprazole and Plavix

This report displays the potential drug interactions for the following 2 drugs:

  • amoxicillin/clarithromycin/lansoprazole
  • Plavix (clopidogrel)

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Interactions between your drugs

Moderate

clarithromycin lansoprazole

Applies to: amoxicillin / clarithromycin / lansoprazole and amoxicillin / clarithromycin / lansoprazole

Clarithromycin may increase the blood levels and side effects of lansoprazole in some people. Contact your doctor if you experience diarrhea or other intestinal problems. You may need a dose adjustment if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

clarithromycin clopidogrel

Applies to: amoxicillin / clarithromycin / lansoprazole and Plavix (clopidogrel)

Talk to your doctor before using clarithromycin and clopidogrel. This combination may reduce the effects of clopidogrel. Call your doctor promptly if you have any signs of blood clots such as chest pain, shortness of breath, sudden loss of vision, or pain, redness or swelling in an extremity. You may need a dose adjustment or special test if you take both medications. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor.

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Moderate

lansoprazole clopidogrel

Applies to: amoxicillin / clarithromycin / lansoprazole and Plavix (clopidogrel)

Talk to your doctor before using clopidogrel together with lansoprazole. Combining these medications may reduce the effectiveness of clopidogrel in preventing heart attack or stroke. The interaction is most likely to occur if you are using a higher dosage of lansoprazole than recommended or if you are using it too frequently. If you have any concerns, your doctor or pharmacist may be able to offer suggestions on safer alternatives for stomach acid or ulcer while you are being treated with clopidogrel. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

amoxicillin clarithromycin

Applies to: amoxicillin / clarithromycin / lansoprazole and amoxicillin / clarithromycin / lansoprazole

Information for this minor interaction is only available at a professional reading level.

For clinical details see professional interaction data.

Drug and food interactions

Minor

clarithromycin food

Applies to: amoxicillin / clarithromycin / lansoprazole

Information for this minor interaction is only available at a professional reading level.

For clinical details see professional interaction data.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.