Drug Interactions between allopurinol and Kao-Spen
This report displays the potential drug interactions for the following 2 drugs:
- allopurinol
- Kao-Spen (kaolin/pectin)
Interactions between your drugs
allopurinol kaolin
Applies to: allopurinol and Kao-Spen (kaolin/pectin)
ADJUST DOSING INTERVAL: Aluminum-containing oral medications may decrease the absorption of allopurinol and reduce its therapeutic effect. The mechanism of this interaction is unknown; however, it may involve the binding of aluminum to allopurinol in the gastrointestinal tract and preventing its absorption.
MANAGEMENT: Allopurinol should be administered at least 3 hours before or after aluminum-containing medications.
References
- Weissman I, Krivoy N (1987) "Interaction of aluminum hydroxide and allopurinol in patients on chronic hemodialysis." Ann Intern Med, 107, p. 787
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
- Cerner Multum, Inc. "Australian Product Information."
Drug and food interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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