Can you take Actimmune with Influenza virus vaccine, h1n1, live?
1 drug interaction and 7 additional warnings found for the following 2 drugs:
- Actimmune (interferon gamma-1b)
- influenza virus vaccine, h1n1, live
Drug interactions
Moderate drug interactions
Moderate:
interferon gamma-1b influenza virus vaccine, H1N1, live
Applies to: Actimmune (interferon gamma-1b) and influenza virus vaccine, h1n1, live
If you are currently being treated or recently received treatment with interferon gamma-1b, let your doctor know before receiving influenza virus vaccine, H1N1, live. Treatment with interferon gamma-1b may lead to an unexpected or amplified response to the vaccine. In some situations, your doctor may want to delay vaccination. If you have recently been vaccinated with influenza virus vaccine, H1N1, live, your doctor may choose to postpone treatment with interferon gamma-1b for a couple of weeks or more. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Food/lifestyle interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease interactions
7 potential interactions Applies to: 7 conditions, including Heart Failure, Seizures, Arrhythmia, Psychosis, and Parkinsonism.
Arrhythmia
Major:
Actimmune
The interferon gamma-1b in Actimmune has a major potential interaction with Arrhythmia.
Hypertension, arrhythmias, angina, myocardial infarction, cardiomyopathy, and congestive heart failure have been reported during interferon therapy. Therapy with interferons should be administered with caution in patients with compromised cardiac function.
Bone Marrow Depression/Low Blood Counts
Moderate:
Actimmune
The interferon gamma-1b in Actimmune has a moderate potential interaction with Bone Marrow Depression/Low Blood Counts.
Interferons (alfa and gamma) induce a dose-dependent, generally mild, myelosuppression. Leukopenia is the primary manifestation. Thrombocytopenia and anemia occur less frequently. Therapy with interferons (alfa and gamma) should be administered cautiously to patients with bone marrow suppression. Clinical monitoring of hematopoietic function is recommended.
Heart Failure
Major:
Actimmune
The interferon gamma-1b in Actimmune has a major potential interaction with Heart Failure.
Hypertension, arrhythmias, angina, myocardial infarction, cardiomyopathy, and congestive heart failure have been reported during interferon therapy. Therapy with interferons should be administered with caution in patients with compromised cardiac function.
Ischemic Heart Disease
Major:
Actimmune
The interferon gamma-1b in Actimmune has a major potential interaction with Ischemic Heart Disease.
Hypertension, arrhythmias, angina, myocardial infarction, cardiomyopathy, and congestive heart failure have been reported during interferon therapy. Therapy with interferons should be administered with caution in patients with compromised cardiac function.
Parkinsonism
Major:
Actimmune
The interferon gamma-1b in Actimmune has a major potential interaction with Parkinsonism.
Reversible CNS effects such as seizures, mental status changes, manic behavior or psychotic reactions, gait disturbances, and dizziness have occurred in patients receiving interferons. Therapy with interferons should be administered cautiously in patients with or predisposed to seizures, psychiatric disorders, or conditions affecting posture or gait.
Psychosis
Major:
Actimmune
The interferon gamma-1b in Actimmune has a major potential interaction with Psychosis.
Reversible CNS effects such as seizures, mental status changes, manic behavior or psychotic reactions, gait disturbances, and dizziness have occurred in patients receiving interferons. Therapy with interferons should be administered cautiously in patients with or predisposed to seizures, psychiatric disorders, or conditions affecting posture or gait.
Seizures
Major:
Actimmune
The interferon gamma-1b in Actimmune has a major potential interaction with Seizures.
Reversible CNS effects such as seizures, mental status changes, manic behavior or psychotic reactions, gait disturbances, and dizziness have occurred in patients receiving interferons. Therapy with interferons should be administered cautiously in patients with or predisposed to seizures, psychiatric disorders, or conditions affecting posture or gait.
Report options
More resources
Actimmune
A total of 207 drugs are known to interact with Actimmune.
- Actimmune is in the drug class interferons.
- Actimmune is used to treat the following conditions:
influenza virus vaccine, h1n1, live
A total of 445 drugs are known to interact with influenza virus vaccine, h1n1, live.
- Influenza virus vaccine, h1n1, live is in the drug class viral vaccines.
- Influenza virus vaccine, h1n1, live is used to treat the following conditions:
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.