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Drug Interactions between Acid Reducer Plus Antacid and methylprednisolone

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

methylPREDNISolone magnesium hydroxide

Applies to: methylprednisolone and Acid Reducer Plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

Talk to your doctor before using methylPREDNISolone together with any kind of medication that has a laxative effect. Combining these medications, especially over a prolonged period, may increase the risk of dehydration and hypokalemia, or low blood potassium. In severe cases, hypokalemia can lead to muscle weakness, paralysis, breathing and swallowing difficulties (due to muscle paralysis), and irregular heart rhythm. Contact your doctor if you experience nausea, vomiting, dry mouth, thirst, decreased urination, constipation, abdominal cramping, confusion, dizziness, lightheadedness, fainting, muscle weakness, muscle cramps, numbness or tingling, rapid heart beat, chest pain, and/or swelling in the legs or feet, as these may be symptoms of dehydration and hypokalemia. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

famotidine calcium carbonate

Applies to: Acid Reducer Plus Antacid (calcium carbonate / famotidine / magnesium hydroxide) and Acid Reducer Plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

Information for this minor interaction is available on the professional version.

Minor

famotidine magnesium hydroxide

Applies to: Acid Reducer Plus Antacid (calcium carbonate / famotidine / magnesium hydroxide) and Acid Reducer Plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

Information for this minor interaction is available on the professional version.

Minor

methylPREDNISolone calcium carbonate

Applies to: methylprednisolone and Acid Reducer Plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

methylPREDNISolone food

Applies to: methylprednisolone

Grapefruit juice may increase the blood levels of certain medications such as methylPREDNISolone. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with methylPREDNISolone. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

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Moderate

calcium carbonate food

Applies to: Acid Reducer Plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

Calcium absorption may be increased by taking it with food. However, foods high in oxalic acid (spinach or rhubarb), or phytic acid (bran and whole grains) may decrease calcium absorption. Calcium may be taken with food to increase absorption. Consider spacing calcium administration for at least 2 hours before or after consuming foods high in oxalic acid or phytic acid. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

famotidine food

Applies to: Acid Reducer Plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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