Can you take Abenol with Disulfiram?

Disulfiram has a major potential interaction with Acute Alcohol Intoxication.

The administration of disulfiram is contraindicated in patients in a state of alcohol intoxication. The disulfiram- alcohol reaction may produce symptoms including flushing, throbbing in head and neck, throbbing headache, respiratory difficulty, nausea, vomiting, sweating, thirst, chest pain, palpitation, dyspnea, hyperventilation, tachycardia, hypotension, syncope, weakness, vertigo, blurred vision, and confusion. Severe reactions may result in respiratory depression, cardiovascular collapse, arrhythmias, myocardial infarction, acute congestive heart failure, unconsciousness, convulsions, and death.

The acetaminophen in Abenol has a major potential interaction with Alcoholism.

Chronic alcohol abusers may be at increased risk of hepatotoxicity during treatment with acetaminophen (APAP). Severe liver injury, including cases of acute liver failure resulting in liver transplant and death, has been reported in patients using acetaminophen. Therapy with acetaminophen should be administered cautiously, if at all, in patients who consume three or more alcoholic drinks a day. In general, patients should avoid drinking alcohol while taking acetaminophen-containing medications. Patients should be warned not to exceed the maximum recommended total daily dosage of acetaminophen (4 g/day in adults and children 12 years of age or older), and to read all prescription and over-the-counter medication labels to ensure they are not taking multiple acetaminophen-containing products, or check with a healthcare professional if they are unsure. They should also be advised to seek medical attention if they experience signs and symptoms of liver injury such as fever, rash, anorexia, nausea, vomiting, fatigue, right upper quadrant pain, dark urine, and jaundice.

Disulfiram has a major potential interaction with Cardiovascular Conditions and Disorders.

The use of disulfiram is contraindicated in patients with cardiac disease. The potential for a disulfiram- alcohol reaction, symptoms of which can include cardiovascular effects such as palpitation, tachycardia, chest pain, hypotension, syncope and, in severe cases, cardiovascular collapse, arrhythmias, myocardial infarction, and acute congestive heart failure, may present a particular danger to these patients.

The acetaminophen in Abenol has a major potential interaction with Dehydration.

Acetaminophen is contraindicated in patients with severe hepatic impairment or severe active liver disease. Patients with hepatic impairment may be at increased risk of toxicity. Severe liver injury, including cases of acute liver failure and death, have been reported in patients using this drug. Clinical monitoring of hepatic function is recommended. Caution is advised if using acetaminophen in patients with chronic malnutrition or severe hypovolemia. Instruct patients to avoid drinking alcohol while taking acetaminophen-containing medications. Patients should be warned not to exceed the maximum recommended total daily dosage of acetaminophen (4 g/day in adults and children 12 years of age or older), and to read all prescription and over-the-counter medication labels to ensure they are not taking multiple acetaminophen-containing products, or check with a healthcare professional if they are unsure.

Disulfiram has a major potential interaction with Diabetes Mellitus.

The disulfiram- alcohol reaction may produce symptoms including flushing, throbbing in head and neck, throbbing headache, respiratory difficulty, nausea, vomiting, sweating, thirst, chest pain, palpitation, dyspnea, hyperventilation, tachycardia, hypotension, syncope, weakness, vertigo, blurred vision, and confusion. Severe reactions may result in respiratory depression, cardiovascular collapse, arrhythmias, myocardial infarction, acute congestive heart failure, unconsciousness, convulsions, and death. Because of the possibility of an accidental disulfiram- alcohol reaction, disulfiram should be used with extreme caution in patients with diabetes mellitus, hypothyroidism, seizure disorders, cerebral damage, chronic and acute nephritis, hepatic cirrhosis or insufficiency.

Disulfiram has a major potential interaction with Glomerulonephritis.

The disulfiram- alcohol reaction may produce symptoms including flushing, throbbing in head and neck, throbbing headache, respiratory difficulty, nausea, vomiting, sweating, thirst, chest pain, palpitation, dyspnea, hyperventilation, tachycardia, hypotension, syncope, weakness, vertigo, blurred vision, and confusion. Severe reactions may result in respiratory depression, cardiovascular collapse, arrhythmias, myocardial infarction, acute congestive heart failure, unconsciousness, convulsions, and death. Because of the possibility of an accidental disulfiram- alcohol reaction, disulfiram should be used with extreme caution in patients with diabetes mellitus, hypothyroidism, seizure disorders, cerebral damage, chronic and acute nephritis, hepatic cirrhosis or insufficiency.

The acetaminophen in Abenol has a major potential interaction with Liver Disease.

Acetaminophen is contraindicated in patients with severe hepatic impairment or severe active liver disease. Patients with hepatic impairment may be at increased risk of toxicity. Severe liver injury, including cases of acute liver failure and death, have been reported in patients using this drug. Clinical monitoring of hepatic function is recommended. Caution is advised if using acetaminophen in patients with chronic malnutrition or severe hypovolemia. Instruct patients to avoid drinking alcohol while taking acetaminophen-containing medications. Patients should be warned not to exceed the maximum recommended total daily dosage of acetaminophen (4 g/day in adults and children 12 years of age or older), and to read all prescription and over-the-counter medication labels to ensure they are not taking multiple acetaminophen-containing products, or check with a healthcare professional if they are unsure.

Disulfiram has a moderate potential interaction with Liver Disease.

Hepatic toxicity, hepatitis, and hepatic failure resulting in transplantation or death have been reported with the use of disulfiram. Hepatic toxicity has occurred in patient with and without prior history of abnormal liver function. Extreme caution and close monitoring is advised if used in patients with liver impairment. Baseline and liver tests are suggested in all patients to detect any hepatic abnormalities. Patients should be advised to immediately notify their health provider if any symptoms of hepatitis occur (weakness, fatigue, anorexia, nausea, vomiting, jaundice, or dark urine).

The acetaminophen in Abenol has a major potential interaction with Malnourishment.

Acetaminophen is contraindicated in patients with severe hepatic impairment or severe active liver disease. Patients with hepatic impairment may be at increased risk of toxicity. Severe liver injury, including cases of acute liver failure and death, have been reported in patients using this drug. Clinical monitoring of hepatic function is recommended. Caution is advised if using acetaminophen in patients with chronic malnutrition or severe hypovolemia. Instruct patients to avoid drinking alcohol while taking acetaminophen-containing medications. Patients should be warned not to exceed the maximum recommended total daily dosage of acetaminophen (4 g/day in adults and children 12 years of age or older), and to read all prescription and over-the-counter medication labels to ensure they are not taking multiple acetaminophen-containing products, or check with a healthcare professional if they are unsure.

The acetaminophen in Abenol has a moderate potential interaction with Phenylketonuria.

Several oral acetaminophen and acetaminophen-combination products, particularly flavored chewable tablets, contain the artificial sweetener, aspartame (NutraSweet). Aspartame is converted to phenylalanine in the gastrointestinal tract following ingestion. Chewable and effervescent formulations of acetaminophen products may also contain phenylalanine. The aspartame/phenylalanine content should be considered when these products are used in patients who must restrict their intake of phenylalanine (i.e. phenylketonurics).

Disulfiram has a major potential interaction with Psychosis.

The use of disulfiram is contraindicated in patients with psychosis. Disulfiram may precipitate psychotic reactions and mood disorders, particularly when given in high dosages or with metronidazole or isoniazid. In some cases, however, the sudden withdrawal of alcohol alone can unmask underlying psychotic disorders.

Disulfiram has a major potential interaction with Seizures.

The disulfiram- alcohol reaction may produce symptoms including flushing, throbbing in head and neck, throbbing headache, respiratory difficulty, nausea, vomiting, sweating, thirst, chest pain, palpitation, dyspnea, hyperventilation, tachycardia, hypotension, syncope, weakness, vertigo, blurred vision, and confusion. Severe reactions may result in respiratory depression, cardiovascular collapse, arrhythmias, myocardial infarction, acute congestive heart failure, unconsciousness, convulsions, and death. Because of the possibility of an accidental disulfiram- alcohol reaction, disulfiram should be used with extreme caution in patients with diabetes mellitus, hypothyroidism, seizure disorders, cerebral damage, chronic and acute nephritis, hepatic cirrhosis or insufficiency.

Disulfiram has a major potential interaction with Underactive Thyroid.

The disulfiram- alcohol reaction may produce symptoms including flushing, throbbing in head and neck, throbbing headache, respiratory difficulty, nausea, vomiting, sweating, thirst, chest pain, palpitation, dyspnea, hyperventilation, tachycardia, hypotension, syncope, weakness, vertigo, blurred vision, and confusion. Severe reactions may result in respiratory depression, cardiovascular collapse, arrhythmias, myocardial infarction, acute congestive heart failure, unconsciousness, convulsions, and death. Because of the possibility of an accidental disulfiram- alcohol reaction, disulfiram should be used with extreme caution in patients with diabetes mellitus, hypothyroidism, seizure disorders, cerebral damage, chronic and acute nephritis, hepatic cirrhosis or insufficiency.