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Drug Interactions between 12 Hour Cold and Mounjaro

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

pseudoephedrine tirzepatide

Applies to: 12 Hour Cold (dexbrompheniramine / pseudoephedrine) and Mounjaro (tirzepatide)

Pseudoephedrine may interfere with blood glucose control and reduce the effectiveness of tirzepatide and other diabetic medications. Monitor your blood sugar levels closely. You may need a dose adjustment of your diabetic medications during and after treatment with pseudoephedrine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

dexbrompheniramine tirzepatide

Applies to: 12 Hour Cold (dexbrompheniramine / pseudoephedrine) and Mounjaro (tirzepatide)

Tirzepatide can cause an increase in heart rate and may have additive effects with other medications that can also increase heart rate such as dexbrompheniramine. There are times when an elevated heart rate is appropriate, like when you are exercising. However, you should contact your doctor if you notice that your heart rate is high at other times for unknown reasons or if it is occurring frequently. Signs and symptoms of an elevated heart rate may include a sensation of a racing or pounding heartbeat, chest pain, shortness of breath, or a heart rate greater than 100 beats per minute in an adult. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

dexbrompheniramine food

Applies to: 12 Hour Cold (dexbrompheniramine / pseudoephedrine)

Alcohol can increase the nervous system side effects of dexbrompheniramine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with dexbrompheniramine. Do not use more than the recommended dose of dexbrompheniramine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

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Moderate

tirzepatide food

Applies to: Mounjaro (tirzepatide)

Tirzepatide may affect the absorption of other medications that you take by mouth. In some cases, this may affect how well and/or how fast those medications work, or it may make no difference. Talk to a healthcare provider if you have any questions or concerns, and contact your doctor if your symptoms worsen or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

pseudoephedrine food

Applies to: 12 Hour Cold (dexbrompheniramine / pseudoephedrine)

Both pseudoephedrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.