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Nucleoside reverse transcriptase inhibitors (NRTIs)

What are Nucleoside reverse transcriptase inhibitors (NRTIs)?

Nucleoside reverse transcriptase inhibitors (NRTIs) are active inhibitors of reverse transcriptase found in retroviruses such as the human immunodeficiency virus (HIV). The different nucleoside reverse transcriptase inhibitors may be activated differently but they have the same mechanism of action. NRTIs are activated generally by phosphorylation to the triphosphate form by cellular enzymes. It then competes with cellular triphosphates, which are substrates for proviral DNA by viral reverse transcriptase. NRTIs are used in the treatment of human immunodeficiency virus (HIV infection) and acquired immune deficiency syndrome (AIDS).

List of Nucleoside reverse transcriptase inhibitors (NRTIs):

View by  Brand | Generic
Drug Name Reviews Avg. Ratings
adefovir systemic (Pro)
0 reviews
10
entecavir systemic (Pro)
2 reviews
10
telbivudine systemic (Pro)
0 reviews
10
didanosine systemic (Pro)
0 reviews
9.0
tenofovir systemic (Pro)
21 reviews
8.2
tenofovir alafenamide systemic (Pro)
1 review
8.0
lamivudine systemic (Pro)
4 reviews
7.6
zidovudine systemic (Pro)
1 review
5.0
abacavir systemic (Pro)
1 review
4.5
stavudine systemic (Pro)
0 reviews
1.0
emtricitabine systemic (Pro)
0 reviewsAdd rating
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

See Also

Medical conditions associated with nucleoside reverse transcriptase inhibitors (NRTIs):