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Emtricitabine / Rilpivirine / Tenofovir Alafenamide Dosage

Medically reviewed by Drugs.com. Last updated on Feb 16, 2024.

Applies to the following strengths: 200 mg-25 mg-300 mg; 200 mg-25 mg-25 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for HIV Infection

1 tablet orally once a day

Comments:


Use: As a complete regimen for the treatment of HIV-1 infection, as initial therapy in patients with no antiretroviral treatment history with HIV-1 RNA up to 100,000 copies/mL or to replace a stable antiretroviral regimen in patients who are virologically-suppressed (HIV-1 RNA less than 50 copies/mL) for at least 6 months with no history of treatment failure and no known substitutions associated with resistance to the individual components

Usual Pediatric Dose for HIV Infection

At least 35 kg: 1 tablet orally once a day

Comments:


Use: As a complete regimen for the treatment of HIV-1 infection, as initial therapy in patients with no antiretroviral treatment history with HIV-1 RNA up to 100,000 copies/mL or to replace a stable antiretroviral regimen in patients who are virologically-suppressed (HIV-1 RNA less than 50 copies/mL) for at least 6 months with no history of treatment failure and no known substitutions associated with resistance to the individual components

Renal Dose Adjustments

Emtricitabine/rilpivirine/tenofovir alafenamide:


Emtricitabine/rilpivirine/tenofovir disoproxil fumarate (DF):

Liver Dose Adjustments

Mild or moderate liver dysfunction (Child-Pugh A or B): No adjustment recommended.
Severe liver dysfunction (Child-Pugh C): Data not available

Dose Adjustments

Emtricitabine/rilpivirine/tenofovir DF:

Precautions

US BOXED WARNING:


CONTRAINDICATIONS:

Safety and efficacy have not been established in patients weighing less than 35 kg; this drug is not recommended for use in these patients.

Consult WARNINGS section for additional precautions.

Dialysis

Emtricitabine/rilpivirine/tenofovir alafenamide:


Emtricitabine/rilpivirine/tenofovir DF: Not recommended.

Comments (emtricitabine/rilpivirine/tenofovir alafenamide):

Other Comments

Administration advice:


Storage requirements:

General:

Monitoring:

Patient advice:

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Patient resources

Other brands

Odefsey

Professional resources

Other brands

Odefsey

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.