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Proferrin-Forte Disease Interactions

There are 2 disease interactions with Proferrin-Forte (folic acid / heme iron polypeptide).

Major

Ferrous salts (applies to Proferrin-Forte) hemoglobin abnormalities

Major Potential Hazard, Moderate plausibility. Applicable conditions: Blood Transfusion, Hemoglobinopathy

There is no excretory mechanism for iron. Iron will correct only hemoglobin abnormalities due to iron deficiency and should not be used to treat conditions such as thalassemia, hemosiderosis, hemochromatosis, normocytic anemia (unless iron deficiency exists), or in patients receiving blood transfusions. Clinical monitoring of erythropoietic function and ferritin levels is recommended.

References (2)
  1. "Product Information. Infed (iron dextran)." Schein Pharmaceuticals Inc
  2. (2001) "Product Information. Venofer (iron sucrose)." American Regent Laboratories Inc
Major

Folic acid (applies to Proferrin-Forte) anemia

Major Potential Hazard, High plausibility. Applicable conditions: Anemia of Unspecified Nutritional Deficiency

The use of folic acid is contraindicated in patients with undiagnosed anemia. Folic acid in dosages above 1 mg/day can obscure the diagnosis of pernicious anemia by alleviating the hematologic abnormalities while allowing the progression of neurologic complications. In addition, folic acid alone is improper therapy in the treatment of pernicious anemia and other megaloblastic anemias where vitamin B12 is deficient.

References (3)
  1. Butterworth CE Jr, Tamura T (1989) "Folic acid safety and toxicity: a brief review." Am J Clin Nutr, 50, p. 353-8
  2. Katz M (1973) "Potential danger of self-medication with folic acid." N Engl J Med, 289, p. 1095
  3. "Product Information. Renal Multivitamin Formula Rx (folic acid)." Vitaline Corporation, Ashland, OR.

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Proferrin-Forte drug interactions

There are 113 drug interactions with Proferrin-Forte (folic acid / heme iron polypeptide).

Proferrin-Forte alcohol/food interactions

There is 1 alcohol/food interaction with Proferrin-Forte (folic acid / heme iron polypeptide).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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