Hemgenix Disease Interactions
There are 2 disease interactions with Hemgenix (etranacogene dezaparvovec).
Etranacogene dezaparvovec (applies to Hemgenix) hepatic cancer
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Infectious Hepatitis, Liver Disease, Alcoholism
Therapy with etranacogene dezaparvovec may increase the risk of hepatocellular carcinoma development. Patients with preexisting risk factors for hepatocellular cancer such as cirrhosis, advanced hepatic fibrosis, hepatitis B or C, non-alcoholic fatty liver disease, alcoholism, non-alcoholic steatohepatitis, and advanced age should be monitored annually with a liver ultrasound and alpha-fetoprotein testing during 5 years following administration. The safety and efficacy of this drug in patients with severe hepatic impairment has not been studied.
Etranacogene dezaparvovec (applies to Hemgenix) renal dysfunction
Moderate Potential Hazard, Moderate plausibility.
The safety and efficacy of etranacogene dezaparvovec in patients with severe renal impairment and end-stage renal disease have not been studied. Caution is advised.
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Hemgenix drug interactions
There are 295 drug interactions with Hemgenix (etranacogene dezaparvovec).
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- FDA approval history
- Drug class: miscellaneous coagulation modifiers
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Botox
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Idelvion
Idelvion (coagulation factor ix recombinant, albumin fusion protein) is a long-acting, injectable ...
BeneFix
BeneFix (coagulation factor IX) is a once-weekly, injectable, treatment for hemophilia B that may ...
Profilnine
Profilnine is used for factor ix deficiency, factor vii deficiency, hemophilia a with inhibitors ...
Alprolix
Alprolix is used in hemophilia B to help control and prevent bleeding, it is a coagulation Factor ...
NovoSeven RT
NovoSeven RT (coagulation Factor VIIa, recombinant) is an injectable, coagulation factor VIIa that ...
Alphanine SD
Alphanine SD is used for factor ix deficiency, hemophilia b
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
