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Hepatolite Disease Interactions

There is 1 disease interaction with Hepatolite (disofenin).

Moderate

Technetium Tc 99m disofenin/mebrofenin (applies to Hepatolite) gallbladder nonvisualization

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Pancreatitis, Liver Disease, Sepsis, Biliary Obstruction

Nonvisualization or delayed visualization of the gallbladder may occur in certain populations, including patients who have been fasting for a prolonged period or undergoing parenteral feeding; patients with chronic cholecystitis or pancreatitis; and patients with hepatocellular disease or juvenile hepatitis. Septic patients may show absent or delayed hepatobiliary clearance. Therefore, a positive finding does not, by itself, permit a differential diagnosis and should be considered in conjunction with the total clinical picture and results of other diagnostic modalities.

References (1)
  1. (2012) "Product Information. Choletec (mebrofenin)." Bracco Diagnostics Inc

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

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