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Dexamethasone otic Disease Interactions

There is 1 disease interaction with dexamethasone otic:

Major

Otic Corticosteroids (Includes Dexamethasone otic) ↔ Viral Infections

Severe Potential Hazard, High plausibility

Applies to: Herpes Simplex Otitis Externa, Herpes Zoster Otitis Externa

The use of otic preparations containing corticosteroids is contraindicated in patients with viral infections of the external canal including varicella and herpes simplex otitis externa. Corticosteroids may decrease host resistance to infectious agents, thus prolonging the course and/or exacerbating the severity of the infection while encouraging the development of new or secondary infection. Normally, corticosteroids may be administered with caution provided it is accompanied by appropriate anti-infective agents. However, otic preparations that are currently available lack effective antiviral agents.

References

  1. American Medical Association, Division of Drugs and Toxicology "Drug evaluations annual 1994." Chicago, IL: American Medical Association; (1994):

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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