Benzocaine / chloroxylenol topical Disease Interactions
There is 1 disease interaction with benzocaine / chloroxylenol topical:
Benzocaine (applies to benzocaine/chloroxylenol topical) methemoglobinemia
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: G-6-PD Deficiency
Rarely, benzocaine has induced methemoglobinemia resulting in respiratory distress and cyanosis. Therapy with benzocaine should be administered cautiously to patients with or predisposed to methemoglobinemia. If life-threatening or severe methemoglobinemia develops, methylene blue infused at a dosage of 1 to 2 mg/kg body weight will rapidly reverse or improve the condition except in G-6-PD-deficient patients.
- "Product Information. Americaine (benzocaine topical)." Novartis Consumer Health, Summit, NJ.
- "Product Information. Americaine Otic (benzocaine otic)." Medeva Pharmaceuticals, Rochester, NY.
Benzocaine / chloroxylenol topical drug interactions
There are 40 drug interactions with benzocaine / chloroxylenol topical
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|