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Norisodrine with Calcium Iodine (anhydrous calcium iodide / isoproterenol) Disease Interactions

There are 4 disease interactions with Norisodrine with Calcium Iodine (anhydrous calcium iodide / isoproterenol):

Major

Isopreterenol (applies to Norisodrine with Calcium Iodine) tachyarrhythmias

Major Potential Hazard, Moderate plausibility. Applicable conditions: Angina Pectoris

The use of isoproterenol is contraindicated in patients with tachyarrhythmias; tachycardia or heart block caused by digitalis intoxication; ventricular arrhythmias which require inotropic therapy; and angina pectoris.

Major

Sympathomimetics (applies to Norisodrine with Calcium Iodine) dehydration

Major Potential Hazard, High plausibility.

The use of sympathomimetic amines has been infrequently associated with significant hypotension especially in dehydrated patients secondary to the drug's beta-2 mediated vasodilation. Hypovolemia should be corrected, if possible, before administering sympathomimetic amines. Blood pressure and ECG should be monitored at regular intervals. Monitoring of cardiac output and pulmonary wedge pressure may also be desired.

References

  1. "Product Information. Adrenalin Chloride Solution (epinephrine)." Parke-Davis, Morris Plains, NJ.
  2. "Product Information. Epifrin Sterile Ophthalmic Solution (epinephrine)." Allergan Inc, Irvine, CA.
  3. "Product Information. Isuprel (isoproterenol)." Sanofi Winthrop Pharmaceuticals, New York, NY.
  4. "Product Information. Levophed Bitartrate (norepinephrine)." Sanofi Winthrop Pharmaceuticals, New York, NY.
View all 4 references
Moderate

Iodide salts (applies to Norisodrine with Calcium Iodine) hyperthyroidism

Moderate Potential Hazard, Low plausibility.

The use of iodide salts has been associated with the exacerbation or precipitation of hyperthyroidism in patients previously euthyroid. Induction of goiter has been reported in patients with hyperthyroidism. Iodide salts should be administered cautiously in patients with hyperthyroidism.

References

  1. Yalow RS "Risks in mass distribution of potassium iodide." Bull N Y Acad Med 59 (1983): 1020-7
  2. Iancu T, Boyanower Y, Laurian N "Congenital goiter due to maternal ingestion of iodide." Am J Dis Child 128 (1974): 528-30
  3. Ayromlooi J "Congenital goiter due to maternal ingestion of iodides." Obstet Gynecol 39 (1972): 818-22
  4. Denham MJ, Himsworth RL "Hyperthyroidism induced by potassium iodide given in the course of 125I-fibrinogen test." Age Ageing 3 (1974): 221-5
  5. "Product Information. SSKI (potassium iodide)." Upsher-Smith Laboratories Inc, Minneapolis, MN.
  6. Carswell F, Kerr MM, Hutchison JH "Congenital goitre and hypothyroidism produced by maternal ingestion of iodides." Lancet 1 (1970): 1241-3
  7. Parmelle A, et al "Three cases of newborn infants with congential goiter due to ingestion of iodide." Am J Obstet Gynecol 40 (1940): 145-7
  8. "Product Information. Pima Syrup (potassium iodide)." Fleming and Company, Fenton, MO.
View all 8 references
Moderate

Sympathomimetics (applies to Norisodrine with Calcium Iodine) acidosis

Moderate Potential Hazard, High plausibility.

Acidosis, hypoxia, and hypercapnia may reduce the effectiveness of sympathomimetic amines in raising blood pressure. These conditions should be corrected before initiating therapy with sympathomimetic amines, if possible. Monitoring the patients acid-base balance, carbon dioxide levels, and oxygen saturation is recommended.

References

  1. "Product Information. Adrenalin Chloride Solution (epinephrine)." Parke-Davis, Morris Plains, NJ.
  2. "Product Information. Isuprel (isoproterenol)." Sanofi Winthrop Pharmaceuticals, New York, NY.
  3. "Product Information. Epifrin Sterile Ophthalmic Solution (epinephrine)." Allergan Inc, Irvine, CA.
  4. "Product Information. Levophed Bitartrate (norepinephrine)." Sanofi Winthrop Pharmaceuticals, New York, NY.
View all 4 references

Norisodrine with Calcium Iodine (anhydrous calcium iodide / isoproterenol) drug interactions

There are 402 drug interactions with Norisodrine with Calcium Iodine (anhydrous calcium iodide / isoproterenol)

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.