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Albumin aggregated Disease Interactions

There is 1 disease interaction with albumin aggregated:


Technetium Tc 99M Albumin Aggregated (Includes Albumin aggregated) ↔ Pulmonary Heart Disease

Severe Potential Hazard, High plausibility

Applies to: Pulmonary Heart or Vascular Disease

The use of Technetium Tc 99m albumin aggregated injection is contraindicated in patients with severe pulmonary hypertension. There have been reports of death following its administration to patients with preexisting severe pulmonary hypertension; however, a causal relationship has not been established. Instances of hemodynamic or idiosyncratic reactions to preparations of Technetium Tc 99m albumin aggregated have been reported. Moreover, the intravenous administration of any particulate material such as albumin aggregated imposes a temporary, small mechanical impediment to blood flow. While this effect is expected to be physiologically insignificant in most patients, administration is possibly hazardous in acute cor pulmonale and other states of severely impaired pulmonary blood flow. The use of Technetium Tc 99m albumin aggregated injection should be approached with caution in such patients.

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

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