Fabrazyme Disease Interactions
There is 1 disease interaction with Fabrazyme (agalsidase beta).
Alpha-galactosidase A proteins (applies to Fabrazyme) cardiac function
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Heart Disease
Appropriate medical support measures should be readily available when administering alpha-galactosidase A enzyme replacement therapy (ERT) due to the potential for severe infusion-associated reactions. Compromised cardiac function may predispose patients to a higher risk of severe complications from infusion-associated reactions. Closely monitor patients with compromised cardiac function during administration of ERT.
References (2)
- (2021) "Product Information. Fabrazyme (agalsidase beta)." Genzyme Corporation, SUPPL-5309
- (2023) "Product Information. Elfabrio (pegunigalsidase alfa)." Chiesi USA, Inc
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Fabrazyme drug interactions
There are 5 drug interactions with Fabrazyme (agalsidase beta).
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
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