vidarabine (Ophthalmic route)
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
Therapeutic Class: Antiviral
Pharmacologic Class: Antimetabolite
Chemical Class: Purine Nucleoside Analog
Uses For vidarabine
Vidarabine ophthalmic preparations are used to treat virus infections of the eye.
Vidarabine is available only with your doctor's prescription.
Before Using vidarabine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For vidarabine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to vidarabine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Although there is no specific information comparing use of vidarabine in children with use in other age groups, it is not expected to cause different side effects or problems in children than it does in adults.
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of vidarabine in the elderly with use in other age groups.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Proper Use of vidarabine
- First, wash your hands. Then pull the lower eyelid away from the eye to form a pouch. Squeeze a thin strip of ointment into the pouch. A 1.25-cm (approximately ½-inch) strip of ointment is usually enough unless otherwise directed by your doctor. Gently close the eyes and keep them closed for 1 or 2 minutes to allow the medicine to come into contact with the infection.
- To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). After using vidarabine eye ointment, wipe the tip of the ointment tube with a clean tissue and keep the tube tightly closed.
Do not use vidarabine more often or for a longer time than your doctor ordered. To do so may cause problems in the eyes. If you have any questions about this, check with your doctor.
To help clear up your infection completely, keep using vidarabine for the full time of treatment, even if your symptoms have disappeared. Do not miss any doses.
The dose of vidarabine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of vidarabine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For ophthalmic ointment dosage forms:
- For virus eye infection:
- Adults and children—Use in each eye every three hours (five times a day). After healing has occurred, the dose may be reduced to two times a day for seven days more.
- For virus eye infection:
If you miss a dose of vidarabine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Precautions While Using vidarabine
After application, eye ointments usually cause your vision to blur for a few minutes.
It is very important that you keep your appointments with your doctor. If your symptoms become worse, check with your doctor sooner.
vidarabine may cause your eyes to become more sensitive to light than they are normally. Wearing sunglasses and avoiding too much exposure to bright light may help lessen the discomfort.
vidarabine Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
- Increased sensitivity of eyes to light
- itching, redness, swelling, pain, burning, or other sign of irritation not present before use of vidarabine
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Excess flow of tears
- feeling of something in the eye
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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