Generic Name: oxymetazoline (ox-i-me-TAZ-oh-leen) (Ophthalmic route)
Medically reviewed by Drugs.com. Last updated on Oct 7, 2020.
Commonly used brand name(s)
In the U.S.
- Visine L.R.
- Visine Workplace
Available Dosage Forms:
Therapeutic Class: Decongestant
Chemical Class: Oxymetazoline
Uses for Upneeq
Oxymetazoline is used to treat acquired blepharoptosis, a condition wherein there is drooping or abnormal lowering of the upper eyelid.
This medicine is available without a prescription. Your doctor may have special instructions on the proper use and dose for your medical problem.
Before using Upneeq
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of oxymetazoline in children younger than 13 years of age. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of oxymetazoline in the elderly.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Methylene Blue
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Brain or heart problems (eg, insufficiency) or
- Heart or blood vessel disease, severe or unstable or
- Hypertension (high blood pressure), unstable or
- Hypotension (low blood pressure), orthostatic or unstable or
- Sjogren's syndrome—Use with caution. May make these conditions worse.
- Use of soft contact lenses—Because of the preservative in this medicine, some eye conditions may get worse if this medicine is used on top of soft contact lenses.
Proper use of Upneeq
This section provides information on the proper use of a number of products that contain oxymetazoline. It may not be specific to Upneeq. Please read with care.
Do not use oxymetazoline ophthalmic solution if it becomes cloudy or changes color.
- First, wash your hands. With the middle finger, apply pressure to the inside corner of the eye (and continue to apply pressure for 1 or 2 minutes after the medicine has been placed in the eye). Tilt the head back and with the index finger of the same hand, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close the eyes. Do not blink. Keep the eyes closed for 1 or 2 minutes to allow the medicine to be absorbed.
- To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed.
Use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for more than 72 hours, unless otherwise directed by your doctor. To do so may make your eye irritation worse and may also increase the chance of side effects.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For ophthalmic solution (eye drops) dosage form:
- For eye redness:
- Adults and children 13 years of age and older—Use 1 drop in the eye every six hours.
- Children up to 13 years of age—Use and dose must be determined by your doctor.
- For eye redness:
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Precautions while using Upneeq
If eye pain or change in vision occurs or if redness or irritation of the eye continues, gets worse, or lasts for more than 72 hours, stop using the medicine and check with your doctor.
Upneeq side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
When this medicine is used for short periods of time at low doses, side effects usually are rare.
Check with your doctor as soon as possible if any of the following side effects occur:
With overuse or long-term use
- Increase in irritation or redness of eyes
Symptoms of too much medicine being absorbed into the body
- Fast, irregular, or pounding heartbeat
- headache or lightheadedness
- trouble in sleeping
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Upneeq (oxymetazoline ophthalmic)
- Side Effects
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- 1 Review
- FDA Alerts (1)
- FDA Approval History