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bentiromide (Oral route)


Available Dosage Forms:

  • Solution

Therapeutic Class: Diagnostic Agent, Pancreatic Function

Uses For bentiromide

Bentiromide is used to help find out if the pancreas is working the way it should. The pancreas helps break down the bentiromide almost the same way it helps to break down food.

After bentiromide is broken down, a part of it appears in the urine. By measuring how much appears in the urine, your doctor can tell how well your pancreas is working.

How the test is done: Bentiromide is given by mouth as a single dose. After you take bentiromide, all of your urine is collected for the next six hours. The total amount is measured and a small sample is saved and examined. Your doctor may repeat the test after seven days.

bentiromide was withdrawn from the U.S. market in October 1996.

Before Using bentiromide

In deciding to use a diagnostic test, any risks of the test must be weighed against the good it will do. This is a decision you and your doctor will make. Also, other things may affect test results. For this test, the following should be considered:


Tell your doctor if you have ever had any unusual or allergic reaction to bentiromide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Studies on bentiromide have been done only in older children and adult patients, and there is no specific information comparing use of bentiromide in children up to 6 years of age with use in other age groups.


Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of bentiromide in the elderly with use in other age groups.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this diagnostic test, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Receiving this diagnostic test with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Methotrexate

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this diagnostic test. Make sure you tell your doctor if you have any other medical problems, especially:

  • Disease of the stomach and intestines or
  • Kidney disease or
  • Liver disease (severe)—These medical problems may cause false test results

Proper Use of bentiromide


The dose of bentiromide will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of bentiromide. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

bentiromide Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

  • Shortness of breath or troubled breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Diarrhea
  • headache
Less common or rare
  • Gas
  • nausea and vomiting
  • weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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