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Medications for Trypanosomiasis

Other names: African Trypanosomiasis; American Trypanosomiasis; Chagas disease

About Trypanosomiasis

Trypanosomiasis or Chagas disease is caused by Trypanosoma cruzi, a parasite related to the African trypanosome that causes sleeping sickness. It is spread by reduvid bugs and is one of the major health problems in South America. Due to immigration, the disease also affects people in the United States.

Drugs used to treat Trypanosomiasis

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
pentamidine Rate Add review
Rx C N

Generic name: pentamidine systemic

Brand names:  Nebupent, Pentam, Pentam 300

Drug class: miscellaneous antibiotics, inhaled anti-infectives

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Lampit Rate Add review
Rx N X

Generic name: nifurtimox systemic

Drug class: miscellaneous antibiotics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Nebupent Rate Add review
Rx C N

Generic name: pentamidine systemic

Drug class: miscellaneous antibiotics, inhaled anti-infectives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

benznidazole Rate Add review
Rx N X

Generic name: benznidazole systemic

Drug class: miscellaneous antibiotics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Pentam Rate Add review
Rx C N

Generic name: pentamidine systemic

Drug class: miscellaneous antibiotics, inhaled anti-infectives

For consumers: dosage, interactions, side effects

Pentam 300 Rate Add review
Rx C N

Generic name: pentamidine systemic

Drug class: miscellaneous antibiotics, inhaled anti-infectives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

nifurtimox Rate Add review
Rx N X

Generic name: nifurtimox systemic

Brand name:  Lampit

Drug class: miscellaneous antibiotics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Learn more about Trypanosomiasis

Mayo Clinic Reference

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.