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Medications for Post-Exposure Prophylaxis of COVID-19

Post-exposure prophylaxis for COVID-19 is when medication is taken after you have been exposed to a person with COVID-19 to help build up protection against COVID-19, and therefore reduce the chance of developing severe COVID-19 or dying.

Post-exposure prophylaxis for COVID-19 is not a substitute for vaccination against COVID-19.

Prophylaxis after exposure to COVID-19 is only used for specific patients and in specific circumstances.

Post-exposure prophylaxis is used for patients who are:

  • at high risk of progressing to be hospitalized or dying if they get COVID-19 and
  • have not been fully vaccinated or their immune system is not expected to respond to a completed course of COVID19 vaccine and
  • they have had close contact with someone who has COVID-19 or
  • they live or work in an institutional setting where someone else has COVID-19 and they are at a high risk of exposure.

Drugs used to treat Post-Exposure Prophylaxis of COVID-19

The following list of medications are in some way related to or used in the treatment of this condition.

Filter
Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
bamlanivimab / etesevimab EUA Rate Add review
Rx U

Generic name: bamlanivimab / etesevimab systemic

Brand name:  bamlanivimab and etesevimab

For consumers:

For professionals: Prescribing Information

Emergency Use Authorization: Yes

REGEN-COV EUA Rate Add review
Rx N

Generic name: casirivimab / imdevimab systemic

Drug class: antiviral combinations

For consumers: dosage, interactions,

For professionals: AHFS DI Monograph, Prescribing Information

Emergency Use Authorization: Yes

bamlanivimab and etesevimab EUA Rate Add review
Rx U

Generic name: bamlanivimab / etesevimab systemic

For consumers:

For professionals: AHFS DI Monograph

Emergency Use Authorization: Yes

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.