Skip to main content

Clozaril User Reviews & Ratings

Clozaril has an average rating of 9.0 out of 10 from a total of 13 reviews on Drugs.com. 77% of reviewers reported a positive experience, while 15% reported a negative experience.

Condition Avg. Rating Reviews Compare
Schizophrenia  
9.0
13 reviews for Schizophrenia 53 medications
Add your review

Reviews for Clozaril

  • Alexis
  • Taken for 5 to 10 years
  • June 10, 2019

For Schizophrenia "My brother was also lucky to be on Clozaril. I was watching a news report on the drug on TV one day. It stated that it brought people back who had Schizophrenia. It gave high percentages and stated that they were even able to carry a job. I spoke with my Mother and she worked to get this drug for him. He was so normal on it, like he woke up and was himself again. He was able to live in an apartment and work a 40 hour job. On his off hours, he joined a band and played trumpet on some evenings and weekends in clubs and restaurants. He was able to go out on dates. He wanted to complete his degree in music. How wonderful it was for him to have a real life to enjoy."

Was this helpful?YesNo
253 Report
  • Anonymous
  • May 6, 2009

For Schizophrenia "This medicine works. We had exhausted every other psych medicine on the market over a period of 6 years. My daughter is functioning again. The paranoid symptoms have disappeared. It is worth the monthly lab work. She's been on for 5 years, and no side effects. I don't think our daughter would be alive if not for this medicine."

10 / 10
Was this helpful?YesNo
293 Report
  • Anonymous
  • July 26, 2011

For Schizophrenia "My friend has been on Clozaril (Clozapine) for nearly 18 years. He went more than 10 years without having a single psychotic breakdown, which only occurred when he lowered the dosage himself. Even though the medicine makes him feel fatigued he has been able to hold down a 40hr/wk job. Nothing short of a God-given miracle!"

10 / 10
Was this helpful?YesNo
219 Report
  • Older...
  • January 9, 2011

For Schizophrenia "My youngest brother has suffered with Schizophrenia for around twenty years & we have also tried him on many meds - some good, some not so good. The main problem is the anguish etc. he undergoes each time he has to be "weaned" off one med & put on another. This is because after a while they all lose their effect & periodically need changing - not so with Clozaril. After being on it for five years, he is still stable, although a recent lessening of his regular dose is causing some anxiety. We hope to have the dosage resumed as previous, but see no need at this time to change him from this excellent medication."

9 / 10
Was this helpful?YesNo
184 Report
  • Centu...
  • November 6, 2011

For Schizophrenia "My brother's schizophrenia manifested itself in 1971 or 2 when he was around 17. Spent maybe 25 years in state hospital and was on everything and every combination of medicine over the years. The doctors were baffled. He was one of the first to try Clozaril when it first came out in 1980-something. Unfortunately, he was one of the few who had a severe reaction which nearly cost him his life. So sad...BUT I am very happy to read how others have found Clozaril to be such a 'miracle' for them! The trauma and grief of schizophrenia leaves years of devastation in it's wake. I am still hopeful that one day he will have his 'miracle breakthrough' just as others have!"

Was this helpful?YesNo
171 Report

Are you taking this medicine?

  • candyb
  • September 25, 2012

For Schizophrenia "My older brother has had schizoprenia since he was 14 years old in 1970's. He has been on many, many medicines with some or little success. He was then put on Clozaril in his thirty's, what a miracle Clozaril was. He was able to live a almost normal life for over 10 years and within 3 days his life went from happy to hell again, because of his blood test result, we tried to get him back on it but due to the special list with people who have reactions to it are not able to ever take it again. My brother is one of the lucky one's though he has a family that totally supports him and encourages him to live and do the best that he can. He lives in a adult facility that takes care of his needs and makes sure he gets his medicines."

9 / 10
Was this helpful?YesNo
138 Report
  • The...
  • March 16, 2014

For Schizophrenia "My sister was diagnosed with schizophrenia at about 29 after a third suicide attempt and full blown nervous breakdown. She was eventually placed in a state mental institution for ten years. She only got out due to Clozaril. They tried it on three patients through the national institute of health in Washington, DC. She was released to a halfway house within three months. Although she is still very ill, she remains on this medicine for approximately 23 or more years. "

9 / 10
Was this helpful?YesNo
121 Report
  • Mother
  • Taken for 1 to 6 months
  • March 27, 2022

For Schizophrenia "This is the only antipsychotic that worked well with few side effects. Only side effect has been Tachycardia-treated with beta blockers. Almost complete recovery after 2 months. Just needs tweaking to get a bit more improvement. Voices and hallucinations gone. Personality slowly coming back. Motivation much improved. Organisation skills greatly improved. The worry is that as a daily medication it can be forgotten and decline is quick without so needs someone to check tablets are taken. This is after 5 months use but improvement came after one and half months use. Try not to smoke."

9 / 10
Was this helpful?YesNo
32 Report
  • Elzy
  • Taken for 2 to 5 years
  • October 20, 2016

For Schizophrenia "Been on clozapine for over two years. before this I had tried many different oral and depot medications which helped then seem to had run there course with me. although it can take a while to get over the fatigue it causes it definitely helps with voices and delusions as well as just making you feel normal again."

7 / 10
Was this helpful?YesNo
82 Report
  • Flowe...
  • Taken for 6 months to 1 year
  • September 3, 2021

For Schizophrenia "Clozaril (Clozapine) is the best antipsychotic I’ve ever tried (and I’ve tried many other medications). It lessened my symptoms and now I’m functioning better. I had drooling at night, constipation, sedation. I take Senokot for the constipation, a medication to lessen the drooling (though I don’t use it), and I take the majority of my Clozapine at night to deal with the sedation."

8 / 10
Was this helpful?YesNo
26 Report
  • Jerio
  • Taken for 1 to 2 years
  • March 18, 2018

"This drug is too dangerous It is too difficult to titrate off and it causes rebound psychosis with a vengeance, along with vomiting and excruciating headaches While on this drug it shuts down the brain and body causing obesity and constipation It is sad to know this drug can be forced onto humans with "no consent" as it really will ruin you life unless you prefer a chemical restraint The blood draws are nearly impossible for people who are not wanting to take this but if you abruptly stop this drug you will feel like you are dying 350 mg was a chemical restraint and our family member lost his whole personality and ability to function at all on this mind alternating drug with 5 black box warning Do not start this drug unless you like mind torture"

1 / 10
Was this helpful?YesNo
35 Report
  • ceeec...
  • Taken for 10 years or more
  • March 15, 2023

"My former doctor put me on this and I have been on this for 10-plus years. It hid all my emotions. I could not feel anything, but she insisted it was the only thing I could be on. Since this drug is used primarily for schizophrenia, I was reluctant to take it in the first place. But, I trusted the doctor. I gained over 60 pounds in the first 6 weeks. You have to get monthly bloodwork for the whole duration you are on the drug. It is illegal in some countries. The risks, in my opinion, outway the benefits."

1 / 10
Was this helpful?YesNo
9 Report
  • Sabrina
  • Taken for 10 years or more
  • March 22, 2019

For Schizophrenia "I had Major Depression with psychotic features and have been on clozaril for 11 blessed years, it works so well. I have long ago lost track of all the antipsychotics and antidepressants I have tried."

10 / 10
Was this helpful?YesNo
63 Report
  • MATT
  • April 29, 2013

For Schizophrenia "I have been taking a small dose 100mg to treat my schizoaffective disorder. I think it helps lower my agitation and helps me to think more clearly. I don't think it helps with my paranoia."

8 / 10
Was this helpful?YesNo
95 Report
  • Anonymous
  • September 14, 2009

For Schizophrenia "Fabulous medicine for schizophrenia"

10 / 10
Was this helpful?YesNo
101 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.