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Lithium Toxicity

Medically reviewed by Last updated on Mar 3, 2024.

What is lithium toxicity?

Lithium toxicity happens when the amount of lithium in your blood is too high. Lithium is a medicine that is used to treat depression and bipolar disorder.

What causes lithium toxicity?

Toxicity can occur if you take a large dose of lithium at one time. Toxicity can also be caused by taking a slightly higher dose of lithium over time. It can also occur if you are dehydrated, or you take medicines that cause lithium to build up in your blood. These medicines may include NSAIDs, certain blood pressure medicines, and medicines used to treat epilepsy. A decreased intake of sodium (salt) can also lead to lithium toxicity.

What are the signs and symptoms of mild to moderate lithium toxicity?

What are the signs and symptoms of severe lithium toxicity?

How do I safely take lithium?

What should I do if I think I or someone I know took too much lithium?

Call the Poison Control Center at 1-800-222-1222 immediately.

Call 911 or have someone else call for any of the following:

When should I seek immediate care?

When should I contact my healthcare provider?

Care Agreement

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.