Skip to Content



Epididymitis is inflammation of your epididymis. The epididymis is a long curled tube inside your scrotum. It stores and carries sperm from your testicles to your penis. Acute epididymitis lasts for 6 weeks or less and becomes chronic if it lasts longer than 3 months.

Subsequent Epididymitis



  • Antibiotics: This medicine is given if epididymitis is caused by a bacterial infection. Take them as directed.
  • NSAIDs: These medicines decrease swelling, pain, and fever. NSAIDs are available without a doctor's order. Ask which medicine is right for you and how much to take. Take as directed. NSAIDs can cause stomach bleeding or kidney problems if not taken correctly.
  • Pain medicine: You may be given a prescription medicine to decrease pain. Do not wait until the pain is severe before you take this medicine.
  • Take your medicine as directed. Call your healthcare provider if you think your medicine is not helping or if you have side effects. Tell him if you are allergic to any medicine. Keep a list of the medicines, vitamins, and herbs you take. Include the amounts, and when and why you take them. Bring the list or the pill bottles to follow-up visits. Carry your medicine list with you in case of an emergency.

Follow up with your healthcare provider as directed:

You may need to return for blood tests or other testing after you are done with treatment. Write down your questions so you remember to ask them during your visits.


  • Ice: Ice helps decrease swelling and pain. Ice may also help prevent tissue damage. Use an ice pack or put crushed ice in a plastic bag. Cover it with a towel and place it on your swollen testicle or scrotum for 15 to 20 minutes every hour as directed.
  • Rest: Rest or decreased activity may help decrease your pain. It may also help you heal faster. Return to normal activities as directed.
  • Safe sex: Use a latex condom during oral, vaginal, or anal sex. Do not have sex with someone who has an STI. If you have an infection, let your sexual partner know so they can be checked for an STI and treated if needed. Do not have sex while you or your partner is being treated for an STI, or until your healthcare provider says that it is okay.
  • Scrotal support: You may be told to put a pillow or rolled up towel under your scrotum to elevate your scrotum when you sit or lie down. This may help reduce your pain. An athletic supporter may make you more comfortable when you stand.

Contact your healthcare providerif:

  • You have a fever.
  • Your signs and symptoms do not improve within 3 days of treatment or come back after treatment.
  • You have questions or concerns about your condition or care.

Seek care immediately or call 911 if:

  • You feel lightheaded or faint.
  • You have severe pain in your testicles that starts suddenly or follows an injury.
  • Your symptoms become worse, even after you start treatment with medicine.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Learn more about Epididymitis (Discharge Care)

Associated drugs

IBM Watson Micromedex

Mayo Clinic Reference