Carboplatin Plus Etoposide Plus Atezolizumab Chemo Regimen
Medically reviewed by Drugs.com. Last updated on Feb 9, 2025.
Carboplatin plus etoposide plus atezolizumab chemo regimen:
Your doctor will prescribe the dose of each medicine and the infusion schedule. Infusions will happen in a hospital or cancer treatment center. The medicines need to be given on a fixed schedule. If you need to miss a dose, call your doctor or treatment clinic immediately.
- The following infusion cycle may repeat every 21 days for 4 cycles:
- Atezolizumab and carboplatin IV over 30 to 60 minutes on Day 1
- Etoposide IV over 60 minutes on Days 1, 2, and 3
- Maintenance cycle: atezolizumab IV over 60 minutes once every 3 weeks
Before you receive these medicines:
- Ask questions if you do not understand what your doctor or nurse is telling you about the medicines. Make sure you understand all the risks and benefits of this treatment.
- Talk to your doctor about all your current medicines and supplements. Do not take any medicines or supplements unless they have been discussed with your doctor.
- Talk to your doctor about pregnancy and breastfeeding. Medicines in this regimen may harm an unborn baby. You may need to avoid getting pregnant or breastfeeding during treatment or as directed.
- Tell your doctor if you have kidney disease, liver disease, breathing or lung problems, diabetes, immune system problems (including Crohn disease, ulcerative colitis, lupus), nervous system problems (including Guillain-Barré syndrome, myasthenia gravis), or any type of infection. Tell your doctor if you have had an organ transplant.
On each infusion day:
- Blood may be drawn to make sure the doses you are being given are right for you.
- Medicines may be given to help with nausea and vomiting and to decrease your risk for reactions.
- Talk to your doctor before you get a flu shot or other vaccine. Tell your doctor if you have been around anyone who has chickenpox or any other infections. Do not have close personal contact with anyone who has recently received an oral polio vaccine.
Infusion precautions:
- Contact your doctor or nurse immediately if you feel short of breath or have trouble breathing during or after your infusion.
- Tell the doctor or nurse right away if you notice redness, pain, or swelling at the infusion site.
After each infusion:
- If possible, have someone stay with you to call for help if you have serious side effects.
- Drink extra liquids to help prevent nausea and to keep your kidneys and liver working well.
- You may be at risk for infections. Wash your hands often with soap and water. Do not have close contact with anyone who is sick. Ask your doctor about vaccines you may need to prevent infections.
Call your local emergency number (911 in the US) if you have any of the following:
- Chest pain
- Trouble breathing
- Lightheadedness, dizziness, fainting
Call your nurse or doctor immediately if you have any of the following:
- Worsening cough
- Bloody or black, tarry bowel movements, diarrhea, severe stomach pain
- Unusual bleeding, bruising, or weakness
- Blistering, peeling, red skin rash
- Pelvic pain, urinating often
- Ringing in the ears, hearing loss
- Numbness, tingling, or burning pain in your hands, arms, legs, or feet
- Dark urine or pale bowel movements, nausea, vomiting, loss of appetite, yellow skin or eyes
- Fever, chills, cough, sore throat, or body aches
Talk to your nurse or doctor if you have any of the following:
- Pain, redness, or swelling at the infusion site
- Nausea and vomiting
- Abdominal pain
- Constipation, decreased appetite, hair loss
Follow up with your oncologist as directed:
Your oncologist will need to check your progress at regular visits. Blood tests may be needed to check for side effects.
Care Agreement
You have the right to help plan your care. Learn about your health condition and how it may be treated. Discuss treatment options with your healthcare providers to decide what care you want to receive. You always have the right to refuse treatment. The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.© Copyright Merative 2025 Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.
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