Generic Name: Miltefosine (mil TEF oh seen)
Brand Name: Impavido
Medically reviewed by Drugs.com. Last updated on Aug 7, 2020.
- Do not take if you are pregnant.
- Use of Impavido (miltefosine) during pregnancy may cause birth defects or death of the unborn baby. You will need to have a pregnancy test to show that you are NOT pregnant before starting Impavido (miltefosine). Talk with the doctor.
- Use birth control you can trust to prevent pregnancy while you are taking Impavido (miltefosine) and for 5 months after you stop taking it.
- If you get pregnant while taking Impavido (miltefosine) or within 5 months after your last dose, call your doctor right away.
Uses of Impavido:
- It is used to treat a certain type of infection (leishmaniasis).
What do I need to tell my doctor BEFORE I take Impavido?
- If you have an allergy to miltefosine or any other part of Impavido (miltefosine).
- If you are allergic to Impavido (miltefosine); any part of Impavido (miltefosine); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you are breast-feeding. Do not breast-feed while you take Impavido (miltefosine) and for 5 months after you stop taking it.
- If you have a health problem called Sjogren-Larsson-Syndrome.
This is not a list of all drugs or health problems that interact with Impavido (miltefosine).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Impavido (miltefosine) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Impavido?
- Tell all of your health care providers that you take Impavido (miltefosine). This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This medicine caused fertility problems in animals. It is not known if it will cause fertility problems in humans. Talk with the doctor.
- If diarrhea happens or you are throwing up, call your doctor. You will need to drink more fluids to keep from losing too much fluid.
- If you throw up or have diarrhea, birth control pills may not work as well. If you take birth control and this happens, use an extra form of birth control like condoms.
How is this medicine (Impavido) best taken?
Use Impavido (miltefosine) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take with food.
- Swallow whole. Do not chew, break, open, or dissolve.
- Keep taking Impavido (miltefosine) as you have been told by your doctor or other health care provider, even if you feel well.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
- Any unexplained bruising or bleeding.
- For males, testicle pain.
- Orgasm with less or no semen.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
What are some other side effects of Impavido?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Upset stomach or throwing up.
- Stomach pain or diarrhea.
- Not hungry.
- Feeling dizzy, sleepy, tired, or weak.
- Motion sickness.
If OVERDOSE is suspected:
How do I store and/or throw out Impavido?
- Store in the original container at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Impavido (miltefosine) is refilled. If you have any questions about Impavido (miltefosine), please talk with the doctor, pharmacist, or other health care provider.
More about Impavido (miltefosine)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: anthelmintics
- FDA Approval History