Generic Name: Asfotase Alfa (AZ fo tase AL fa)
Brand Name: Strensiq
Medically reviewed by Drugs.com. Last updated on Aug 31, 2020.
Uses of Asfotase Alfa:
- It is used to treat a health problem that leads to bone and teeth growth that is not normal called hypophosphatasia.
What do I need to tell my doctor BEFORE I take Asfotase Alfa?
- If you are allergic to asfotase alfa; any part of asfotase alfa; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take asfotase alfa with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Asfotase Alfa?
- Tell all of your health care providers that you take asfotase alfa. This includes your doctors, nurses, pharmacists, and dentists.
- Have an eye exam as you have been told by your doctor.
- Follow up with the doctor as you have been told.
- This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take asfotase alfa.
- If your weight changes, talk with your doctor. The dose of asfotase alfa may need to be changed.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using asfotase alfa while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Asfotase Alfa) best taken?
Use asfotase alfa as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into the fatty part of the skin on the top of the thigh, belly area, or upper arm.
- If you will be giving yourself the shot, your doctor or nurse will teach you how to give the shot.
- Use within 1 hour of taking out of the refrigerator.
- Do not shake.
- This product is clear but may contain a few particles. Do not use if the solution is cloudy, leaking, or has more than a few particles.
- This medicine is colorless to a faint yellow. Do not use if the solution changes color.
- Do not give into red or irritated skin.
- Move the site where you give the shot with each shot.
- Throw away any part of the opened vial not used after the shot is given.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Upset stomach or throwing up.
- Eye or eyelid swelling.
- Dizziness or passing out.
- Fever or chills.
- Feeling irritable.
- Numbness or tingling in the mouth.
- Thick skin, pits, or lumps where the injection was given.
What are some other side effects of Asfotase Alfa?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Irritation where the shot is given.
- Change in skin color where the shot was given.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Asfotase Alfa?
- Store in a refrigerator. Do not freeze.
- Do not use if it has been frozen.
- Store in original container.
- Protect from light.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about asfotase alfa, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.