Vestronidase Alfa Levels and Effects while Breastfeeding
Summary of Use during Lactation
No information is available on the clinical use of vestronidase alfa during breastfeeding. Because vestronidase alfa is a large protein molecule with a molecular weight of about 290,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. If vestronidase alfa is required by the mother, it is not a reason to discontinue breastfeeding. Until more data are available, vestronidase alfa should be used with careful infant monitoring during breastfeeding.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Substance Identification
Substance Name
Vestronidase Alfa
CAS Registry Number
1638194-78-1
Drug Class
Breast Feeding
Lactation
Milk, Human
Enzymes
Glucuronidase
Chondroitinsulfatases
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