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Gadobutrol use while Breastfeeding

Drugs containing Gadobutrol: Gadavist

Gadobutrol Levels and Effects while Breastfeeding

Summary of Use during Lactation

There is no published experience with gadobutrol during breastfeeding. Guidelines developed by several professional organizations state that breastfeeding need not be disrupted after a nursing mother receives a gadolinium-containing contrast medium.[1][2][3] Gadobutrol is one of the most stable gadolinium agents, theoretically making it one of the safer drugs to use during breastfeeding. However, because there is no published experience with gadobutrol during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Gadopentetate, Gadoteridol, Gadoterate

References

1. American College of Radiology Committee on Drugs and Contrast Media. Administration of contrast media to breast-feeding mothers. In, ACR manual on contrast media. 2015;Version 10.1:99-100. http://www.acr.org/~/media/ACR/Documents/PDF/QualitySafety/Resources/Contrast%20Manual/2015_Contrast_Media.pdf

2. Patenaude Y, Pugash D, Lim K et al. The use of magnetic resonance imaging in the obstetric patient. J Obstet Gynaecol Can. 2014;36:349-55. PMID: 24798674

3. Committee Opinion No. 656: Guidelines for Diagnostic Imaging During Pregnancy and Lactation. Obstet Gynecol. 2016;127:e75-80. PMID: 26942391

Gadobutrol Identification

Substance Name

Gadobutrol

CAS Registry Number

770691-21-9

Drug Class

Contrast Media

Diagnostic Agents

Administrative Information

LactMed Record Number

991

Last Revision Date

20160819

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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