Skip to main content

Dyphylline use while Breastfeeding

Medically reviewed by Last updated on Dec 4, 2021.

Drugs containing Dyphylline: Dilor-400, Dyphylline GG ES, Dyfilin GG, Dylix, Dilor, Lufyllin, Neothylline, Lufyllin-400, Lufyllin-EPG, Lufyllin-GG, Show all 26 »Dilex-G, Dyphylline GG, Dyphyl GG, Difil G, Difil-G Forte, Dyline GG, Panfil G, Dy-G, Dilor-G, Dyflex-G, LGG, D-G, Dyphyllin-GG, Dilex-G 400, Dilex-G 200, Jay-Phyl

Dyphylline Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because of the relatively high levels in milk and a previous report with theophylline, occasional stimulant effects in infants should be anticipated in breastfed infants. No severe adverse reactions are expected. Amounts in milk can be minimized by avoiding breastfeeding for 3 to 4 hours after a dose.

Drug Levels

Maternal Levels. After intramuscular administration of a single 5 mg/kg dose of dyphylline, peak milk levels usually occurred between 2 and 4 hours after the dose in 20 subjects. Peak milk levels averaged 24.3 mg/L.[1]

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Albuterol, Aminophylline, Theophylline


Jarboe CH, Cook LN, Malesic I, Fleischaker J. Dyphylline elimination kinetics in lactating women: blood to milk transfer. J Clin Pharmacol. 1981;21:405-10. [PubMed: 7309903]

Substance Identification

Substance Name


CAS Registry Number


Drug Class

  • Breast Feeding
  • Lactation
  • Anti-Asthmatic Agents
  • Bronchodilator Agents

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

More about dyphylline

Patient resources

Other brands
Dilor-400, Dylix, Dilor, Lufyllin, Lufyllin-400

Related treatment guides

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.