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Topamax News

Specific Antiseizure Medications Associated With Major Malformations in Infants

FRIDAY, July 18, 2025 – Maternal use of valproate, phenobarbital, and topiramate early in pregnancy is associated with an increased risk for major malformations in infants compared with lamotrigine,...

Many Women With Epilepsy Unaware of Seizure Meds' Risks to Pregnancy

FRIDAY, Dec. 6, 2024 – Many women with epilepsy who are of childbearing age might not realize their anti-seizure drugs can raise the risk of birth defects or dampen the effectiveness of their birth...

FDA Approves Topamax for Migraine Prevention in Adolescents

March 28, 2014 – Today, the U.S. Food and Drug Administration approved Topamax (topiramate) for prevention (prophylaxis) of migraine headaches in adolescents ages 12 to 17. This is the first FDA...

FDA Medwatch Alert: Topamax (topiramate)

[UPDATE November 10, 2005] Letters from Novartis Pharmaceuticals Corporation added below [UPDATE September 30, 2005] Letters from Ortho-McNeil Neurologics, Inc. added below [Posted 09/26/2005]...

FDA Medwatch Alert: Topamax (topiramate) Tablets/Sprinkle Capsules - Jul 10, 2003

Ortho-McNeil and FDA revised the WARNINGS and PRECAUTIONS sections of the prescribing information to provide updated information about oligohidrosis (decreased sweating) and hyperthermia, which have...

FDA Medwatch Alert: Topamax (topiramate) Tablets/Sprinkle Capsules - Dec 30, 2003

Ortho-McNeil and FDA revised the WARNINGS and PRECAUTIONS sections of the prescribing information, notifying healthcare professionals that Topamax causes hyperchloremic, non-anion gap metabolic...

FDA Medwatch Alert: Antiepileptic Drugs

[UPDATE 05/05/2009] FDA notified healthcare professionals that it approved updated labeling for antiepileptic drugs used to treat epilepsy, psychiatric disorders, and other conditions (e.g., migraine...

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Migraine Prevention, Migraine Prophylaxis, Lennox-Gastaut Syndrome, Epilepsy, Seizure Prevention, Seizure Prophylaxis, Seizures

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