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Organ Transplant - Rejection Prophylaxis News

One Reason Why Kidney Transplants Fail

Posted 15 Aug 2018 by Drugs.com

WEDNESDAY, Aug. 15, 2018 – Scottish scientists say they've found new clues to why some kidney transplants fail. It has to do with the amount of "wear and tear" a transplanted kidney has and how that affects its work in the recipient, the new study says. It was known that the age of the donor could affect how well a transplanted kidney worked, but this is the first time that the "burden of ...

How Transplanted Livers Guard Against Organ Rejection

Posted 27 Apr 2018 by Drugs.com

FRIDAY, April 27, 2018 – People who get a liver transplant often require less anti-rejection medication, and new research helps explain why. "This study shows that the liver transplant itself regulates the host's immune responses. Compared to the other organs, the liver is immunologically a very active organ, so it is capable of regulating the immune responses against itself," explained study ...

Surgeons Safely Transplant Kidneys From Donors With Hep C

Posted 6 Mar 2018 by Drugs.com

TUESDAY, March 6, 2018 – In what could be a breakthrough in the world of organ transplants, Johns Hopkins researchers have taken kidneys from people infected with hepatitis C and safely transplanted them without transmitting the disease. The surgeries gave new kidneys to 10 donor recipients – just a handful of the more than 420,000 Americans who currently struggle with potentially fatal ...

'Old' Lungs May Be Good Transplant Options

Posted 9 Nov 2017 by Drugs.com

THURSDAY, Nov. 9, 2017 – Lungs from older donors are a viable option for lung transplants and should be considered more often, a new study suggests. Survival rates for younger recipients of lung transplants from donors older than 60 are similar to those who receive lungs from younger donors, researchers found. The University of Louisville team analyzed more than 14,000 lung transplants received ...

Limiting 'Cold Time' Could Make More Organs Available for Transplant

Posted 6 Oct 2017 by Drugs.com

THURSDAY, Oct. 5, 2017 – By improving the way certain donated organs are handled before a transplant, more organs could end up being used, new research suggests. The concern centers on organs donated following "circulatory death" (DCD). That means a patient's heart, breathing and circulation stop functioning. Most donated organs come from people who are brain dead, but their circulation is ...

Novel Procedure Improves Kidney Transplant Success

Posted 3 Aug 2017 by Drugs.com

WEDNESDAY, Aug. 2, 2017 – A new treatment might open the door for more patients with advanced kidney disease to get a transplant, a preliminary study suggests. Of the 100,000-plus Americans waiting for a donor kidney, about one-third are "sensitized," said Dr. Robert Montgomery, director of the Transplant Institute at NYU Langone in New York City. Those patients face a tough situation: They ...

Donor Kidneys Rejected by Centers 7 Times on Average

Posted 27 Jul 2017 by Drugs.com

THURSDAY, July 27, 2017 – A donated kidney is turned away for transplant an average of seven times before reaching the patient who finally receives it, a new study shows. Transplant centers regularly reject kidneys based on a donor's age or perceived quality of the organ, even though these kidneys are eventually accepted and work well for people farther down the waiting list, explained lead ...

Researchers Grow Functioning Liver Tissue in Mice

Posted 19 Jul 2017 by Drugs.com

WEDNESDAY, July 19, 2017 – Researchers say they were able to coax tiny "seeds" of liver tissue into fully functioning livers in mice. If this approach works in people, it could help reduce long wait lists for liver transplants. It might also benefit people with failing livers who don't quality for liver transplants, according to the researchers. The scientists placed three types of liver cells ...

Kidneys From Deceased Diabetics Might Ease Organ Shortage: Study

Posted 25 May 2017 by Drugs.com

THURSDAY, May 25, 2017 – Kidneys from deceased diabetic donors can save the lives of patients on the transplant wait-list, researchers say. For the study, investigators compared U.S. data from more than 8,100 recipients of kidneys from deceased diabetic donors with data from people on the kidney transplant wait-list. The patients were followed for an average of nearly nine years. People who ...

Cancer Risk Rises After Childhood Organ Transplant: Study

Posted 26 Apr 2017 by Drugs.com

WEDNESDAY, April 26, 2017 – Children given an organ transplant have a substantially higher risk of developing cancer – in some cases up to 200 times higher – than the general population, a new study finds. But the individual risk of any one child getting cancer still remains very small, the study authors stressed. Overall, the U.S. National Cancer Institute (NCI) study found that the risk for ...

Baseball Great Rod Carew Owes His Life to NFL Player's Transplanted Organs

Posted 17 Apr 2017 by Drugs.com

MONDAY, April 17, 2017 – When Baseball Hall of Famer Rod Carew received a new heart and kidney last December, he and his family had no idea who they had to thank for the lifesaving organs. But some good sleuthing by Carew's wife and the mother of the anonymous donor unearthed a startling discovery: The organs had come from former National Football League tight end Konrad Reuland, who was only 29 ...

Cystic Fibrosis Survival Better in Canada Than in U.S.

Posted 14 Mar 2017 by Drugs.com

MONDAY, March 13, 2017 – People with cystic fibrosis are living longer than ever, but those in Canada live nearly 10 years longer than those in the United States, a new study finds. Cystic fibrosis is a genetic disease that affects the lungs and digestive tract. It causes the production of a thick, sticky mucus that clogs the lungs. This may cause life-threatening lung infections. People with ...

Kidney Transplant Survival Up Among Babies, Kids

Posted 7 Mar 2017 by Drugs.com

MONDAY, March 6, 2017 – Survival rates for children who get kidney transplants have improved significantly over the last half-century, a new study finds. "The outlook for infants and children with end-stage kidney disease was once dismal, with poor survival rates after transplant. There has been great progress in pediatric kidney transplantation, and now the patient survival rate is almost 100 ...

Non-English Speakers Less Likely to Be on Kidney Transplant List

Posted 9 Feb 2017 by Drugs.com

THURSDAY, Feb. 9, 2017 – Language barriers may prevent some eligible U.S. patients from receiving a kidney transplant, a new study suggests. Specifically, those who don't speak English may be less likely to complete the kidney transplant evaluation necessary for them to be placed on a waiting list for a kidney from a deceased donor. For the study, researchers analyzed data from kidney failure ...

Depression Often Untreated in Dialysis Patients

Posted 27 Jan 2017 by Drugs.com

THURSDAY, Jan. 26, 2017 – Depression is common among kidney failure patients undergoing dialysis. But efforts to get them on antidepressants often fail, a new study finds. Many patients refuse to start or modify depression treatment. And in some cases kidney specialists don't want their patients taking antidepressant medication, researchers reported. "Our study demonstrated that many patients on ...

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