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Organ Transplant - Rejection Prophylaxis News

Non-English Speakers Less Likely to Be on Kidney Transplant List

Posted 11 days ago by Drugs.com

THURSDAY, Feb. 9, 2017 – Language barriers may prevent some eligible U.S. patients from receiving a kidney transplant, a new study suggests. Specifically, those who don't speak English may be less likely to complete the kidney transplant evaluation necessary for them to be placed on a waiting list for a kidney from a deceased donor. For the study, researchers analyzed data from kidney failure patients across the United States. The investigators found that patients who lived in neighborhoods where more than 20 percent of households didn't speak English were 29 percent less likely to be on a kidney transplant waiting list than those in neighborhoods where less than 1 percent of households didn't speak English. Although the study can't prove a cause-and-effect relationship, the researchers found the link between not speaking English and not being on a kidney transplant waiting list was ... Read more

Related support groups: Renal Failure, Renal Transplant, Chronic Kidney Disease, Organ Transplant - Rejection Prophylaxis, Organ Transplant, Organ Transplant - Rejection Reversal, Hyperphosphatemia of Renal Failure

Depression Often Untreated in Dialysis Patients

Posted 27 Jan 2017 by Drugs.com

THURSDAY, Jan. 26, 2017 – Depression is common among kidney failure patients undergoing dialysis. But efforts to get them on antidepressants often fail, a new study finds. Many patients refuse to start or modify depression treatment. And in some cases kidney specialists don't want their patients taking antidepressant medication, researchers reported. "Our study demonstrated that many patients on chronic hemodialysis have depressive symptoms but do not wish to receive aggressive treatment to alleviate these symptoms," said study co-leader Dr. Steven Weisbord. "We also noted that when patients are willing to accept treatment, renal [kidney care] providers commonly do not prescribe treatment," said Weisbord, who's with the VA Pittsburgh Healthcare System. When kidneys fail, dialysis treatment is needed to remove wastes and salt from the blood. It's often done at a hospital, dialysis ... Read more

Related support groups: Depression, Lexapro, Zoloft, Cymbalta, Effexor, Prozac, Celexa, Major Depressive Disorder, Citalopram, Paxil, Sertraline, Pristiq, Amitriptyline, Venlafaxine, Fluoxetine, Effexor XR, Mirtazapine, Savella, Escitalopram, Remeron

Should a Mental Disability Keep Patients Off Organ Transplant Lists?

Posted 25 Jan 2017 by Drugs.com

WEDNESDAY, Jan. 25, 2017 – Pressure is mounting for the U.S. organ donation network to tackle one of the thorniest ethical questions it's ever faced – whether a person with intellectual disabilities should be denied access to a transplant. A bipartisan group of 30 legislators from the U.S. Congress petitioned the Department of Health and Human Services in October to "issue guidance on organ transplant discrimination with regards to persons with disabilities," according to a new opinion piece in the Jan. 26 New England Journal of Medicine. The legislators' request follows several highly publicized cases in which people with intellectual disabilities have either fought to receive a transplant or have been outright denied a place on a waiting list, said co-author Dr. Scott Halpern. He's an associate professor of medical ethics and health policy at the University of Pennsylvania's ... Read more

Related support groups: Depression, Bipolar Disorder, Obsessive Compulsive Disorder, Major Depressive Disorder, Schizophrenia, Mania, Paranoid Disorder, Borderline Personality Disorder, Schizoaffective Disorder, Autism, Psychosis, Renal Transplant, Psychiatric Disorders, Organ Transplant - Rejection Prophylaxis, Body Dysmorphic Disorder, Neurosis, Severe Mood Dysregulation, Organ Transplant, Organ Transplant - Rejection Reversal, Rejection Prophylaxis

Don't Rule Out Kidneys From Elderly Donors

Posted 16 Dec 2016 by Drugs.com

THURSDAY, Dec. 15, 2016 – Healthy kidneys from elderly donors are often rejected, but even kidneys from donors 80 and older can function for years after transplantation, Italian researchers report. The results were published online Dec. 15 in the Clinical Journal of the American Society of Nephrology. "The results of this study support the use of extended criteria donors, even donors older than 80 years, but they have to be accurately selected and managed with dedicated protocols," Dr. Luigi Biancone, of the University of Turin, said in a journal news release. Researchers analyzed results of deceased donor kidney transplants performed at the Turin University Renal Transplant Center between 2003 and 2013. They focused on almost 650 transplants from so-called "extended criteria" donors – donors older than 60 and those aged 50 to 59 with certain risk factors. After a follow-up of nearly ... Read more

Related support groups: Renal Failure, Renal Transplant, Chronic Kidney Disease, Organ Transplant - Rejection Prophylaxis, Peritoneal dialysis, Organ Transplant, Kidney Transplant, Graft-versus-host disease, Rejection Prophylaxis, Hyperphosphatemia of Renal Failure

New Technique Keeps Donor Lungs Viable Longer: Study

Posted 18 Nov 2016 by Drugs.com

FRIDAY, Nov. 18, 2016 – A technique that allows lungs destined for transplants to be preserved longer works well, a new Canadian study finds. The strategy, called ex-vivo lung perfusion (EVLP), allows preservation of lungs for up to 12 hours, instead of the standard six to eight hours. "We have been using EVLP ... to assess high-risk donor lungs [less healthy] for the last decade, and almost 300 patients have benefited from this technology at our centre to date," said study author Dr. Marcelo Cypel, a thoracic surgeon at Toronto General Hospital. With standard lung transplants, "donor lungs are transported cold to the hospital where they are warmed, evaluated and then cooled again until they are transplanted into the recipient," Cypel explained. The EVLP technique, which has now become more common, allows doctors to preserve lungs for longer periods by pumping them with a solution of ... Read more

Related support groups: Organ Transplant - Rejection Prophylaxis, Organ Transplant, Organ Transplant - Rejection Reversal, Respiratory Failure, Graft-versus-host disease

Doctors Perform 1st U.S. Living-Donor Uterine Transplant

Posted 5 Oct 2016 by Drugs.com

WEDNESDAY, Oct. 5, 2016 – A team of doctors in Dallas is "cautiously optimistic" of success in what would be the first living-donor uterine transplant in the United States. Doctors at Baylor University Medical Center said Wednesday that they performed four of the transplants in September, but only one has proven successful. "During the past three weeks since the first surgery, we performed routine follow-up testing as part of the trial protocol on all four patients," Baylor said in a statement. "In three patients, we determined after several tests the transplanted organs were not receiving viable blood flow and the uteri were removed. Those patients are now doing well and will soon be back to normal activity." However, "The fourth patient's follow-up tests currently indicate a much different result," Baylor said. "Her tests are showing good blood flow to the uterus. There are also no ... Read more

Related support groups: Birth Control, Contraception, Female Infertility, Organ Transplant - Rejection Prophylaxis, Organ Transplant, Diagnosis and Investigation, Rejection Prophylaxis

Organ Transplants Linked to Higher Skin Cancer Risk

Posted 21 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 21, 2016 – People who have an organ transplant may be more likely to develop skin cancer, new research suggests. The finding applies to all transplant patients, even those who are nonwhite and dark-skinned, according to Dr. Christina Lee Chung, an associate professor of dermatology at Drexel University in Philadelphia, and colleagues. The researchers said the risk increases over time with ongoing exposure to medications that suppress the immune system to prevent organ rejection. Total-body skin exams should be a routine part of care after transplant surgery, the study authors advised. For the study, the researchers analyzed medical records of 413 organ transplant recipients, 63 percent of whom were not white. The investigators found 19 new skin cancers in 15 of the nonwhite patients. That group included six black patients, five Asians and four Hispanics. Among the ... Read more

Related support groups: Basal Cell Carcinoma, Renal Transplant, Melanoma, Skin Cancer, Melanoma - Metastatic, Organ Transplant - Rejection Prophylaxis, Squamous Cell Carcinoma, Organ Transplant, Kidney Transplant, Graft-versus-host disease, History - Skin Cancer, Rejection Prophylaxis

Blood Test May Rule Out Too Many Donor Hearts

Posted 21 Jun 2016 by Drugs.com

TUESDAY, June 21, 2016 – A blood test that's used to check the health of a donor heart may not accurately predict if a heart transplant will be successful, a new study finds. Placing less emphasis on this blood test could increase the number of hearts available for end-stage heart failure, the researchers said. "Heart transplantation is an incredible therapy for patients with end-stage heart failure, but there are only 2,000 to 2,400 transplants each year," said senior study author Dr. Snehal Patel. "A lot of focus has been on finding ways to sign up more people as organ donors, but there is also a problem in that only an average of one in three donor hearts are placed," explained Patel. He is an assistant professor of medicine at Montefiore Medical Center and Albert Einstein College of Medicine in New York City. The blood test in question checks levels of a protein called troponin I. ... Read more

Related support groups: Heart Attack, Myocardial Infarction, Prevention of Cardiovascular Disease, Organ Transplant - Rejection Prophylaxis, Cardiovascular Risk Reduction, Organ Transplant, Diagnosis and Investigation, Myocardial Infarction - Prophylaxis

Obama's 3-Pronged Effort to Speed Organ Transplants

Posted 13 Jun 2016 by Drugs.com

MONDAY, June 13, 2016 – The Obama administration on Monday announced wide-ranging public and private measures to speed the wait for lifesaving organ transplants in the United States. The goals include making it easier for Americans to become organ donors and increasing the number of organ transplants. Also, almost $200 million in new investments will "facilitate breakthrough research and development," the White House said in a media release. "New breakthroughs in bioengineering, transplantation, and organ preservation can further increase the number of organ transplants and improve outcomes," the President's office said. The administration has enlisted the cooperation of dozens of corporations, universities, hospitals, foundations and patient advocacy organizations in this ongoing project. Last year, more than 30,000 transplants took place in the United States, a record number. Yet ... Read more

Related support groups: Renal Transplant, Organ Transplant - Rejection Prophylaxis, Organ Transplant, Kidney Transplant, Organ Transplant - Rejection Reversal, Graft-versus-host disease, Rejection Prophylaxis, Rejection Reversal

Cancer History May Affect Survival After Organ Transplant

Posted 22 Apr 2016 by Drugs.com

FRIDAY, April 22, 2016 – Organ transplant patients who previously had cancer may be at increased risk for new cancer and early death compared to organ recipients with no cancer history, new research suggests. The findings indicate that transplant patients with a history of cancer may need closer monitoring to detect recurrent and new cancers early, the study's senior author, Dr. Nancy Baxter, said in a news release from St. Michael's Hospital in Toronto. Baxter is chief of the hospital's General Surgery Department. She and her colleagues reviewed 33 studies that included a total of nearly 400,000 patients in 12 countries. They found that organ recipients with previous cancer were 1.5 times more likely to die prematurely from any cause than those with no previous cancer. Moreover, those with previous cancer were nearly twice as likely to develop a new cancer and had three times higher ... Read more

Related support groups: Surgery, Cancer, Renal Transplant, Organ Transplant - Rejection Prophylaxis, Kidney Transplant, Graft-versus-host disease, Rejection Reversal

Doctors Report Groundbreaking HIV-to-HIV Organ Transplants

Posted 31 Mar 2016 by Drugs.com

WEDNESDAY, March 30, 2016 – Trailblazing liver and kidney transplants from an HIV-positive donor to HIV-positive recipients were announced Wednesday by surgeons at Johns Hopkins University. "A couple of weeks ago, we performed the first HIV-to-HIV liver transplant in the world and the first HIV-to-HIV kidney transplant in the United States," Dr. Dorry Segev said during a midday media briefing. Before 2013 and passage of the HIV Organ Policy Equity Act, this kind of medical advance would not have been possible, because it was illegal for HIV-positive patients to donate organs in the United States. The act allows HIV-positive donors to donate organs to patients infected with the AIDS-causing virus, Segev said. Until the law was changed, thousands of patients with HIV in need of organ transplants often risked death while waiting for a donated organ, he said. At the same time, "we were ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis, Organ Transplant - Rejection Prophylaxis, Organ Transplant, Graft-versus-host disease, Rejection Prophylaxis

Many Kidney Transplant Patients Land in ER Within 2 Years: Study

Posted 28 Mar 2016 by Drugs.com

THURSDAY, March 24, 2016 – More than half of kidney transplant recipients wind up in an emergency department within two years of their operation, a new study finds. The researchers looked at more than 10,500 kidney transplant patients in California, Florida and New York. The investigators found that ER visits were made by 12 percent of patients within one month, 40 percent of patients within one year and 57 percent of patients within two years. Forty-eight percent of those ER visits led to hospital admission, according to the study published online March 24 in the Clinical Journal of the American Society of Nephrology. Risk factors for ER visits included: younger age; being female; being black or Hispanic; having public insurance; having depression, diabetes or peripheral vascular disease; and use of ERs before the transplant. The findings shed light on the need to coordinate care for ... Read more

Related support groups: Diabetic Kidney Disease, Organ Transplant - Rejection Prophylaxis, Diabetic Nephropathy, Organ Transplant

Paying for Kidneys Might Boost Donor Rate, Study Says

Posted 23 Mar 2016 by Drugs.com

WEDNESDAY, March 23, 2016 – If offered $50,000, nearly three out of five Americans would part with a kidney, a new study finds. "It appears that American society is ready to accept the concept of paying kidney donors," said lead researcher Dr. Thomas Peters, an emeritus professor of surgery at the University of Florida College of Medicine, in Jacksonville. However, Peters isn't suggesting that a paid market for kidneys start anytime soon, only that the idea be studied to see if it might increase the supply of kidneys. Paying for organs is illegal under the U.S. National Organ Transplant Act. When the law was enacted, "the feeling was that altruism should prevail," Peters said. "Organs should not become a commodity, and the giving was as important as receiving. "Laws should be amended or changed, so at least pilot studies regarding this question could be carried out to see if kidney ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Organ Transplant - Rejection Prophylaxis, Peritoneal dialysis, Organ Transplant, Renal Osteodystrophy, Hyperphosphatemia of Renal Failure

Transplant From Incompatible Living Donor Boosts Kidney Patients' Survival

Posted 10 Mar 2016 by Drugs.com

WEDNESDAY, March 9, 2016 – In what experts call a possible "paradigm shift," a new study shows kidney disease patients may live far longer if they receive a transplant from an incompatible living donor rather than wait for a good match. The findings could offer another choice for kidney patients who might otherwise die waiting for a compatible deceased donor. Specifically, experts said the results offer hope to "highly sensitized" transplant candidates. That refers to patients who have a large number of immune system antibodies ready to attack a donor organ. It's common among people who've had a prior kidney transplant, according to the United Network for Organ Sharing. Patients who have had multiple blood transfusions while on dialysis, or who have been pregnant several times, can also become sensitized. Finding a compatible donor for sensitized patients is "nearly impossible," said ... Read more

Related support groups: Infections, Bacterial Infection, Organ Transplant - Rejection Prophylaxis, Organ Transplant, Organ Transplant - Rejection Reversal, Rejection Prophylaxis, Rejection Reversal

Woman Who Had 1st U.S. Uterus Transplant Loses the Organ Due to Complication

Posted 9 Mar 2016 by Drugs.com

WEDNESDAY, March 9, 2016 – The first U.S. woman to receive a transplanted uterus has had the implanted organ removed due to an unnamed "sudden complication," her doctors at the Cleveland Clinic announced Wednesday. "At this time, the circumstance of the complication is under review and more information will be shared as it becomes available," the hospital said in a statement. "There is a known risk in solid organ transplantation that the transplanted organ may have to be removed should a complication arise," the clinic added. "The medical team took all necessary precautions and measures to ensure the safety of our patient." The patient is a 26-year-old woman, identified only as Lindsey. Along with her husband Blake, she has adopted three children, but always longed to give birth to her own child. "At 16, I was told I would never have children. From that moment on," she said in a news ... Read more

Related support groups: Female Infertility, Ovulation Induction, Organ Transplant - Rejection Prophylaxis, Organ Transplant, Organ Transplant - Rejection Reversal, Primary Ovarian Failure, Rejection Prophylaxis

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