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FDA Approves Non-Opioid Medication, Lucemyra (Lofexidine), to Treat Opioid Withdrawal

Posted 17 May 2018 by Drugs.com

THURSDAY, May 17, 2018 – The U.S. Food and Drug Administration on Wednesday approved the non-opioid drug Lucemyra to help adults cope with symptoms of opioid withdrawal. The drug can help addicts boost the odds that they will be able to kick their addiction to these powerful painkillers, the FDA said. It was fast-tracked for approval under the agency's Priority Review amid ongoing concerns about ...

Non-Opioid Treatment Lucemyra (Lofexidine Hydrochloride) Approved for Opioid Withdrawal

Posted 17 May 2018 by Drugs.com

THURSDAY, May 17, 2018 – Lucemyra (lofexidine hydrochloride) has been approved by the U.S. Food and Drug Administration to treat symptoms of opioid withdrawal. Withdrawal from an opioid painkiller can trigger symptoms including anxiety, agitation, sleep problems, muscle aches, sweating, nausea, diarrhea and drug craving. To prevent such symptoms, doctors typically recommend slow withdrawal from ...

FDA Approves Lucemyra (lofexidine hydrochloride) as the First Non-Opioid Treatment for Management of Opioid Withdrawal Symptoms

Posted 17 May 2018 by Drugs.com

May 16, 2018 – The U.S. Food and Drug Administration today approved Lucemyra (lofexidine hydrochloride) for the mitigation of withdrawal symptoms to facilitate abrupt discontinuation of opioids in adults. While Lucemyra may lessen the severity of withdrawal symptoms, it may not completely prevent them and is only approved for treatment for up to 14 days. Lucemyra is not a treatment for opioid ...

Hit Hard by Opioid Crisis, Appalachian States Expand Clean-Needle Programs

Posted 11 May 2018 by Drugs.com

FRIDAY, May 11, 2018 – In 2013, there was just one clean-needle program in all of West Virginia, Kentucky and North Carolina, and the latter two states had laws banning such programs. Fast-forward four years: All of those laws have now been overturned and the number of "syringe services programs" available to help addicts has risen to over 50 across the three states, researchers report. ...

Programs That Monitor Opioid Painkillers May Drive Some to Heroin

Posted 8 May 2018 by Drugs.com

MONDAY, May 7, 2018 – Prescription drug monitoring programs are touted as a way to reduce overdoses from opioid painkillers, but they might have the unintended effect of increasing heroin overdose deaths, researchers say. They reviewed 17 studies that assessed the impact of these programs and found that 10 of them linked the programs to reductions in opioid overdose deaths. But three studies ...

Doctors Curbing First-Time Prescriptions for Opioids

Posted 13 Apr 2018 by Drugs.com

THURSDAY, April 12, 2018 – Although the opioid epidemic continues to rage in America, promising new data show that first-time opioid painkiller prescription rates have slowed in recent years. The researchers also discovered that people taking medications called benzodiazepines – used to treat anxiety, panic attacks and mental conditions associated with chronic pain – were more likely to ...

Addicts Should Be Trained to Give OD Antidote, Naloxone, Study Finds

Posted 5 Apr 2018 by Drugs.com

THURSDAY, April 5, 2018 – Frequent opioid users may be the best candidates for training to reverse overdoses in other users, researchers say. The U.S. opioid crisis has led many public health departments and community groups to begin training users on the use of the opioid-blocker naloxone. In a new study, a team from Johns Hopkins Bloomberg School of Public Health in Baltimore examined ways to ...

Certain Teens More Likely to Get Hooked on Opioids

Posted 12 Mar 2018 by Drugs.com

MONDAY, March 12, 2018 – Teenagers with any mental health problem are more prone to painkiller dependence after receiving a prescription opioid, a new study finds. The odds of progressing to long-term opioid therapy can double, triple or more, depending on the kid's diagnosis and the other drugs prescribed to treat their disorder, the researchers said. The findings mirror earlier studies showing ...

ER Visits for Opioid Overdoses Soaring: CDC

Posted 6 Mar 2018 by Drugs.com

TUESDAY, March 6, 2018 – America's opioid epidemic is escalating at breakneck speed, with tens of thousands of overdose victims spilling into the nation's emergency rooms seeking lifesaving treatment, a new government report shows. Emergency room visits for opioid overdoses increased nationwide and across all demographic groups between July 2016 and September 2017, according to ER records ...

Some Pain Patients Can Cut Opioid Dose and Still Get Relief

Posted 21 Feb 2018 by Drugs.com

WEDNESDAY, Feb. 21, 2018 – Some potentially good news for folks taking opioids for chronic pain: It's possible to slowly reduce the dosage without increasing discomfort, new research suggests. That's even true for people who've taken the drugs for a long time. One patient in the new study had used opioids for 38 years, the researchers said. "For some people, long-term opioids are necessary, but ...

Herbal Drug Kratom Contains Opioids, FDA Says

Posted 7 Feb 2018 by Drugs.com

WEDNESDAY, Feb. 7, 2018 – The popular botanical drug kratom essentially is an opioid, the U.S. Food and Drug Administration declared Tuesday. Nearly all of kratom's major compounds bind to opioid receptors in the human brain, and two of the top five most prevalent compounds activate those receptors, FDA Commissioner Scott Gottlieb said in a statement. In addition, there have been 44 reported ...

Responding to Opioid Crisis, FDA Puts More Restrictions on Imodium

Posted 30 Jan 2018 by Drugs.com

TUESDAY, Jan. 30, 2018 – Increasingly, people addicted to opioid painkillers are using dangerously high doses of the diarrhea drug Imodium (loperamide), either to get high or to help ease withdrawal. So, on Tuesday the U.S. Food and Drug Administration said it's putting new restrictions on the packaging of the medication, dubbed by some as "the poor man's methadone." "When higher than ...

FDA, FTC Warn Companies for Selling Illegal, Unapproved Opioid Cessation Products Using Deceptive Claims

Posted 25 Jan 2018 by Drugs.com

January 24, 2018 – The U.S. Food and Drug Administration and the Federal Trade Commission today posted joint warning letters to the marketers and distributors of 12 opioid cessation products, for illegally marketing unapproved products with claims about their ability to help in the treatment of opioid addiction and withdrawal. “The FDA is increasingly concerned with the proliferation of products ...

Tamper-Resistant Opioids May Not Ease Addiction Crisis: Study

Posted 11 Jan 2018 by Drugs.com

THURSDAY, Jan. 11, 2018 – Tamper-resistant opioid pills – one attempt to curb prescription painkiller abuse – aren't stopping overuse and overdosing, at least in Australia, new research shows. "This formulation was developed with the specific aim of reducing tampering, targeting behaviors such as injection or snorting," said the study's lead author, Briony Larance. But there was also the hope ...

The Opioid Crisis' Hidden Victims: Children in Foster Care

Posted 9 Jan 2018 by Drugs.com

MONDAY, Jan. 8, 2018 – As the opioid epidemic continues to grip the United States, the toll on the littlest victims – the children of addicts – is mounting, new research shows. "There are many negative aspects to the opioid crisis, but its effect on children is arguably one of the worst," said study author Troy Quast, an associate professor at the University of South Florida's College of ...

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