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Related terms: Migraine Headache, Hemiplegic Migraine, Complicated Migraine, Basilar-Type Migraine, Basilar Artery Migraine

Homing In on the Genetics of Migraine

Posted 27 Jun 2016 by Drugs.com

SUNDAY, June 26, 2016 – An international team of scientists has identified dozens of new genetic variants associated with migraine headaches. The researchers say their findings could lead to new treatments. Most of the variants are in or close to genes involved in circulatory system regulation. This supports the theory that abnormal blood vessel function in the brain is an important factor in migraines, the investigators said. "These genetic findings are the first concrete step towards developing personalized, evidence-based treatments for this very complex disease. We doctors have known for a long time that migraine patients differ from each other and the drugs that work for some patients are completely inefficient for others," said John-Anker Zwart, of Oslo University Hospital in Norway, who participated in the research. "In the future, we hope that this information can be utilized ... Read more

Related support groups: Headache, Migraine, Migraine Prevention, Migraine Prophylaxis, New Daily Persistent Headache, Diagnosis and Investigation, Head Imaging

Vitamin Deficiencies Common in Young Migraine Sufferers

Posted 10 Jun 2016 by Drugs.com

FRIDAY, June 10, 2016 – Many young people who suffer from migraines have vitamin deficiencies, new research finds. "Further studies are needed to elucidate whether vitamin supplementation is effective in migraine patients in general, and whether patients with mild deficiency are more likely to benefit from supplementation," said lead study author Dr. Suzanne Hagler in a Cincinnati Children's Hospital Medical Center news release. She is a headache medicine fellow in the hospital's division of neurology. The study included children, teens and young adult migraine patients who were treated at Cincinnati Children's Headache Center. A high percentage of them had mild deficiencies in vitamin D, riboflavin and coenzyme Q10 – a vitamin-like substance used to produce energy for cell growth and maintenance, the researchers said. Many of the patients were prescribed preventive migraine ... Read more

Related support groups: Migraine, Migraine Prevention, Vitamin D Deficiency, Vitamin/Mineral Supplementation and Deficiency, Migraine Prophylaxis, Caltrate 600 with D, Riboflavin, Os-Cal 500 with D, Calcium/Vitamin D, Citracal + D, Oysco 500 with D, Vitamin B2, Oyster Shell Calcium, Citracal Creamy Bites, Calcet, Calcium 600 D, Calcarb with D, Citracal Petites, Dical-D, B2-400

Experimental Drug Acts Fast Against Chronic Migraine

Posted 8 Jun 2016 by Drugs.com

WEDNESDAY, June 8, 2016 – An experimental drug may bring fast relief to people with debilitating chronic migraines, a new study finds. Preliminary trials had already found that the drug – dubbed TEV-48125 – can help prevent migraine attacks in people who've suffered long-term with headaches. Now, the new findings suggest that it starts working within three to seven days of the first injection, researchers reported. "To my knowledge, that's the fastest separation ever demonstrated in chronic migraine," said lead researcher Dr. Marcelo Bigal, of Teva Pharmaceuticals, the company developing TEV-48125. The term "separation" refers to the point at which patients on TEV-48125 started to improve, compared to patients given a placebo (an inactive treatment). TEV-48125 is one of a new class of drugs being developed to prevent migraines. The medications are all antibodies that block a chemical ... Read more

Related support groups: Migraine, Migraine Prevention, Migraine Prophylaxis, Diagnosis and Investigation, Trochleitis

FDA Medwatch Alert: Zecuity (sumatriptan) Migraine Patch: Drug Safety Communication - FDA Evaluating Risk of Burns and Scars

Posted 2 Jun 2016 by Drugs.com

ISSUE: FDA is investigating the risk of serious burns and potential permanent scarring with the use of Zecuity (sumatriptan iontophoretic transdermal system) patch for migraine headaches. Since marketing of the Zecuity patch began in September 2015, a large number of patients have reported they experienced burns or scars on the skin where the patch was worn. The reports included descriptions of severe redness, pain, skin discoloration, blistering, and cracked skin. As a result, FDA is investigating these serious adverse events to determine whether future regulatory action is needed, and will update the public with new information when the FDA review is complete. BACKGROUND: The Zecuity patch contains the active ingredient sumatriptan, a prescription medicine used to treat acute migraine headaches in adults. The patch delivery system is designed to deliver a dose of medicine by way of a ... Read more

Related support groups: Migraine, Sumatriptan, Zecuity

Exploring the Link Between Estrogen and Migraines

Posted 1 Jun 2016 by Drugs.com

WEDNESDAY, June 1, 2016 – Researchers are getting a better understanding of the link between estrogen levels and migraine headaches in women. A new study finds that for women who get these intense headaches, levels of the hormone estrogen drop more rapidly in the days before menstruation than in women without the headaches. "These results suggest that a 'two-hit' process may link estrogen withdrawal to menstrual migraine," said study author Dr. Jelena Pavlovic, of the Albert Einstein College of Medicine/Montefiore Medical Center in New York City. "More rapid estrogen decline may make women vulnerable to common triggers for migraine attacks such as stress, lack of sleep, foods and wine." Researchers looked at urine samples of 114 women with migraines and 223 women without migraines, average age 47. Estrogen levels among those with migraines dropped 40 percent in the days just before ... Read more

Related support groups: Migraine, Estradiol, Migraine Prevention, Premarin, Ethinyl Estradiol, Estrace, Migraine Prophylaxis, Vagifem, Vivelle, Estrace Vaginal Cream, Climara, Estring, Vivelle-Dot, Estradiol Patch, Premarin Vaginal, Minivelle, Evamist, Cenestin, Enjuvia, Femring

Women With Migraine May Face Higher Threat of Heart Disease, Stroke

Posted 1 Jun 2016 by Drugs.com

TUESDAY, May 31, 2016 – Women who suffer from migraine headaches may have a slightly increased risk of heart disease or stroke, a new study suggests. "Migraine should be considered a marker for increased risk of cardiovascular disease, at least in women," said lead researcher Dr. Tobias Kurth, director of the Institute of Public Health at Charite-Universitatsmedizin in Berlin, Germany. But, Kurth cautioned that this study can't prove that migraines cause heart attack or stroke, only that they may make these events more likely. Also, men may be similarly affected. "We have no reason to believe that this is limited to women," Kurth said. Migraines are headaches marked by intense throbbing or pulsing, often accompanied by nausea, vomiting and sensitivity to light and sound. They had previously been linked to an increased risk for stroke, but this new study also ties them to possible heart ... Read more

Related support groups: Migraine, Ischemic Stroke, Heart Attack, Migraine Prevention, Migraine Prophylaxis, Transient Ischemic Attack, Myocardial Infarction, Intracranial Hemorrhage, Trochleitis

Migraines Take Toll on Spouse

Posted 31 May 2016 by Drugs.com

TUESDAY, May 31, 2016 – If you suffer from migraines, your spouse probably suffers, too. That's the conclusion of researchers who surveyed more than 4,000 people with the debilitating headaches and their spouses/domestic partners. "This study highlights the significant burden that migraine can have on a wide range of family activities, parenting responsibilities, spousal relationships and family finances," said lead author Dawn Buse, director of behavioral medicine at Montefiore Headache Center in New York City. More than two out of five people with migraines and 23 percent of their spouses/partners said they believed the person with migraines would be a better parent if they did not have the condition. About half of the people with migraines had missed at least one family activity in the past month because of a migraine, the study found. About one-third of migraine sufferers and 21 ... Read more

Related support groups: Migraine, Ibuprofen, Naproxen, Meloxicam, Migraine Prevention, Diclofenac, Advil, Voltaren, Aleve, Mobic, Fioricet, Motrin, Excedrin, Indomethacin, Imitrex, Migraine Prophylaxis, Tylenol PM, Sumatriptan, Maxalt, Toradol

Antidepressants Not Just for Depression Any More

Posted 24 May 2016 by Drugs.com

TUESDAY, May 24, 2016 – Doctors prescribe antidepressants for a wide range of medical problems other than depression, apparently fueling the boom in sales of these medications, researchers report. Depression accounts for only a little more than half the antidepressant prescriptions issued by Quebec physicians during the past decade, the Canadian study found. Doctors also issued antidepressants to treat anxiety, insomnia, chronic pain, panic disorders, fibromyalgia, migraine, obsessive-compulsive disorders, and a host of other "off-label" conditions for which the drugs are not approved, according to the report. Two out of every three non-depression prescriptions for antidepressants were handed out under an off-label purpose, the findings showed. "The thing that's of concern here is that when prescribing for conditions other than depression, often these are for indications such as ... Read more

Related support groups: Pain, Depression, Anxiety, Generalized Anxiety Disorder, Headache, Panic Disorder, Anxiety and Stress, Lexapro, Fibromyalgia, Sleep Disorders, Zoloft, Wellbutrin, Cymbalta, Migraine, Effexor, Insomnia, Prozac, Celexa, Citalopram, Paxil

Health Tip: Have Headaches? Speak to Your Doctor

Posted 24 May 2016 by Drugs.com

-- A headache is generally recognized as having pain or discomfort anywhere in the head, scalp or neck. It can be a symptom of everything from minor stress to a life-threatening stroke. Learning all you can about your condition is a first step on the road to treatment and prevention. The National Headache Foundation suggests: Learn as much a possible, such as what's probably causing your headaches and how to prevent them. Focus on the most important questions, and get answers to less important questions later. Voice any concerns or fears about your headaches to your doctor. If you don't understand something, ask the doctor for an explanation. Read more

Related support groups: Headache, Migraine, Ibuprofen, Naproxen, Meloxicam, Migraine Prevention, Diclofenac, Advil, Voltaren, Aleve, Mobic, Fioricet, Motrin, Excedrin, Cluster Headaches, Indomethacin, Imitrex, Migraine Prophylaxis, Tylenol PM, Sumatriptan

Giving the 'Green Light' to Migraine Relief

Posted 17 May 2016 by Drugs.com

TUESDAY, May 17, 2016 – A new study sheds light – literally – on a potential means of easing migraine pain. Researchers in Boston exposed 69 migraine patients to different colors of light. They found that while blue light exacerbated headache pain, a narrow spectrum of low-intensity green light significantly reduced light sensitivity. In some cases, this green light also reduced migraine pain by about 20 percent, the researchers found. They noted that migraine headache affects nearly 15 percent of people worldwide, and a frequent symptom of migraine is light sensitivity, also known as photophobia. "Although photophobia is not usually as incapacitating as headache pain itself, the inability to endure light can be disabling," study author Rami Burstein, of Beth Israel Deaconess Medical Center in Boston, said in a medical center news release. "More than 80 percent of migraine attacks ... Read more

Related support groups: Migraine, Celebrex, Fioricet, Excedrin, Imitrex, Tylenol PM, Sumatriptan, Maxalt, Fiorinal, Seasonal Affective Disorder, Excedrin Migraine, Cafergot, Relpax, Treximet, Zomig, Advil PM, Midrin, Vioxx, Ergotamine, Celecoxib

Doctors Issue Call to Combat Climate Change

Posted 18 Apr 2016 by Drugs.com

MONDAY, April 18, 2016 – Climate change is already harming people's health by promoting illnesses linked to warmer temperatures and changing weather patterns, a leading group of U.S. doctors says in a new position paper. As a result, the American College of Physicians (ACP) is calling for "aggressive, concerted" action to fight climate change by curbing man-made greenhouse gas emissions. Respiratory illnesses, heat stroke and infectious diseases like Zika virus, dengue fever and cholera are flourishing as global temperatures rise, said Dr. Wayne Riley, president of the college. "Our climate is already changing and people are already being harmed. If we don't begin to address climate change, we're going to see more and more manifestations of these health problems," Riley said. "There is clear, compelling scientific consensus that climate change is real," he added. "There is no dispute." ... Read more

Related support groups: Depression, Anxiety and Stress, Migraine, Allergies, Asthma, Major Depressive Disorder, Post Traumatic Stress Disorder, Sinusitis, Chronic Obstructive Pulmonary Disease, Bronchitis, Migraine Prevention, Pneumonia, Asthma - Maintenance, Cold Symptoms, Chronic Obstructive Pulmonary Disease, Maintenance, Upper Respiratory Tract Infection, Dyspnea, Migraine Prophylaxis, Psychiatric Disorders, Dysthymia

Botox Can Be Used for Chronic Migraine, Experts Say

Posted 18 Apr 2016 by Drugs.com

MONDAY, April 18, 2016 – Botox is a safe and effective treatment for chronic migraine and three other neurological disorders, an updated guideline from the American Academy of Neurology says. Long used to smooth wrinkles, botulinum toxin is made by a type of bacteria. The toxin blocks the release of substances at nerve endings, reducing muscle contraction and the transmission of pain signals, the researchers explained. The authors of the updated guideline reviewed scientific studies on the four preparations of botulinum toxin available in the United States. They concluded that the treatment is generally safe and effective for four neurological conditions: chronic migraine, spasticity in adults, cervical dystonia and blepharospasm. Chronic migraine is defined as having migraines 15 or more days a month, the study authors explained. Spasticity in adults is muscle tightness that ... Read more

Related support groups: Migraine, Migraine Prevention, Migraine Prophylaxis, Facial Wrinkles, Cervical Dystonia, Chronic Spasticity, Blepharospasm, Spasticity, Spinal Spasticity, Upper Limb Spasticity, Lower Limb Spasticity, Botulinum Toxin Type B, Myobloc

What Women Should Do to Guard Against Vision Loss

Posted 12 Apr 2016 by Drugs.com

TUESDAY, April 12, 2016 – Women are a majority of the 4.4 million Americans over age 40 who are visually impaired or blind, Prevent Blindness says. The national organization has declared April as Women's Eye Health and Safety Awareness Month, and has outlined several things women need to know about vision and eye health. The group said women are at greater risk than men for vision loss from such eye diseases as cataracts, glaucoma and macular degeneration, as well as a condition called dry eye, which is more common after menopause. Pregnancy can cause dry eyes, puffy eyelids and refractive changes that may show up as blurred or double vision. Pregnant women's vision may also be affected by migraine headaches, diabetes and high blood pressure, according to Prevent Blindness. The organization also warns that some glaucoma medications may harm a fetus, and advises pregnant women to ... Read more

Related support groups: High Blood Pressure, Diabetes, Type 2, Migraine, Hypertension, Eye Conditions, Hot Flashes, Menopausal Disorders, Glaucoma, Diabetes, Type 1, Eye Dryness/Redness, Cataract, Postmenopausal Symptoms, Pre-Diabetes, Perimenopausal Symptoms, Diabetes Mellitus, Visual Defect/Disturbance

Severe Migraines Linked to Complications During Pregnancy, Childbirth

Posted 11 Mar 2016 by Drugs.com

FRIDAY, March 11, 2016 – Severe migraines are associated with an increased risk of complications during pregnancy and childbirth, especially among older women, new research suggests. "The results of this study were of particular interest because more than half of the pregnant women with migraine experienced some type of adverse birth outcome, suggesting that these pregnancies should be considered high risk," study author Dr. Matthew Robbins, said in a Montefiore Medical Center news release. Robbins is director of inpatient services at Montefiore Headache Center. He's also chief of neurology at the Jack D. Weiler Hospital of Montefiore in New York City. It's important to note that the study only found a link between women with severe migraines and pregnancy and delivery complications. The study wasn't designed to prove that having or treating migraines caused these problems. The study ... Read more

Related support groups: Migraine, Migraine Prevention, Migraine Prophylaxis, Premature Labor, Labor Induction, Postpartum Bleeding, Cervical Ripening, Labor Pain, Cesarean Section, Labor and Delivery including Augmentation

Emotional Abuse During Childhood Linked to Adult Migraine Risk

Posted 3 Mar 2016 by Drugs.com

WEDNESDAY, March 2, 2016 – Adults who suffered emotional abuse as children may have an increased risk of migraines, but such a link wasn't seen with physical or sexual abuse, researchers are reporting. "Emotional abuse showed the strongest link to increased risk of migraine," study author Dr. Gretchen Tietjen, from the University of Toledo in Ohio, said in an American Academy of Neurology news release. "Childhood abuse can have long-lasting effects on health and well-being." But while the study showed an association between childhood emotional abuse and migraine, it did not prove cause and effect, Tietjen noted. Of the nearly 14,500 young adults in the study, approximately 14 percent had been diagnosed with migraines. About 47 percent said they were emotionally abused during childhood, 18 percent said they were physically abused and 5 percent said they were sexually abused. Sixty-one ... Read more

Related support groups: Migraine, Migraine Prevention, Migraine Prophylaxis, Diagnosis and Investigation, Head Imaging

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