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Lower Limb Spasticity News

Lower Back Injuries Plague Many Athletes

Posted 7 days ago by Drugs.com

FRIDAY, July 14, 2017 – Back injuries are common, especially among competitive athletes. Nearly 1 in 3 athletes playing professional or varsity-level sports experiences a back injury, a research review finds. "Competitive players stress their lumbar [lower] spine for hundreds of hours a month, thereby predisposing themselves to specific injuries that should be recognized by health care practitioners," said lead author Dr. Wellington Hsu, an orthopedic spine surgeon at Northwestern Memorial Hospital in Chicago. The human spine has 24 bones, or vertebrae. They're stacked on top of each other, separated by flat, round cushioning disks. When people walk or run, these disks absorb shock, the authors explained. Athletes are at risk for problems involving their back bones and discs, particularly if they start intense training regimens when they are between 10 and 24 years old, the researchers ... Read more

Related support groups: Back Pain, Sciatica, Herniated Disc, Scoliosis, Fracture, bone, Spondyloarthritis, Compression Fracture of Vertebral Column, Radiculopathy, Lower Limb Spasticity, Prevention of Fractures

Breast-Feeding May Lower Risk of MS, Study Says

Posted 11 days ago by Drugs.com

WEDNESDAY, July 12, 2017 – Women with a longer history of breast-feeding may be less likely to develop multiple sclerosis than mothers who skip breast-feeding or nurse for briefer periods, a new study suggests. Researchers compared nearly 400 women with MS or its precursor, known as clinically isolated syndrome (CIS), with a similar healthy group. They found that mothers who had breast-fed one or more children for a total of 15 months or longer were 53 percent less likely to develop MS or CIS than those with zero to four months of total breast-feeding. "No one has shown before that breast-feeding could have a prolonged benefit on the mother's immune system," said study author Dr. Annette Langer-Gould. She's a research scientist in neurology at Kaiser Permanente in Pasadena, Calif. "This is one more piece of evidence that women who want to breast-feed should be supported to do so," ... Read more

Related support groups: Birth Control, Contraception, Multiple Sclerosis, Delivery, Chronic Spasticity, Vitamin/Mineral Supplementation during Pregnancy/Lactation, Spasticity, Upper Limb Spasticity, Cesarean Section, Lower Limb Spasticity, Labor and Delivery including Augmentation, Lactation Augmentation, Spinal Spasticity

Ipsen Announces FDA approval of Dysport (abobotulinumtoxinA) for the Treatment of Lower Limb Spasticity in Adults

Posted 21 Jun 2017 by Drugs.com

June 16, 2017 – Ipsen (Euronext: IPN; ADR: IPSEY) (Ipsen) today announced that the U.S. Food and Drug Administration (FDA) has expanded the approved use of Dysport (abobotulinumtoxinA) for injection for the treatment of spasticity in adults, based on its supplemental Biologics License Application (sBLA) in lower limb spasticity. In July 2015, Dysport® was approved for the treatment of upper limb spasticity in adults. In July 2016, Dysport® was approved to treat pediatric patients with lower limb spasticity aged two and older, making it the first and only botulinum toxin that the FDA approved for this indication. In a Phase III, multi-center, prospective, double-blind, randomized placebo-controlled study, adult patients treated with Dysport® following a stroke or traumatic brain injury showed improvement in muscle tone at the ankle joint, measured by the mean change from baseline on the ... Read more

Related support groups: Spasticity, Dysport, Lower Limb Spasticity, Abobotulinumtoxina

MS-Related Brain Changes May Affect Social Skills

Posted 1 Jun 2017 by Drugs.com

THURSDAY, June 1, 2017 – Subtle brain changes may explain why some people with multiple sclerosis (MS) lose their ability to interpret clues about what other people are thinking and feeling, a new study suggests. Until now, there has been little study of the way MS affects the so-called "social brain." Portuguese researchers wanted to learn why some people with MS develop a social disconnect that can hurt relationships and breed isolation. It doesn't happen to everyone with MS, but experts agree that it's a big deal for those who experience it. "It could interfere with all spheres of social interaction," said lead researcher Dr. Sonia Batista, a neurologist at the University of Coimbra in Portugal. "The ability to interpret other people's feelings and intentions may influence people's ability to maintain a job and their relationships with family and friends," said Batista. That's ... Read more

Related support groups: Anxiety, Generalized Anxiety Disorder, Anxiety and Stress, Social Anxiety Disorder, Multiple Sclerosis, Performance Anxiety, Chronic Spasticity, Spasticity, Diagnosis and Investigation, Upper Limb Spasticity, Spinal Spasticity, Lower Limb Spasticity

Immune-Based Therapy Shows Early Promise Against MS

Posted 21 Apr 2017 by Drugs.com

THURSDAY, April 20, 2017 – An experimental immune-system therapy appears safe for people with progressive forms of multiple sclerosis. And it may ease symptoms in some, a preliminary study suggests. The findings are based on just six patients, and the Australian researchers stressed that a lot of work still lies ahead. But they were encouraged that this new approach to MS had no major side effects. In addition, three of the six patients showed symptom improvements, including reduced fatigue and better mobility. It's not clear, however, what to make of those improvements, said Bruce Bebo, executive vice president of research for the National Multiple Sclerosis Society. The study was a "phase 1" trial, meaning it was designed only to test the therapy's safety. "Based on this very preliminary study, the therapy appears safe," said Bebo, who was not involved in the research. "But I'd be ... Read more

Related support groups: Multiple Sclerosis, Chronic Spasticity, Spasticity, Diagnosis and Investigation, Upper Limb Spasticity, Spinal Spasticity, Lower Limb Spasticity

Ocrevus Approved to Treat Severe Form of Multiple Sclerosis

Posted 29 Mar 2017 by Drugs.com

WEDNESDAY, March 29, 2017 – The injected drug Ocrevus (ocrelizumab) has been approved by the U.S. Food and Drug Administration to treat adults with primary progressive multiple sclerosis (PPMS) and relapsing forms of the disease, the agency said Wednesday in a news release. MS is an inflammatory autoimmune disease of the central nervous system, characterized by periods of active symptoms (relapses) and recovery periods (remission). Disrupting communication between the brain and the rest of the body, it's among the most common neurological causes of disability in young adults. More women than men are diagnosed, typically between ages 20 and 40. About 15 percent of people with MS have PPMS, the FDA said, citing the U.S. Centers for Disease Control and Prevention. In clinical trials, upper respiratory infection was the most common side effect of Ocrevus among users with either PPMS or ... Read more

Related support groups: Multiple Sclerosis, Chronic Spasticity, Spasticity, Ocrevus, Upper Limb Spasticity, Lower Limb Spasticity, Spinal Spasticity

FDA-OK'd Drug Offers Hope to Sickest MS Patients

Posted 29 Mar 2017 by Drugs.com

WEDNESDAY, March 29, 2017 – A new multiple sclerosis drug approved by the U.S. Food and Drug Administration late Tuesday offers hope to patients with the most severe form of the progressive disease. The intravenous drug, made by Genentech, is called ocrelizumab (Ocrevus). Given every six months, it worked best for patients with relapsing multiple sclerosis (MS) – the most common form of the disease, the FDA reported. But Ocrevus also appeared to slow progression of a more severe type of the disease, called primary progressive MS. "If the side effect profile continues to hold up ... I think ocrelizumab will become the leading MS therapy," said Dr. Steven Galetta, chairman of neurology at NYU Langone Medical Center in New York City. He wasn't involved in the clinical trials that led to the drug's approval. "The drug offers the first option for patients with primary progressive MS," he ... Read more

Related support groups: Multiple Sclerosis, Rebif, Chronic Spasticity, Spasticity, Ocrevus, Upper Limb Spasticity, Spinal Spasticity, Lower Limb Spasticity

Controversial MS Treatment Seems Ineffective

Posted 8 Mar 2017 by Drugs.com

WEDNESDAY, March 8, 2017 – An invasive multiple sclerosis treatment called liberation therapy is not only costly, it's also ineffective, new research contends. Since 2009, thousands of multiple sclerosis (MS) patients have undergone the controversial treatment. Liberation therapy involves opening up narrowed veins from the brain and spinal cord. However, many specialists have had doubts about the success of the procedure, the study authors said in background notes. In this Canadian study, 49 MS patients underwent liberation therapy and 55 other patients received a sham procedure. One year later, brain scans, doctors' reports and patient self-assessments of MS symptoms found no differences between the two groups of patients. "We hope these findings, coming from a carefully controlled, 'gold standard' study, will persuade people with MS not to pursue liberation therapy," said Dr. Anthony ... Read more

Related support groups: Multiple Sclerosis, Autoimmune Disorders, Chronic Spasticity, Caltrate 600 with D, Spasticity, Upper Limb Spasticity, Calcium/Vitamin D, Citracal + D, Citracal Petites, Oysco 500 with D, Calcet, Calcium 600 D, Lower Limb Spasticity, Calcarb with D, Spinal Spasticity, Oyster Shell Calcium, Citracal Creamy Bites, Osteocit D Plus, Dical Captabs, Oysco D

Stem Cell Transplants May Help Some With Multiple Sclerosis

Posted 20 Feb 2017 by Drugs.com

MONDAY, Feb. 20, 2017 – Stem cell transplants may halt the progression of aggressive multiple sclerosis (MS) in nearly half of those with the debilitating disease, but picking the right patients for the treatment is key, a new study suggests. Specifically, younger patients with a relapsing form of MS who were not severely disabled and who hadn't found relief with other treatments fared better than others over five years, the international team of researchers found. However, in some cases the treatment proved fatal, the researchers reported. "Stem cell transplantation cannot be considered a cure for MS. However, it can be considered a concrete option for patients showing aggressive MS who have not responded to approved treatments," said study co-author Dr. Riccardo Saccardi. He's from the cell therapy and transfusion medicine unit at Careggi University Hospital in Florence, Italy. Using ... Read more

Related support groups: Multiple Sclerosis, Chronic Spasticity, Spasticity, Diagnosis and Investigation, Upper Limb Spasticity, Spinal Spasticity, Lower Limb Spasticity

U.S. Report Cites the Good and Bad on Marijuana

Posted 12 Jan 2017 by Drugs.com

THURSDAY, Jan. 12, 2017 – Current medical science has proven there are legitimate medical uses for marijuana and cannabis-derived drugs, a new report from the National Academy of Sciences states. Conclusive or substantial scientific evidence has shown that marijuana products are effective at treating chronic pain, calming muscle spasms caused by multiple sclerosis, and easing nausea from chemotherapy, the report said. However, there's little to no evidence supporting any of the other numerous health claims related to marijuana, the report said. And there's a downside as well – marijuana use comes with a host of potential health risks, whether someone is using the drug medicinally or recreationally, according to the report. The report calls on government to ease regulations that hamper research into marijuana, so scientists can sort the wheat from the chaff when it comes to medical ... Read more

Related support groups: Pain, Anxiety, Anxiety and Stress, Muscle Spasm, Chronic Pain, Muscle Pain, Social Anxiety Disorder, Multiple Sclerosis, Schizophrenia, Schizoaffective Disorder, Breakthrough Pain, Chronic Spasticity, Cannabis, Spasticity, Spinal Spasticity, Lower Limb Spasticity

New MS Drug Shows 'Breakthrough' Promise for Advanced Disease

Posted 22 Dec 2016 by Drugs.com

THURSDAY, Dec. 22, 2016 – A new drug slows the progress of multiple sclerosis, including an advanced form of the degenerative nerve disease for which there currently is no treatment, according to a pair of new clinical trials. One MS specialist called the intravenous drug, ocrelizumab, a "breakthrough." Ocrelizumab reduced the advance of MS-related disability by 24 percent in people with primary progressive MS compared to a placebo, results from one clinical trial show. Researchers compared ocrelizumab against a placebo, or dummy drug, because there's no approved treatment available for primary progressive MS. This form affects about 15 percent of MS patients, said Dr. Stephen Hauser, chair of neurology at the University of California, San Francisco. "It does represent new hope for people with progressive MS," said Hauser, who worked on both reports. Ocrelizumab also proved superior in ... Read more

Related support groups: Multiple Sclerosis, Chronic Spasticity, Spasticity, Upper Limb Spasticity, Lower Limb Spasticity, Spinal Spasticity

Specially Designed Video Game Might Ease 'Phantom Limb' Pain

Posted 2 Dec 2016 by Drugs.com

THURSDAY, Dec. 1, 2016 – Amputees who experience what is known as phantom limb pain may benefit from playing a virtual reality game that simulates the movement of missing limbs, a small study suggests. "Phantom limb pain is a difficult condition to treat that can seriously hinder patients' quality of life," said study lead author Max Ortiz Catalan. He is an assistant professor at Sweden's Chalmers University of Technology. Phantom limb pain occurs when amputees feel painful sensations that appear to be coming from limbs that no longer exist. In about one-third of cases, the pain can lead to poor mental health and worsening disability, the study authors noted. "The results from our study suggest that it may be useful to 'exercise' the phantom limb," Catalan explained. "Our treatment offers an engaging way to do this while also providing a non-invasive and non-pharmacological treatment, ... Read more

Related support groups: Neuropathic Pain, Periodic Limb Movement Disorder, Spinal Cord Trauma, Autonomic Neuropathy, Central Nervous System Disorders, Upper Limb Spasticity, Lower Limb Spasticity

Could Low Vitamin D Levels at Birth Mean Higher MS Risk?

Posted 2 Dec 2016 by Drugs.com

THURSDAY, Dec. 1, 2016 – Newborns with low levels of vitamin D may have higher odds of developing multiple sclerosis (MS) later in life, new research suggests. Vitamin D deficiency is common among the general population, including pregnant women. But the researchers said it's too soon to routinely recommend "sunshine vitamin" supplements for mothers-to-be. "The study does not prove that increasing vitamin D levels reduces the risk of MS. Further studies are needed to confirm our results," said study leader Dr. Nete Munk Nielsen, a researcher at the Statens Serum Institute in Copenhagen, Denmark. About 2.5 million people worldwide have MS. It's a chronic disease of the central nervous system characterized by damage to myelin, the fatty substance coating nerve fibers. MS symptoms vary, but can include walking difficulties, fatigue, numbness and vision problems. A growing body of evidence ... Read more

Related support groups: Multiple Sclerosis, Vitamin D Deficiency, Vitamin/Mineral Supplementation and Deficiency, Delivery, Chronic Spasticity, Vitamin/Mineral Supplementation during Pregnancy/Lactation, Caltrate 600 with D, Spasticity, Vitamin D Insufficiency, Calcium/Vitamin D, Upper Limb Spasticity, Citracal + D, Citracal Petites, Oysco 500 with D, Calcet, Prematurity/Underweight in Infancy, Calcium 600 D, Calcarb with D, Lower Limb Spasticity, Labor and Delivery including Augmentation

MS Symptoms May Develop Earlier in Darker, Cooler Climes

Posted 4 Nov 2016 by Drugs.com

THURSDAY, Nov. 3, 2016 – The farther from the Equator someone with multiple sclerosis lives, the earlier symptoms begin, a new study finds. MS is a progressive disease affecting the central nervous system. Although symptoms vary, they often include fatigue, dizziness, weakness, numbness or tingling, trouble walking and vision problems. The cause of MS is thought to be an interplay of genetic and environmental factors, including latitude and/or exposure to sunlight and vitamin D levels. But it wasn't known if latitude – the distance north or south of the Equator – affected the age when symptoms start. To examine the issue, Dr. Bruce Taylor, a professor at Menzies Institute for Medical Research at the University of Tasmania, and colleagues analyzed data from more than 22,000 MS patients in Australia and 20 countries in Europe, North and South America and Asia. According to the new ... Read more

Related support groups: Multiple Sclerosis, Chronic Spasticity, Spasticity, Upper Limb Spasticity, Lower Limb Spasticity, Spinal Spasticity

Powerful MS Drug Used Early May Reverse Some Disability

Posted 14 Oct 2016 by Drugs.com

FRIDAY, Oct. 14, 2016 – A multiple sclerosis drug usually reserved for people in the late stages of the disease seems to offer long-term remission in newly diagnosed patients, researchers report. Because of serious side effects, the drug – Lemtrada (alemtuzumab) – is approved in the United States only for patients who have failed other treatments. But the authors of a new study believe giving it early may slow and even reverse some disease-related disability. "The expectation in MS has always been to try to slow down the progression of the disease. Now we can tell our patients that a significant number can actually improve by reversing their disability," said lead researcher Dr. Gavin Giovannoni. He is a neurology professor at Queen Mary University of London in England. The treatment is not without its downsides, however. Because of the potential for side effects, people who received ... Read more

Related support groups: Multiple Sclerosis, Chronic Spasticity, Spasticity, Lemtrada, Upper Limb Spasticity, Campath, Alemtuzumab, Spinal Spasticity, Lower Limb Spasticity

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