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Gene Therapy May Fight Brain Cancer's Return

Posted 27 Oct 2017 by Drugs.com

FRIDAY, Oct. 27, 2017 – A new form of gene therapy shows promise in battling recurrent brain cancer. The phase 1 clinical trial included 56 patients with recurrent high-grade glioma brain cancer. Three years after the gene therapy treatment, more than a quarter of the patients were still alive. Median survival for patients was 14.4 months, compared with eight months typically seen in patients. "Given the deadly nature of this disease, three-year survival is rarely reported in the recurrent setting. It is notable that the survival benefit was seen across a range of patients, and not just limited to patients with specific genetic mutations," said study author Dr. Clark Chen. Chen is head of the department of neurosurgery at the University of Minnesota Medical School. He made his comments in news release from the American Association for Cancer Research. The study was sponsored by therapy ... Read more

Related support groups: Fluorouracil, Efudex, Brain Tumor, Carac, Glioblastoma Multiforme, Pituitary Tumor, Diagnosis and Investigation, Acromegaly, Fluoroplex, Pituitary Adenoma, Malignant Glioma, Tolak, Anaplastic Oligodendroglioma, Anaplastic Astrocytoma, Fluorac, Efudex Occlusion Pack, Angioblastoma, Adrucil, Diclofenac/fluorouracil

Half Report Severe Side Effects From Breast Cancer Therapy

Posted 24 Jan 2017 by Drugs.com

TUESDAY, Jan. 24, 2017 – About half of early stage breast cancer patients experience severe side effects from their treatment, a new study finds. "It's in patients' best interest to receive their treatments on time and on schedule, whenever possible, to give them the best possible outcome," said study author Dr. Steven Katz. He's professor of health management and policy at the University of Michigan. "Unscheduled care for toxicities [side effects] – including clinic visits, emergency department visits and hospital stays – are expensive, inconvenient and disruptive to both doctors and patients. We need to avoid them whenever possible," Katz said in a university news release. For the study, researchers surveyed almost 2,000 early stage breast cancer patients an average of seven months after diagnosis. The women were asked to rate the severity of seven common treatment side effects: ... Read more

Related support groups: Surgery, Breast Cancer, Fluorouracil, Efudex, Breast Cancer, Metastatic, Carac, Herceptin, Taxol, Breast Cancer - Adjuvant, Taxotere, Breast Cancer, Prevention, Carboplatin, Cytoxan, Cyclophosphamide, Paclitaxel, Breast Cancer - Palliative, Fluoroplex, Doxorubicin, Adriamycin, Kadcyla

Skin Cancer Cream Linked to 5 Dog Deaths: FDA

Posted 20 Jan 2017 by Drugs.com

THURSDAY, Jan. 19, 2017 – Five dogs have died from exposure to a skin cancer cream prescribed for people, according to the U.S. Food and Drug Administration. Ingesting very small amounts of the drug – fluorouracil topical cream USP 5% (5-FU) – can sicken or kill family pets, said the FDA. "Although the FDA has not to date received any reports involving cats, they are also expected to be extremely sensitive to fluorouracil cream," the agency said in a news release. The drug is also marketed under the brand names Carac, Efudex and Fluoroplex, the FDA said. It's used to treat precancerous sun-damaged skin as well as some basal cell skin cancers, according to the American Cancer Society. In one case, a dog merely punctured the tube of fluorouracil in its mouth before its owner could grab it. The pooch died 12 hours later, after vomiting and suffering seizures. In another instance, a dog ... Read more

Related support groups: Fluorouracil, Efudex, Basal Cell Carcinoma, Carac, Skin Cancer, Melanoma, Melanoma - Metastatic, Fluoroplex, Tolak, History - Skin Cancer, Diclofenac/fluorouracil, Efudex Occlusion Pack, Fluorac, Adrucil

Retail Prices of Dermatology Drugs Skyrocket

Posted 25 Nov 2015 by Drugs.com

WEDNESDAY, Nov. 25, 2015 – Patients using prescription creams, gels, sprays and pills for skin conditions may shell out substantially more at the pharmacy than they did just six years ago, a new study suggests. Between 2009 and 2015, retail prices of brand-name dermatologic drugs rose 401 percent, on average, study authors reported Nov. 25 in JAMA Dermatology. Even generics have succumbed to price inflation, up 279 percent between 2011 and 2014, based on the drugs surveyed. Price increases for skin treatments far outpaced the general inflation rate of 11 percent during the six-year study period, the researchers said. "Cancer drugs were the worst in terms of the numbers" – up 1,240 percent or nearly $11,000 over the six-year study period – primarily because of two medicines, said Dr. Steven Rosenberg, voluntary professor of dermatology at the University of Miami Miller School of ... Read more

Related support groups: Monistat, RID, Monistat 3, Eczema, Monistat 7, Voltaren Gel, Dermatitis, Maintain, Clobetasol, Contact Dermatitis, Mupirocin, Epiduo, Sulfur, Drysol, Therapeutic, Efudex, Basal Cell Carcinoma, Bactroban, Silver, Retin-A

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