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Dutasteride News

Drug May Slow Early Prostate Cancer: Study

Posted 24 Jan 2012 by Drugs.com

TUESDAY, Jan. 24 – New research suggests that Avodart, a drug used to treat an enlarged prostate gland, may help slow the progression of early stage prostate cancer, reducing the need for aggressive treatment in some men. Prostate cancer can grow and spread slowly, which is why some men are urged to engage in so-called watchful waiting when the cancer is first diagnosed. Avodart (dutasteride) may help such men feel comfortable with surveillance as opposed to radical treatment, the researchers noted. "The concept of active surveillance is gaining traction in most parts of the world," said study author Dr. Neil E. Fleshner, head of the division of urology at the Princess Margaret Hospital in Toronto. Still, some men are uncomfortable with doing nothing in the face of a cancer diagnosis, he said. "By using this drug, we can improve the proportion of men who remain committed to the ... Read more

Related support groups: Benign Prostatic Hyperplasia (BPH), Prostate Cancer, Avodart, Dutasteride

Drugs for Enlarged Prostate May Raise Risk of Aggressive Cancer

Posted 9 Jun 2011 by Drugs.com

THURSDAY, June 9 – The U.S. Food and Drug Administration is calling for new warning labels on a class of drugs used primarily to treat enlarged prostates, because the medications may raise the risk of developing an aggressive form of prostate cancer. In a statement released Thursday, the agency said the drugs involved include popular medications sold under the brand names Proscar and Propecia (sold by Merck & Co.) and Avodart and Jalyn (sold by GlaxoSmithKline). According to the FDA, almost 5 million men were prescribed one of these medications between 2002 and 2009. Of these, nearly 3 million men were between the ages of 50 and 79. The agency is advising doctors not to start patients on these drugs until prostate cancer – which can mimic the symptoms of an enlarged prostate – and other urological conditions have been ruled out. According to the agency, this new warning is based on ... Read more

Related support groups: Avodart, Finasteride, Propecia, Jalyn, Proscar, Dutasteride, Dutasteride/tamsulosin

FDA Medwatch Alert: 5-alpha reductase inhibitors (5-ARIs): Label Change - Increased Risk of Prostate Cancer

Posted 9 Jun 2011 by Drugs.com

Drugs in the 5-ARI class include finasteride and dutasteride. These drugs are marketed under the brand-names Proscar, Propecia, Avodart, and Jalyn ISSUE: FDA notified healthcare professionals that the Warnings and Precautions section of the labels for the 5-alpha reductase inhibitor (5-ARI) class of drugs has been revised to include new safety information about the increased risk of being diagnosed with a more serious form of prostate cancer (high-grade prostate cancer). BACKGROUND: The new safety information is based on FDA’s review of two large, randomized controlled trials––the Prostate Cancer Prevention Trial (PCPT) and the Reduction by Dutasteride of Prostate Cancer Events (REDUCE) trial. Proscar, Avodart, and Jalyn are approved to improve symptoms of an enlarged prostate gland (benign prostatic hyperplasia or BPH). Proscar and Avodart are also approved to reduce the risk of urina ... Read more

Related support groups: Avodart, Finasteride, Propecia, Jalyn, Proscar, Dutasteride, Dutasteride/tamsulosin

Sexual Side Effects From Propecia, Avodart May Be Irreversible

Posted 10 Mar 2011 by Drugs.com

THURSDAY, March 10 – Drugs frequently prescribed to treat hair loss or an enlarged prostate may contribute to irreversible sexual dysfunction in men, new research finds. Use of dutasteride (Avodart) and finasteride (Proscar and Propecia) were linked to erectile dysfunction, depression and loss of libido in a review of existing studies. In a small percentage of cases, symptoms persisted even after the medication was stopped. For those men, "it's a life sentence," said lead researcher Abdulmaged M. Traish, a professor of biochemistry and urology at Boston University School of Medicine. "No sex. No desire. Potential depression," Traish added. Almost everyone who takes these drugs experiences some of these side effects, Traish said. "But, some experience it more drastically than others," he added. The drugs – prescribed to treat a common urological condition called benign prostatic ... Read more

Related support groups: Avodart, Finasteride, Propecia, Proscar, Dutasteride

Study Revives Debate on Prostate Drug

Posted 2 Apr 2010 by Drugs.com

WEDNESDAY, March 31 – A new study to determine whether a drug prescribed to fight the problems of an enlarged prostate gland can also reduce the risk of prostate cancer promises to prolong a debate that started with an earlier study of a similar drug. The renewed debate plays out in the April 1 issue of the New England Journal of Medicine, which carries not only a report saying that the drug dutasteride (Avodart) may reduce the risk for prostate cancer but also an editorial that counters the upbeat conclusions of the study point by point. The results of the four-year study of the effect of Avodart on prostate – financed by Glaxo, which markets the drug – seem to mirror those of a 19,000-participant study in 2003 of finasteride (Propecia), which found a 25 percent lower incidence of prostate cancer among men who took that drug than among those who took a placebo. But that study has ... Read more

Related support groups: Avodart, Finasteride, Propecia, Proscar, Dutasteride

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Further Information

Related Condition Support Groups

Benign Prostatic Hyperplasia (BPH)

Related Drug Support Groups

Avodart

Dutasteride Patient Information at Drugs.com