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Constipation News

Related terms: Difficulty passing stool, Irregularity of bowels

Big Rise in Hospitalized Kids With Opioid Side Effects

Posted 6 days ago by Drugs.com

MONDAY, Sept. 18, 2017 – There has been a large increase in the number of young hospital patients in the United States who suffer harmful side effects from opioid painkillers, a new study says. The findings show an urgent need for safer pain medications for young patients, the researchers said. The researchers reviewed federal government data on hospital stays by children from 1 month to 17 years old. The data revealed the rate of opioid-related problems among these young hospital patients rose by more than 50 percent over nine years. The overall rate of opioid-related side effects during the study period was almost 17 per 10,000 discharges, the study found. Rates were highest among white children. That finding suggests that race may be a factor in which children are prescribed opioids to treat pain, the researchers said. Opioid-related problems included: opioid withdrawal (3 percent), ... Read more

Related support groups: Oxycodone, Hydrocodone, Percocet, OxyContin, Vicodin, Norco, Constipation, Lortab, Roxicodone, Endocet, Acetaminophen/Hydrocodone, Percocet 10/325, Vicoprofen, Acetaminophen/Oxycodone, Hydromet, Roxicet, Constipation - Drug Induced, Tussionex Pennkinetic, Lorcet 10/650, Vicodin ES

Human Gut Germs Dictated by Diet

Posted 25 Aug 2017 by Drugs.com

THURSDAY, Aug. 25, 2017 – What you eat, or don't eat, affects the mix of germs in your digestive tract, new research indicates. Thousands of microbial species thrive in the human intestine, helping people digest fiber and make vitamins and other molecules. They also help strengthen the immune system and protect against potentially harmful bacteria, Stanford University School of Medicine researchers say. The rise in farming some 15,000 years ago dramatically changed the human diet, the researchers noted. And in just the last 100 years, people have become increasingly sedentary and less likely to consume fiber-rich whole grains, fruits and vegetables. Antibiotics, cesarean sections and other lifestyle changes have also helped shift the composition of microbes in the human gut, the study authors added. To see how "progress" may have affected microbial diversity, the researchers examined ... Read more

Related support groups: Diarrhea, Constipation, Dietary Supplementation, Gastrointestinal Disorders, Dietary Fiber Supplementation, Acute Abdomen

FDA Announces Recall of Some Liquid Pharmaceutical Products

Posted 16 Aug 2017 by Drugs.com

WEDNESDAY, Aug. 16, 2017 – The U.S. Food and Drug Administration has announced a recall of numerous liquid pharmaceutical products because of possible bacterial contamination that could cause severe infections in vulnerable patients. The drugs and dietary supplements, made by PharmaTech LLC in Davie, Fla., include liquid stool softeners, liquid vitamin D drops and liquid multivitamins marketed for infants and children, the agency said in a news release. Reports of the discovery of Burkholderia cepacia bacteria in both Diocto Liquid and Diocto Syrup prompted the voluntary recall by three companies that label PharmaTech products, the FDA said. The three companies are Rugby Laboratories, Major Pharmaceuticals and Leader Brands. "B. cepacia poses a serious threat to vulnerable patients, including infants and young children who still have developing immune systems," FDA Commissioner Dr. ... Read more

Related support groups: Infections, Peri-DS, Constipation, Vitamin D, MiraLax, Magnesium Citrate, Dulcolax, Niacin, Folic Acid, Suprep, Vitamin D Deficiency, Lactulose, Deplin, Vitamin/Mineral Supplementation and Deficiency, Niaspan, Vitamin B12, Polyethylene Glycol 3350, Milk of Magnesia, Vitamin C, Metamucil

FDA Medwatch Alert: Liquid Drug Products Manufactured by PharmaTech and Distributed by Rugby Laboratories and Possibly Other Companies: FDA Advisory - Not to Use

Posted 8 Aug 2017 by Drugs.com

ISSUE: FDA is advising health care professionals and patients not to use any liquid product manufactured by PharmaTech LLC, Davie, Florida, due to Burkholderia cepacia contamination and the potential for severe patient infection. Rugby Laboratories, Livonia, Michigan, announced a voluntary recall on August 3, 2017, of two such products – Diocto Liquid and Diocto Syrup, both oral liquid docusate products – manufactured by PharmaTech. Additional liquid drug products manufactured by PharmaTech might also be affected. Such products might have been labeled and distributed by Rugby and other companies. Any company that purchased liquid products manufactured by PharmaTech should immediately quarantine material under their control and contact the local FDA pharmaceutical recall coordinator. Centers for Disease Control and Prevention laboratory testing of PharmaTech’s oral liquid docusate detec ... Read more

Related support groups: Constipation, Colace, Docusate, DOS, Dulcolax Stool Softener, Doc-Q-Lace, Ex-Lax Stool Softener, DocuSol Kids, Enemeez Mini, Surfak, DocuSol, Docu, Diocto, Surfak Stool Softener, Dioctosoftez, Genasoft, Docusoft S, Silace, Dioeze, Kaopectate Stool Softener

FDA Medwatch Alert: Diocto Liquid and Diocto Syrup by Rugby Laboratories: Recall - Possible Product Contamination

Posted 6 Aug 2017 by Drugs.com

[Posted 08/03/2017] ISSUE: Rugby Laboratories is voluntarily recalling all lots of Diocto Liquid and Diocto Syrup, (docusate sodium solutions) manufactured by PharmaTech, LLC due to a risk of product contamination with Burkholderia cepacia. FDA informed Rugby that it received several adverse event reports of B. cepacia infections in patients which may be linked to Diocto Liquid or Diocto Syrup manufactured by PharmaTech LLC. If a product contains B. cepacia, its use could result in infections in patients with compromised immune systems and in patients with chronic lung conditions such as cystic fibrosis. Some of these infections may be serious or even life-threatening in the at-risk patient population. All lots with NDC 0536-0590-85 and NDC 0536-1001-85 are included in this recall. BACKGROUND: Diocto Liquid and Diocto Syrup are used as stool softeners and are packaged in one pint (473 ... Read more

Related support groups: Constipation, Diocto

Health Tip: Help Manage Constipation

Posted 20 Apr 2017 by Drugs.com

-- Many lifestyle factors – such as diet, exercise and fluid intake – are associated with constipation. To help tame the problem, the Cleveland Clinic recommends: Drink two-to-four cups of water daily. Also drink warm liquids, particularly in the morning. Eat plenty of fruit (such as prunes) and vegetables. Eat bran cereals. Take a fiber supplement. Get regular exercise. Use a mild stool softener or laxative, but don't take it for longer than necessary (two weeks maximum). See your doctor if symptoms don't improve within three weeks. Read more

Related support groups: Peri-DS, Constipation, MiraLax, Magnesium Citrate, Constipation - Chronic, Dulcolax, Suprep, Lactulose, Polyethylene Glycol 3350, Milk of Magnesia, Metamucil, Fleet Enema, Bisacodyl, MoviPrep, Epsom Salt, Constipation - Acute, Senokot, Senna, Colace, Constipation - Drug Induced

FDA Approves Symproic (naldemedine) for the Treatment of Opioid-Induced Constipation

Posted 24 Mar 2017 by Drugs.com

OSAKA, Japan and FLORHAM PARK, N.J. and STAMFORD, Conn., March 23, 2017 /PRNewswire/ – Shionogi Inc. and Purdue Pharma L.P. announced today that the U.S. Food and Drug Administration (FDA) approved Symproic® (naldemedine) 0.2 mg tablets C-II as a once-daily oral peripherally-acting mu-opioid receptor antagonist (PAMORA) medication for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain. Symproic is currently a Schedule II controlled substance because it is structurally related to naltrexone. Shionogi Inc. submitted a petition for the descheduling of Symproic, or removal of the controlled substance classification, to the U.S. Drug Enforcement Administration (DEA), which is currently under evaluation. Symproic will be jointly launched and commercialized in the U.S. with Purdue Pharma and is expected to be commercially available mid-summer. ... Read more

Related support groups: Oxycodone, Hydrocodone, Fentanyl, Constipation, Morphine, Hydromorphone, Acetaminophen/Hydrocodone, Acetaminophen/Oxycodone, Constipation - Drug Induced, Symproic, Narcotic Analgesics, Narcotic Analgesic Combinations, Naldemedine

Health Tip: Watch for Constipation in Babies

Posted 9 Mar 2017 by Drugs.com

-- A crying, fussing baby has few ways to express what's wrong. But parents piece together clues that point to constipation. The American Academy of Pediatrics says warning signs of constipation in infants include: Excessive fussiness. Spitting up frequently. Significantly fewer bowel movements. Passing hard or bloody stools. Straining to pass a bowel movement for more than 10 minutes. Read more

Related support groups: Constipation, Constipation - Chronic, Delivery, Constipation - Acute, Labor and Delivery including Augmentation, Fecal Impaction

U.S. FDA Approves 72 mcg Dose of Linzess (linaclotide) for Adults with Chronic Idiopathic Constipation

Posted 30 Jan 2017 by Drugs.com

CAMBRIDGE, Mass. and DUBLIN, Jan. 26, 2017 /PRNewswire/ – Ironwood Pharmaceuticals, Inc. (NASDAQ: IRWD) and Allergan plc (NYSE: AGN) announced today that the U.S. Food and Drug Administration (FDA) has approved a 72 mcg dose of Linzess (linaclotide) for the treatment of chronic idiopathic constipation (CIC) in adult patients. The newly approved dose will provide physicians with dosing flexibility based on individual presentation or tolerability, in treating the large and heterogenous population of adult CIC patients. The new dose is expected to be available in the first quarter of 2017. Linzess is now FDA-approved in three dosage strengths: 290 mcg for adult patients with irritable bowel syndrome with constipation (IBS-C), and 145 mcg and a new 72 mcg for the treatment of adults with CIC. Since the launch of Linzess in December of 2012, nearly 1.5 million unique patients have filled ... Read more

Related support groups: Constipation, Linzess, Constipation - Chronic, Linaclotide

Fecal Transplant Shows Early Promise Against Autism

Posted 27 Jan 2017 by Drugs.com

THURSDAY, Jan. 26, 2017 – A small study suggests a novel treatment for kids with autism: Give these young patients a fresh supply of healthy gut bacteria via a fecal transplant. After the procedure, the children experienced a 25 percent reduction in symptoms related to language, social interaction and repetitive behaviors, said study co-author James Adams, an autism researcher at Arizona State University. Not only that, the kids also became less hyperactive, irritable and lethargic, Adams said. "It's not a cure for autism, but in 10 weeks we were able to make a substantial dent," he said. Many children with autism suffer from chronic gastrointestinal problems like diarrhea and constipation, often from infancy, Adams explained. That may be because they either carry harmful gut bacteria or lack many healthy strains. "Most people have about a thousand different species of bacteria in ... Read more

Related support groups: Diarrhea, Constipation, Autism, Gastrointestinal Disorders, Acidophilus, Diarrhea, Chronic, Asperger Syndrome, Florastor, Diarrhea, Acute, VSL#3, Lactobacillus Acidophilus, Lactinex, Flora-Q, Floranex, Saccharomyces Boulardii Lyo, Flora-Q 2, Bio-K+, Florajen, Restora, Probiotic Formula

FDA Approves Trulance (plecanatide) for Chronic Idiopathic Constipation

Posted 25 Jan 2017 by Drugs.com

January 19, 2017 – The U.S. Food and Drug Administration today approved Trulance (plecanatide) for the treatment of Chronic Idiopathic Constipation (CIC) in adult patients. “No one medication works for all patients suffering from chronic gastrointestinal disorders,” said Julie Beitz, M.D., director of the Office of Drug Evaluation III in the FDA’s Center for Drug Evaluation and Research. “With the availability of new therapies, patients and their doctors can select the most appropriate treatment for their condition.” According to the National Institutes of Health, an estimated 42 million people are affected by constipation. Chronic idiopathic constipation is a diagnosis given to those who experience persistent constipation and for whom there is no structural or biochemical explanation. Trulance, taken orally once daily, works locally in the upper GI tract to stimulate secretion of int ... Read more

Related support groups: Constipation, Constipation - Chronic, Trulance, Plecanatide

Trulance Approved for Chronic Constipation

Posted 22 Jan 2017 by Drugs.com

FRIDAY, Jan. 20, 2017 – Trulance (plecanatide) has been approved by the U.S. Food and Drug Administration to treat persistent constipation of unknown (idiopathic) cause in adults. Some 42 million people in the United States are affected by constipation, according to the National Institutes of Health. Once-daily Trulance is designed to stimulate the upper gastrointestinal tract to secrete fluid and "support regular bowel function," the FDA said in a news release. The oral drug was evaluated in two 12-week clinical studies involving a total of 1,775 adults with chronic constipation. Diarrhea was the most common side effect. If diarrhea becomes severe, users should stop taking Trulance and contact a doctor, the FDA advised. Trulance is produced by New York City-based Synergy Pharmaceuticals. More information Visit the FDA to learn more about this approval. Read more

Related support groups: Diarrhea, Constipation, Constipation - Chronic, Constipation - Drug Induced, Diarrhea, Acute, Trulance, Fecal Impaction, Plecanatide

Health Tip: Concerned About Constipation?

Posted 12 Jan 2017 by Drugs.com

-- Constipation occurs when bowel movements happen infrequently or are difficult to pass. Sometimes, lifestyle changes can curb constipation, but other times the condition signals something more serious. The Cleveland Clinic says to see a doctor if: It isn't "normal" for you to be constipated. You notice any blood in your stools. You lose weight without trying. It becomes very painful to pass a bowel movement. You are constipated for an extended period. Read more

Related support groups: Constipation, Colonoscopy, Constipation - Chronic, Colorectal Cancer, Constipation - Acute

Constipation, Kidney Disease May Be Linked, New Research Shows

Posted 11 Nov 2016 by Drugs.com

THURSDAY, Nov. 10, 2016 – People with constipation are more likely to develop kidney disease, a new study finds. The discovery suggests kidney problems might be prevented or treated by managing constipation, according to researchers at the University of Tennessee Health Science Center and Memphis VA Medical Center. They studied the medical records of 3.5 million U.S. veterans with normal kidney function. They were tracked from 2004 to 2006, and followed through 2013. Those with constipation were 13 percent more likely than patients without constipation to develop chronic kidney disease and 9 percent more likely to experience kidney failure. The risk was even higher for those whose constipation was more severe. The study did not prove that constipation causes kidney disease or failure, however. Instead, "Our findings highlight the plausible link between the gut and the kidneys and ... Read more

Related support groups: Constipation, Renal Failure, Constipation - Chronic, Chronic Kidney Disease, Constipation - Acute, Constipation - Drug Induced, Fecal Impaction, Renal and Genitourinary Disorders

The Scoop About Healthy Poop

Posted 25 Oct 2016 by Drugs.com

TUESDAY, Oct. 25, 2016 – Your bowel movements can offer important clues about your health, a doctor says. If bowel movements feel comfortable, then it's likely all is well, said Dr. Gabriel Neal, a family medicine doctor and clinical assistant professor at Texas A&M College of Medicine. "Normal bowel movements are relatively soft but dense. They should be any shade of brown or green," Neal said in a college news release. Viruses and bacteria in the intestinal tract can cause stool discoloration, diarrhea or blood in the stool. The color of the blood can help your doctor pinpoint the location of the infection. "If an infection is in the lower intestines or colon, then the blood in your stool is going to be red. If you find black blood, then the blood has oxidized and is from higher up in your digestive tract, such as the stomach or upper intestines," Neal said. People with gallbladder ... Read more

Related support groups: Diarrhea, Constipation, Crohn's Disease, Constipation - Chronic, Gastrointestinal Disorders, Gallbladder Disease, Inflammatory Bowel Disease, Constipation - Acute, Diarrhea, Chronic, Diarrhea, Acute, Infectious Diarrhea

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Constipation - Chronic, Constipation - Acute, Constipation - Drug Induced, Opioid-Induced Constipation, Chronic Idiopathic Constipation, Fecal Impaction, Gastrointestinal Disorders

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