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Constipation News

Related terms: Difficulty passing stool, Irregularity of bowels

Valeant and Progenics Announce FDA Approves Relistor Tablets for the Treatment of Opioid-Induced Constipation in Adults with Chronic Non-Cancer Pain

Posted 1 day 8 hours ago by Drugs.com

LAVAL, Quebec and TARRYTOWN, N.Y., July 19, 2016 /PRNewswire/ – Valeant Pharmaceuticals International, Inc. (NYSE & TSX: VRX) and Progenics Pharmaceuticals, Inc. (Nasdaq: PGNX) today announced that the U.S. Food and Drug Administration has approved Relistor (methylnaltrexone bromide) Tablets for the treatment of opioid-induced constipation (OIC) in adults with chronic non-cancer pain. Valeant expects to commence sales of Relistor Tablets in the U.S. in the third quarter of 2016. "Opioid-induced constipation represents a long-lasting and potentially debilitating side effect of opioid therapy for millions of patients suffering from chronic pain," commented Joseph C. Papa, Chief Executive Officer of Valeant. "We believe Oral Relistor represents a new alternative treatment for OIC, and we look forward to introducing the more convenient oral formulation as soon as practicable." "We are ... Read more

Related support groups: Constipation, Constipation - Drug Induced, Relistor, Methylnaltrexone

FDA Medwatch Alert: Oral Liquid Docusate Sodium by PharmaTech : Recall - Contaminated with B. cepacia

Posted 10 days ago by Drugs.com

ISSUE: The FDA is alerting health care professionals that PharmaTech LLC, Davie, Florida, is voluntarily recalling all non-expired lots of Diocto Liquid, a docusate sodium solution distributed by Rugby Laboratories, Livonia, Michigan. The agency confirmed the product has been contaminated with Burkholderia cepacia, a bacteria linked to an outbreak in five states. In addition, FDA has received several adverse event reports of B. cepacia infections in patients. Some of these reports identify liquid docusate sodium products manufactured by companies other than PharmaTech. FDA and the Centers for Disease Control and Prevention continue to investigate the extent of this issue in order to identify other potentially contaminated liquid docusate sodium products. BACKGROUND: PharmaTech manufactures the oral liquid docusate sodium, which is distributed nationwide by Rugby with a Rugby label in ... Read more

Related support groups: Constipation, Colace, Docusate, DOS, Doc-Q-Lace, Ex-Lax Stool Softener, Surfak Stool Softener, Diocto, Enemeez Mini, Surfak, Octycine-100, Docu, Phillips Stool Softener, Promolaxin, Calcium Stool Softener, Docucal, Genasoft, Dioctosoftez, Docusoft S, Silace

Health Tip: Laxatives Have Side Effects

Posted 8 Jun 2016 by Drugs.com

-- Laxatives can have unpleasant side effects, especially when overused. The American Academy of Family Physicians says possible problems associated with laxative use include: Abdominal cramps or nausea. Gas, diarrhea or bloating. Electrolyte imbalance, which can affect the muscles, nerves and organs. Those most at risk include children and people with kidney disease or diabetes. Muscle weakness or muscle spasms. Fatigue, confusion, headache or vomiting. Read more

Related support groups: Peri-DS, Constipation, MiraLax, Dulcolax, Magnesium Citrate, Constipation - Chronic, Lactulose, Suprep, Polyethylene Glycol 3350, Metamucil, Milk of Magnesia, Epsom Salt, Bisacodyl, Fleet Enema, MoviPrep, Senna, Colace, Constipation - Acute, Senokot, Constipation - Drug Induced

DNA May Affect What Bugs Reside in Your Gut

Posted 11 May 2016 by Drugs.com

WEDNESDAY, May 11, 2016 – At least some of the microbes that live in your gut may be influenced by your genes, a new study finds. "We set out to find out about human genes that are implicated in the regulation of the gut microbiome, and we found some that are," said senior study author Ruth Ley, an associate professor in the department of microbiology at Cornell University, in Ithaca, N.Y. For example, the researchers found a link between the LCT gene – involved in making the enzyme that helps the body digest dairy products – and a type of microorganism called Bifidobacterium, which is commonly used in probiotics. "Based on our research, we identified more than a dozen microbes with known links to health that are heritable," Ley said. "These microorganisms are environmentally acquired, but the genome also plays a part – by determining which microorganisms are more dominant than ... Read more

Related support groups: Diarrhea, Constipation, Gas, Gastrointestinal Disorders, Duodenitis/Gastritis, Florajen3, Probiotic Formula, VSL#3, ReZyst IM, Bifidobacterium Infantis, Healthy Colon, Align, VSL#3 DS, Provella, Gastric Motility Disorder, VLS#3, Bifidobacterium Infantis/lactobacillus Acidophilus

Stomach Troubles Not Linked to Autism, Study Finds

Posted 15 Mar 2016 by Drugs.com

MONDAY, March 14, 2016 – Children with autism are not at higher risk for certain digestive system problems than those without the neurodevelopmental disorder, a small study suggests. The researchers focused on gastrointestinal disorders that previous studies suggested might be linked to autism. These include intestinal inflammation; deficiency of the digestive enzyme lactase, associated with lactose intolerance; and increased intestinal permeability, often called "leaky gut." The results showed that the children with autism were no more likely to have these conditions than typically developing kids. The research was published recently in the Journal of Pediatric Gastroenterology and Nutrition. "The results of this study suggest that common gastrointestinal problems occur in children with autism and should be evaluated," Dr. Timothy Buie, MassGeneral Hospital for Children, Boston, and ... Read more

Related support groups: Diarrhea, Constipation, Autism, Gastrointestinal Disorders, Asperger Syndrome, Acute Abdomen

Health Tip: Your Child's Bowel Function

Posted 25 Aug 2015 by Drugs.com

-- Every child has different bowel habits, but certain signs may indicate a medical problem. The University of Michigan Health System says parents should visit a doctor if: The child is constipated for longer than a week, or the child's bowel movements are painful and require more than normal pushing. The child has blood in the stool, or has hemorrhoids. The child has a leaking soft stool between bowel movements. The child is vomiting or has a swollen belly. Read more

Related support groups: Constipation, Constipation - Chronic, Hemorrhoids, Constipation - Acute, Infectious Gastroenteritis, Traveler's Diarrhea

Health Tip: Should I Talk to my Doctor About Gas?

Posted 10 Aug 2015 by Drugs.com

-- While everyone has intestinal gas, some people have severe bloating that causes discomfort and other problems. The Mayo Clinic mentions these warning signs that you may need to see a doctor: Intestinal gas that is persistent and severe. Intestinal gas that occurs with vomiting. Long-term diarrhea, bloody stool or constipation. Weight loss for no apparent reason. Heartburn. Read more

Related support groups: GERD, Diarrhea, Constipation, Gas, Abdominal Distension, Weight Loss, Colitis, Indigestion, Constipation - Chronic, Gastrointestinal Disorders, Hemorrhoids, Inflammatory Bowel Disease, Constipation - Acute, Duodenitis/Gastritis, Diarrhea, Chronic, Anal Fissure and Fistula, Diarrhea, Acute, Infectious Diarrhea, Functional Gastric Disorder, Acute Abdomen

Autism Tied to Higher Risk for Gut Troubles in Children

Posted 25 Mar 2015 by Drugs.com

WEDNESDAY, March 25, 2015 – Children with autism tend to have more gastrointestinal problems early in life compared to other children, a new study finds. Researchers compared these GI symptoms – such as diarrhea, constipation and food allergy/intolerance – during the first three years of life among three groups of Norwegian children. One group included 195 children with autism, another included more than 4,600 children with developmental delays, and the third group included more than 40,000 children who developed typically. Compared to those with typical development, children with autism were more likely to have constipation and diarrhea when they were ages 6 months to 18 months, and more likely to have diarrhea, constipation and food allergy/intolerance when they were ages 18 months to 36 months, the researchers said. Children with an autism spectrum disorder (ASD) were more likely ... Read more

Related support groups: Allergic Reactions, Diarrhea, Allergies, Constipation, Autism

Health Tip: Risk Factors for Constipation

Posted 20 Jan 2015 by Drugs.com

-- Constipation is characterized by difficulty or infrequently passing bowel movements. The American Academy of Family Physicians mentions these risk factors: Getting less than 20 grams to 35 grams of dietary fiber each day. Getting insufficient fluids, which allows stools to dry out. Getting insufficient exercise. Avoiding passing bowel movements when you feel the urge. Taking certain medications, such as opiates. Undergoing changes in your life or routine, including travel or pregnancy. Having certain diseases or conditions, such as diabetes, lupus or multiple sclerosis. Having an intestinal problem, such as an obstruction, irritable bowel syndrome or a tumor. Read more

Related support groups: Constipation

FDA Approves Movantik (naloxegol) for Opioid-Induced Constipation

Posted 16 Sep 2014 by Drugs.com

September 16, 2014 – The U.S. Food and Drug Administration today approved Movantik (naloxegol), an oral treatment for opioid-induced constipation in adults with chronic non-cancer pain. Opioids are a class of drugs that are used to treat and manage pain. A common side effect associated with the use of these drugs are that they reduce the gastrointestinal tract’s motility, making bowel movements difficult and causing patients to strain, have hard or lumpy stools or experience a sensation of incomplete evacuation. Movantik belongs to a class of drugs called peripherally acting opioid receptor antagonists, which are used to decrease the constipating effects of opioids. “Supportive care products such as Movantik can lessen the constipating side effects of opioids,” said Julie Beitz, M.D., director of the Office of Drug Evaluation III in the FDA’s Center for Drug Evaluation and Research. ... Read more

Related support groups: Constipation

Doctors Often Suggest Pricier, Brand-Name Meds for Reflux: Study

Posted 6 May 2014 by Drugs.com

SATURDAY, May 3, 2014 – Doctors often recommend brand-name drugs for acid reflux and chronic constipation instead of cheaper store brands, costing patients more money, a new study finds. The survey included more than 800 gastroenterologists across the United States who were asked about their drug recommendations for patients with the two digestive conditions. The study was funded by generic drug maker Perrigo. The study found that 63 percent of the doctors would recommend an over-the-counter (OTC) drug, rather than a prescription medicine, to treat acid reflux. However, while three-quarters of the doctors felt that OTC brand-name and store-brand proton pump inhibitor drugs were equally effective, 54 percent of them recommended brand-name drugs to patients at least one-third of the time. For chronic constipation, 95 percent of the gastroenterologists said they would suggest OTC ... Read more

Related support groups: GERD, Constipation

Health Tip: If Your Child is Constipated

Posted 18 Apr 2014 by Drugs.com

-- Constipation among children often isn't worth worrying about, and resolves on its own. But you shouldn't ignore signs that the problem may be serious, and that your child should be examined by a doctor. The University of Michigan Health System says these symptoms should be evaluated by a pediatrician: If constipation persists longer than one week. If there is blood in the child's stool. If the child develops hemorrhoids. If a bowel movement becomes very painful. If the child leaks soft stools or liquid between bowel movements. If constipation is accompanied by vomiting. If the child's belly is swollen. Read more

Related support groups: Constipation

FDA Medwatch Alert: Sodium Phosphate Over-the-Counter Products: Drug Safety Communication - Possible Harm From Exceeding Recommended Dose

Posted 8 Jan 2014 by Drugs.com

Marketed under the brand-name Fleet, and as store brands and generic products.   [Posted 01/08/2014] ISSUE: FDA is warning that using more than one dose in 24 hours of over-the-counter (OTC) sodium phosphate drugs to treat constipation can cause rare but serious harm to the kidneys and heart, and even death.  FDA has become aware of reports of severe dehydration and changes in the levels of serum electrolytes from taking more than the recommended dose of OTC sodium phosphate products, resulting in serious adverse effects on organs, such as the kidneys and heart, and in some cases resulting in death. These serum electrolytes include calcium, sodium, and phosphate. According to the reports, most cases of serious harm occurred with a single dose of sodium phosphate that was larger than recommended or with more than one dose in a day. For additional clinical information, see the FDA Drug S ... Read more

Related support groups: Constipation, Sodium Phosphate

Bowel Issues Affect 3 Out of 4 Pregnant Women

Posted 24 May 2013 by Drugs.com

FRIDAY, May 24 – Nearly three out of four pregnant women experience bowel problems such as constipation and diarrhea, but these issues don't significantly affect their quality of life, a new study finds. Researchers from Loyola University Medical Center in Maywood, Ill., noted that these bowel issues are due to physiological and hormonal changes that occur during pregnancy. Nutritional supplements that women take during pregnancy also can play a role. The study authors added that since women expect these problems to arise during pregnancy, they're better able to tolerate them. The study included 104 women in their first trimester of pregnancy and 66 women in their third trimester. They completed two questionnaires: one asking about the bowel disorders they experienced and another on how these problems affected their quality of life. Specifically, the women were asked if their bowel ... Read more

Related support groups: Diarrhea, Constipation

FDA Approves Amitiza for Opioid-Induced Constipation

Posted 23 Apr 2013 by Drugs.com

BETHESDA, Md. & DEERFIELD, Ill.--(BUSINESS WIRE)--Apr. 23, 2013-- Sucampo Pharmaceuticals, Inc. and Takeda Pharmaceuticals U.S.A., Inc. announced today that the United States (U.S.) Food and Drug Administration (FDA) has approved Sucampo’s supplemental new drug application (sNDA) for Amitiza (lubiprostone) (24 mcg twice daily) as the first and only oral medication for the treatment of opioid-induced constipation (OIC) in adult patients with chronic, non-cancer pain. The effectiveness of Amitiza in the treatment of opioid-induced constipation in patients taking diphenylheptane opioids (e.g., methadone) has not been established. This is the third indication for Amitiza, which is also approved in the U.S. for the treatment of chronic idiopathic constipation (CIC) in adults (24 mcg twice daily) and irritable bowel syndrome with constipation (IBS-C) in adult women (8 mcg twice daily). There ... Read more

Related support groups: Constipation, Amitiza, Constipation - Drug Induced, Lubiprostone

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Constipation - Chronic, Constipation - Acute, Constipation - Drug Induced, Gastrointestinal Disorders

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