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Constipation News

Related terms: Difficulty passing stool, Irregularity of bowels

Health Tip: Help Manage Constipation

Posted 5 days ago by Drugs.com

-- Many lifestyle factors – such as diet, exercise and fluid intake – are associated with constipation. To help tame the problem, the Cleveland Clinic recommends: Drink two-to-four cups of water daily. Also drink warm liquids, particularly in the morning. Eat plenty of fruit (such as prunes) and vegetables. Eat bran cereals. Take a fiber supplement. Get regular exercise. Use a mild stool softener or laxative, but don't take it for longer than necessary (two weeks maximum). See your doctor if symptoms don't improve within three weeks. Read more

Related support groups: Peri-DS, Constipation, MiraLax, Magnesium Citrate, Dulcolax, Constipation - Chronic, Suprep, Lactulose, Polyethylene Glycol 3350, Metamucil, Milk of Magnesia, Fleet Enema, Bisacodyl, MoviPrep, Epsom Salt, Constipation - Acute, Senokot, Senna, Colace, Docusate

FDA Approves Symproic (naldemedine) for the Treatment of Opioid-Induced Constipation

Posted 24 Mar 2017 by Drugs.com

OSAKA, Japan and FLORHAM PARK, N.J. and STAMFORD, Conn., March 23, 2017 /PRNewswire/ – Shionogi Inc. and Purdue Pharma L.P. announced today that the U.S. Food and Drug Administration (FDA) approved Symproic® (naldemedine) 0.2 mg tablets C-II as a once-daily oral peripherally-acting mu-opioid receptor antagonist (PAMORA) medication for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain. Symproic is currently a Schedule II controlled substance because it is structurally related to naltrexone. Shionogi Inc. submitted a petition for the descheduling of Symproic, or removal of the controlled substance classification, to the U.S. Drug Enforcement Administration (DEA), which is currently under evaluation. Symproic will be jointly launched and commercialized in the U.S. with Purdue Pharma and is expected to be commercially available mid-summer. ... Read more

Related support groups: Oxycodone, Hydrocodone, Fentanyl, Morphine, Constipation, Hydromorphone, Acetaminophen/Hydrocodone, Acetaminophen/Oxycodone, Constipation - Drug Induced, Narcotic Analgesics, Symproic, Narcotic Analgesic Combinations, Naldemedine

Health Tip: Watch for Constipation in Babies

Posted 9 Mar 2017 by Drugs.com

-- A crying, fussing baby has few ways to express what's wrong. But parents piece together clues that point to constipation. The American Academy of Pediatrics says warning signs of constipation in infants include: Excessive fussiness. Spitting up frequently. Significantly fewer bowel movements. Passing hard or bloody stools. Straining to pass a bowel movement for more than 10 minutes. Read more

Related support groups: Constipation, Constipation - Chronic, Delivery, Constipation - Acute, Labor and Delivery including Augmentation, Fecal Impaction

U.S. FDA Approves 72 mcg Dose of Linzess (linaclotide) for Adults with Chronic Idiopathic Constipation

Posted 30 Jan 2017 by Drugs.com

CAMBRIDGE, Mass. and DUBLIN, Jan. 26, 2017 /PRNewswire/ – Ironwood Pharmaceuticals, Inc. (NASDAQ: IRWD) and Allergan plc (NYSE: AGN) announced today that the U.S. Food and Drug Administration (FDA) has approved a 72 mcg dose of Linzess (linaclotide) for the treatment of chronic idiopathic constipation (CIC) in adult patients. The newly approved dose will provide physicians with dosing flexibility based on individual presentation or tolerability, in treating the large and heterogenous population of adult CIC patients. The new dose is expected to be available in the first quarter of 2017. Linzess is now FDA-approved in three dosage strengths: 290 mcg for adult patients with irritable bowel syndrome with constipation (IBS-C), and 145 mcg and a new 72 mcg for the treatment of adults with CIC. Since the launch of Linzess in December of 2012, nearly 1.5 million unique patients have filled ... Read more

Related support groups: Constipation, Linzess, Constipation - Chronic, Linaclotide

Fecal Transplant Shows Early Promise Against Autism

Posted 27 Jan 2017 by Drugs.com

THURSDAY, Jan. 26, 2017 – A small study suggests a novel treatment for kids with autism: Give these young patients a fresh supply of healthy gut bacteria via a fecal transplant. After the procedure, the children experienced a 25 percent reduction in symptoms related to language, social interaction and repetitive behaviors, said study co-author James Adams, an autism researcher at Arizona State University. Not only that, the kids also became less hyperactive, irritable and lethargic, Adams said. "It's not a cure for autism, but in 10 weeks we were able to make a substantial dent," he said. Many children with autism suffer from chronic gastrointestinal problems like diarrhea and constipation, often from infancy, Adams explained. That may be because they either carry harmful gut bacteria or lack many healthy strains. "Most people have about a thousand different species of bacteria in ... Read more

Related support groups: Diarrhea, Constipation, Autism, Gastrointestinal Disorders, Acidophilus, Diarrhea, Chronic, Asperger Syndrome, Florastor, Diarrhea, Acute, VSL#3, Lactobacillus Acidophilus, Lactinex, Flora-Q, Floranex, BD Lactinex, Florajen3, Flora-Q 2, Bio-K+, Florajen, Restora

FDA Approves Trulance (plecanatide) for Chronic Idiopathic Constipation

Posted 25 Jan 2017 by Drugs.com

January 19, 2017 – The U.S. Food and Drug Administration today approved Trulance (plecanatide) for the treatment of Chronic Idiopathic Constipation (CIC) in adult patients. “No one medication works for all patients suffering from chronic gastrointestinal disorders,” said Julie Beitz, M.D., director of the Office of Drug Evaluation III in the FDA’s Center for Drug Evaluation and Research. “With the availability of new therapies, patients and their doctors can select the most appropriate treatment for their condition.” According to the National Institutes of Health, an estimated 42 million people are affected by constipation. Chronic idiopathic constipation is a diagnosis given to those who experience persistent constipation and for whom there is no structural or biochemical explanation. Trulance, taken orally once daily, works locally in the upper GI tract to stimulate secretion of int ... Read more

Related support groups: Constipation, Constipation - Chronic, Trulance, Plecanatide

Trulance Approved for Chronic Constipation

Posted 22 Jan 2017 by Drugs.com

FRIDAY, Jan. 20, 2017 – Trulance (plecanatide) has been approved by the U.S. Food and Drug Administration to treat persistent constipation of unknown (idiopathic) cause in adults. Some 42 million people in the United States are affected by constipation, according to the National Institutes of Health. Once-daily Trulance is designed to stimulate the upper gastrointestinal tract to secrete fluid and "support regular bowel function," the FDA said in a news release. The oral drug was evaluated in two 12-week clinical studies involving a total of 1,775 adults with chronic constipation. Diarrhea was the most common side effect. If diarrhea becomes severe, users should stop taking Trulance and contact a doctor, the FDA advised. Trulance is produced by New York City-based Synergy Pharmaceuticals. More information Visit the FDA to learn more about this approval. Read more

Related support groups: Diarrhea, Constipation, Constipation - Chronic, Constipation - Drug Induced, Diarrhea, Acute, Trulance, Fecal Impaction, Plecanatide

Health Tip: Concerned About Constipation?

Posted 12 Jan 2017 by Drugs.com

-- Constipation occurs when bowel movements happen infrequently or are difficult to pass. Sometimes, lifestyle changes can curb constipation, but other times the condition signals something more serious. The Cleveland Clinic says to see a doctor if: It isn't "normal" for you to be constipated. You notice any blood in your stools. You lose weight without trying. It becomes very painful to pass a bowel movement. You are constipated for an extended period. Read more

Related support groups: Constipation, Colonoscopy, Constipation - Chronic, Colorectal Cancer, Constipation - Acute

Constipation, Kidney Disease May Be Linked, New Research Shows

Posted 11 Nov 2016 by Drugs.com

THURSDAY, Nov. 10, 2016 – People with constipation are more likely to develop kidney disease, a new study finds. The discovery suggests kidney problems might be prevented or treated by managing constipation, according to researchers at the University of Tennessee Health Science Center and Memphis VA Medical Center. They studied the medical records of 3.5 million U.S. veterans with normal kidney function. They were tracked from 2004 to 2006, and followed through 2013. Those with constipation were 13 percent more likely than patients without constipation to develop chronic kidney disease and 9 percent more likely to experience kidney failure. The risk was even higher for those whose constipation was more severe. The study did not prove that constipation causes kidney disease or failure, however. Instead, "Our findings highlight the plausible link between the gut and the kidneys and ... Read more

Related support groups: Constipation, Renal Failure, Constipation - Chronic, Chronic Kidney Disease, Constipation - Acute, Constipation - Drug Induced, Renal and Genitourinary Disorders, Fecal Impaction

The Scoop About Healthy Poop

Posted 25 Oct 2016 by Drugs.com

TUESDAY, Oct. 25, 2016 – Your bowel movements can offer important clues about your health, a doctor says. If bowel movements feel comfortable, then it's likely all is well, said Dr. Gabriel Neal, a family medicine doctor and clinical assistant professor at Texas A&M College of Medicine. "Normal bowel movements are relatively soft but dense. They should be any shade of brown or green," Neal said in a college news release. Viruses and bacteria in the intestinal tract can cause stool discoloration, diarrhea or blood in the stool. The color of the blood can help your doctor pinpoint the location of the infection. "If an infection is in the lower intestines or colon, then the blood in your stool is going to be red. If you find black blood, then the blood has oxidized and is from higher up in your digestive tract, such as the stomach or upper intestines," Neal said. People with gallbladder ... Read more

Related support groups: Diarrhea, Constipation, Crohn's Disease, Constipation - Chronic, Gastrointestinal Disorders, Inflammatory Bowel Disease, Gallbladder Disease, Constipation - Acute, Diarrhea, Chronic, Diarrhea, Acute, Infectious Diarrhea

Can Acupuncture Ease Severe Constipation?

Posted 12 Sep 2016 by Drugs.com

MONDAY, Sept. 12, 2016 – People with severe chronic constipation may get relief from a more modern type of acupuncture, new research suggests. After eight weeks of treatment with electroacupuncture – acupuncture involving electrical stimulation – study participants experienced significant symptom and quality-of-life improvements, the study found. Electroacupuncture uses thin needles inserted beneath the skin that are attached to a device that sends electric pulses into the body. The study findings suggest a safe and effective option for difficult-to-treat patients, several gastroenterologists said. "It is heartening to see such rigorously tested alternative therapies, since so many of them are administered without any evidence to support them," said Dr. Christopher Andrews. He's a clinical associate professor in the gastroenterology division at University of Calgary Cumming School of ... Read more

Related support groups: Constipation, Constipation - Chronic, Constipation - Acute, Constipation - Drug Induced

Valeant and Progenics Announce FDA Approves Relistor Tablets for the Treatment of Opioid-Induced Constipation in Adults with Chronic Non-Cancer Pain

Posted 28 Jul 2016 by Drugs.com

LAVAL, Quebec and TARRYTOWN, N.Y., July 19, 2016 /PRNewswire/ – Valeant Pharmaceuticals International, Inc. (NYSE & TSX: VRX) and Progenics Pharmaceuticals, Inc. (Nasdaq: PGNX) today announced that the U.S. Food and Drug Administration has approved Relistor (methylnaltrexone bromide) Tablets for the treatment of opioid-induced constipation (OIC) in adults with chronic non-cancer pain. Valeant expects to commence sales of Relistor Tablets in the U.S. in the third quarter of 2016. "Opioid-induced constipation represents a long-lasting and potentially debilitating side effect of opioid therapy for millions of patients suffering from chronic pain," commented Joseph C. Papa, Chief Executive Officer of Valeant. "We believe Oral Relistor represents a new alternative treatment for OIC, and we look forward to introducing the more convenient oral formulation as soon as practicable." "We are ... Read more

Related support groups: Constipation, Constipation - Drug Induced, Relistor, Methylnaltrexone

FDA Medwatch Alert: Oral Liquid Docusate Sodium by PharmaTech : Recall - Contaminated with B. cepacia

Posted 20 Jul 2016 by Drugs.com

ISSUE: The FDA is alerting health care professionals that PharmaTech LLC, Davie, Florida, is voluntarily recalling all non-expired lots of Diocto Liquid, a docusate sodium solution distributed by Rugby Laboratories, Livonia, Michigan. The agency confirmed the product has been contaminated with Burkholderia cepacia, a bacteria linked to an outbreak in five states. In addition, FDA has received several adverse event reports of B. cepacia infections in patients. Some of these reports identify liquid docusate sodium products manufactured by companies other than PharmaTech. FDA and the Centers for Disease Control and Prevention continue to investigate the extent of this issue in order to identify other potentially contaminated liquid docusate sodium products. BACKGROUND: PharmaTech manufactures the oral liquid docusate sodium, which is distributed nationwide by Rugby with a Rugby label in ... Read more

Related support groups: Constipation, Colace, Docusate, DOS, Doc-Q-Lace, Dulcolax Stool Softener, Ex-Lax Stool Softener, Enemeez Mini, Surfak, Diocto, Surfak Stool Softener, Calcium Stool Softener, Docucal, Phillips Stool Softener, Promolaxin, Dioctosoftez, Genasoft, Docusoft S, Silace, DocuSol Kids

Health Tip: Laxatives Have Side Effects

Posted 8 Jun 2016 by Drugs.com

-- Laxatives can have unpleasant side effects, especially when overused. The American Academy of Family Physicians says possible problems associated with laxative use include: Abdominal cramps or nausea. Gas, diarrhea or bloating. Electrolyte imbalance, which can affect the muscles, nerves and organs. Those most at risk include children and people with kidney disease or diabetes. Muscle weakness or muscle spasms. Fatigue, confusion, headache or vomiting. Read more

Related support groups: Peri-DS, Constipation, MiraLax, Magnesium Citrate, Dulcolax, Constipation - Chronic, Suprep, Lactulose, Polyethylene Glycol 3350, Metamucil, Milk of Magnesia, Fleet Enema, Bisacodyl, MoviPrep, Epsom Salt, Constipation - Acute, Senokot, Senna, Colace, Docusate

DNA May Affect What Bugs Reside in Your Gut

Posted 11 May 2016 by Drugs.com

WEDNESDAY, May 11, 2016 – At least some of the microbes that live in your gut may be influenced by your genes, a new study finds. "We set out to find out about human genes that are implicated in the regulation of the gut microbiome, and we found some that are," said senior study author Ruth Ley, an associate professor in the department of microbiology at Cornell University, in Ithaca, N.Y. For example, the researchers found a link between the LCT gene – involved in making the enzyme that helps the body digest dairy products – and a type of microorganism called Bifidobacterium, which is commonly used in probiotics. "Based on our research, we identified more than a dozen microbes with known links to health that are heritable," Ley said. "These microorganisms are environmentally acquired, but the genome also plays a part – by determining which microorganisms are more dominant than ... Read more

Related support groups: Diarrhea, Constipation, Gas, Gastrointestinal Disorders, Duodenitis/Gastritis, VSL#3, Probiotic Formula, Florajen3, Bifidobacterium Infantis, Healthy Colon, Align, VSL#3 DS, Provella, Gastric Motility Disorder, VLS#3, Bifidobacterium Infantis/lactobacillus Acidophilus, ReZyst IM

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Constipation - Chronic, Constipation - Acute, Constipation - Drug Induced, Opioid-Induced Constipation, Fecal Impaction, Chronic Idiopathic Constipation, Gastrointestinal Disorders

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