Oxyto-Sure (Canada)

This page contains information on Oxyto-Sure for veterinary use.
The information provided typically includes the following:
  • Oxyto-Sure Indications
  • Warnings and cautions for Oxyto-Sure
  • Direction and dosage information for Oxyto-Sure


This treatment applies to the following species:
Manufacturer: Vétoquinol

Oxytocin Injection USP


DIN 00052124

Veterinary Use Only

Active Ingredient

Oxytocin synthetic

20 I.U./mL



5 mg/mL

General Information:

Oxytocin is a posterior pituitary hormone. It acts directly on the smooth muscle of the uterus to produce rythmic contractions. Oxytocin is also closely related to the let down of milk.

Oxyto-Sure Indications

Oxyto-Sure™ can be used as an aid in the management of the following conditions in ewes, sows, cows, mares, bitches and cats.

1. To induce labor.

2. To accelerate the process of normal parturition.

3. Dystocia due to uterine inertia.

4. Post operative contraction of the uterus following caesarian section and the control of uterine haemorrhage.

5. Prolapsed uterus.

6. Postpartum evacuation of uterine debris.

7. Initiation of lactation following parturition.

8. Uncomplicated agalactia in sows.

9. Evacuation, debridement and drainage in cases of acute and chronic mastitis.

10. Agalactia in heifers and cows with extreme oedema of the udder.

Dosage and Administration

For obstetrical use, Oxyto-Sure™ may be administered intravenously, intramuscularly or subcutaneously, under aseptic conditions as indicated. The following dosages are recommended and may be repeated as needed:


1.5-2.5 mL (30-50 oxytocin units)


1.5-2.5 mL (30-50 oxytocin units)


2.5-5.0 mL (50-100 oxytocin units)


2.5-5.0 mL (50-100 oxytocin units)


0.25-1.50 mL (5-30 oxytocin units)


0.25-0.50 mL (5-10 oxytocin units)

To stimulate milk let down, Oxyto-Sure™ may be administered intravenously, intramuscularly or subcutaneously, under aseptic conditions as indicated. The following dosage is recommended and may be repeated as needed:


0.5-1.0 mL (10-20 oxytocin units)


0.25-1.0 mL (5-20 oxytocin units)

For rapidity of action and maximum effectiveness in mastitis treatment, the intravenous route is recommended. Oxytocin is more effective when administered intravenously as compared to other routes.


1.0-2.0 mL (20-40 oxytocin units)


Do not use in early stages of labour where the cervix is not fully relaxed, in presence of a mechanical obstruction (gross fetal deformities, malpresentation) or other factors predisposing to uterine rupture. Do not use in animals with impaired cardiac or renal function.

Oxyto-Sure Caution

This drug should be administered with caution. For prepartum usage, full relaxation of the cervix should be accomplished either naturally or by administration of estrogen prior to oxytocin therapy. Likewise, it may be desirable following parturition, to resensitize the uterus to oxytocin by the administration of estrogen 8 to 24 hours prior to oxytocin therapy. Excessive dosage may cause spasm of coronary arteries and high blood pressure.


Treated animals must not be slaughtered for use in food for at least 3 days after the latest treatment with this drug. Milk taken from treated animals during treatment and within 24 hours after the latest treatment must not be used as food. When this drug is administered intramuscularly to dairy cattle at a dose of up to 20 I.U. (1 mL), no milk withholding time is required.

Storage Conditions:

Store between 2 °C and 8 °C. Keep from freezing.


100 mL vials.

Vétoquinol N.-A. Inc., 2000, ch. Georges, Lavaltrie, QC, CANADA J5T 3S5




100 mL



NAC No.: 12342534

Commercial Division

Telephone:   450-586-2252
Order Desk:   800-363-1700
Fax:   450-586-4649
Website:   www.vetoquinol.ca
Email:   info@vetoquinol.ca
Every effort has been made to ensure the accuracy of the Oxyto-Sure information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert.

Copyright © 2015 North American Compendiums. Updated: 2015-04-03