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Vigamox Side Effects

Generic Name: moxifloxacin ophthalmic

Note: This page contains side effects data for the generic drug moxifloxacin ophthalmic. It is possible that some of the dosage forms included below may not apply to the brand name Vigamox.

For the Consumer

Applies to moxifloxacin ophthalmic: ophthalmic solution

As well as its needed effects, moxifloxacin ophthalmic (the active ingredient contained in Vigamox) may cause unwanted side effects that require medical attention.

Severity: Major

If any of the following side effects occur while taking moxifloxacin ophthalmic, check with your doctor immediately:

Incidence not known
  • Fainting or loss of consciousness
  • fast or irregular breathing
  • itching
  • skin rash
  • swelling of the eyes or eyelids
  • tightness in the chest or wheezing
  • trouble with breathing

Severity: Minor

Some moxifloxacin ophthalmic side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common
  • Burning, dry, or itching eyes
  • change in vision
  • decreased vision
  • dry eye
  • excessive tearing
  • eye discharge
  • itching of the eye
  • pain in the eye
  • red, sore eyes
  • redness of the eye
  • swelling of the eye, eyelid, or inner lining of the eyelid
  • tearing
Less common
  • Body aches or pain
  • congestion
  • cough or hoarseness
  • decreased hearing
  • dryness or soreness of the throat
  • fever or chills
  • general body discomfort
  • lower back or side pain
  • painful or difficult urination
  • rash
  • rubbing or pulling of the ears (in children)
  • runny nose
  • sore throat
  • tender, swollen glands in the neck
  • trouble with swallowing
  • voice changes
  • vomiting and diarrhea (in infants)

For Healthcare Professionals

Applies to moxifloxacin ophthalmic: ophthalmic solution

General

The most common side effects were eye irritation and eye pain.

Ocular

Common (1% to 10%): Conjunctivitis, decreased visual acuity, dry eye, keratitis, ocular discomfort, ocular hyperemia, ocular pain, ocular pruritus, subconjunctival hemorrhage, tearing, eye irritation, eye pain
Uncommon (0.1% to 1%): Punctuate keratitis, eye pruritus, conjunctival hemorrhage, eyelid edema
Rare (less than 0.1%): Corneal epithelium defect, corneal disorder, blepharitis, eye swelling, conjunctival edema, blurred vision, asthenopia, erythema of eyelid
Frequency not reported: Endophthalmitis, ulcerative keratitis, corneal erosion, corneal abrasion, intraocular pressure increased, corneal opacity, corneal infiltrates, corneal deposits, eye allergy, corneal edema, photophobia, lacrimation increased, eye discharge, foreign body sensation in eyes, corneal staining, eyelid disorder, abnormal sensation in eye[Ref]

Respiratory

Common (1% to 10%): Increased cough, pharyngitis, rhinitis
Rare (less than 0.1%): Nasal discomfort, pharyngolaryngeal pain, sensation of foreign body (throat)
Frequency not reported: Dyspnea[Ref]

Dermatologic

Common (1% to 10%): Rash
Frequency not reported: Erythema, pruritus, urticaria[Ref]

Other

Common (1% to 10%): Otitis media, fever/pyrexia, infection[Ref]

Nervous system

Uncommon (0.1% to 1%): Dysgeusia, headache
Rare (less than 0.1%): Paresthesia
Frequency not reported: Dizziness[Ref]

Gastrointestinal

Rare (less than 0.1%): Vomiting
Frequency not reported: Nausea[Ref]

Hematologic

Rare (less than 0.1%): Decreased hemoglobin[Ref]

Hepatic

Rare (less than 0.1%): Increased ALT, increased GGT[Ref]

Hypersensitivity

Serious and occasionally fatal hypersensitivity (anaphylactic) reactions (some after first dose) have been reported with systemic quinolones.[Ref]

Frequency not reported: Hypersensitivity

Systemic quinolones:
-Frequency not reported: Hypersensitivity (anaphylactic) reactions[Ref]

Cardiovascular

Frequency not reported: Palpitations[Ref]

Musculoskeletal

Systemic fluoroquinolones:
-Frequency not reported: Tendon ruptures[Ref]

Ruptures of the shoulder, hand, Achilles, or other tendons (requiring surgical repair or resulting in prolonged disability) have been reported with systemic fluoroquinolones. Risk of such ruptures may be increased in patients using concomitant corticosteroids, especially geriatric patients and in tendons under high stress (including the Achilles tendon).[Ref]

References

1. "Product Information. Moxeza (moxifloxacin ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.

2. "Product Information. Vigamox (moxifloxacin ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

It is possible that some side effects of Vigamox may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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