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Oxybutynin Side Effects

Medically reviewed by Drugs.com. Last updated on Mar 26, 2024.

Applies to oxybutynin: oral syrup, oral tablet, oral tablet extended release.

Other dosage forms:

Common side effects of oxybutynin

Some side effects of oxybutynin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • acid or sour stomach
  • belching
  • decreased sweating
  • diarrhea
  • difficulty having a bowel movement (stool)
  • drowsiness
  • dryness of the eyes, mouth, nose, or throat
  • heartburn
  • indigestion
  • runny nose
  • stomach discomfort, upset, or pain

Less common or rare

  • blurred vision
  • decreased flow of breast milk
  • decreased sexual ability
  • difficulty in swallowing
  • feeling of warmth or heat
  • headache
  • increased sensitivity of the eyes to light
  • nausea or vomiting
  • trouble with sleeping
  • unusual tiredness or weakness

Incidence not known

- Observed during clinical practice with oxybutynin; estimates of frequency cannot be determined
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • decreased interest in sexual intercourse
  • inability to have or keep an erection
  • loss in sexual ability, desire, drive, or performance
  • rapid weight gain
  • tingling of the hands or feet
  • unusual weight gain or loss

Serious side effects of oxybutynin

Along with its needed effects, oxybutynin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking oxybutynin:

Rare

  • eye pain
  • skin rash or hives

Get emergency help immediately if any of the following symptoms of overdose occur while taking oxybutynin:

Symptoms of overdose

For healthcare professionals

Applies to oxybutynin: oral solution, oral syrup, oral tablet, oral tablet extended release, transdermal film extended release, transdermal gel.

General

The most common (incidence 5% or greater) adverse reactions were dry mouth, constipation, diarrhea, headache, somnolence, and dizziness.[Ref]

Cardiovascular

Dermatologic

Endocrine

Gastrointestinal

Hypersensitivity

Genitourinary

Immunologic

Local

Metabolic

Musculoskeletal

Nervous system

Ocular

Other

Psychiatric

Respiratory

Other

Concomitant use of oxybutynin with carbamazepine and dantrolene has been associated with adverse events suggestive of carbamazepine toxicity, such as vomiting, drowsiness, confusion, unsteadiness, slurred speech, and nystagmus.

References

1. (2001) "Product Information. Ditropan (oxybutynin)." Hoechst Marion Roussel

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

3. Pharmaceutical Society of Australia (2006) APPGuide online. Australian prescription products guide online. http://www.appco.com.au/appguide/default.asp

Further information

Oxybutynin side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.