Menotropins Side Effects

Some side effects of menotropins may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to menotropins: intramuscular, subcutaneous injection

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abdominal pain; back pain; breast enlargement; chills; dizziness; fever; flu-like symptoms; flushing; general body discomfort; headache; menstrual changes; muscle or joint pain; pain or rash at the injection site.

Seek medical attention right away if any of these SEVERE side effects occur while taking menotropins:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abdominal bloating; changes in speech or vision; chest pain; decreased urination; diarrhea; fast heartbeat; nausea; one-sided weakness; severe abdominal pain; severe headache; shortness of breath; sudden leg pain; vomiting; weakness; weight gain; yellowing of the skin or eyes.

For Healthcare Professionals

Applies to menotropins: injectable powder for injection, intramuscular powder for injection, subcutaneous powder for injection


Local side effects have included injection site edema and injection site reaction.


Genitourinary side effects have included Ovarian Hyperstimulation Syndrome (OHSS), vaginal hemorrhage, ovarian disease, ectopic pregnancy, pelvic pain, uterine spasm, and breast tenderness.


Gastrointestinal side effects have included nausea, vomiting, diarrhea, abdominal cramping, abdominal pain, abdominal fullness, constipation, and enlarged abdomen.

Nervous system

Nervous system side effects have included headache, malaise, and dizziness.


Respiratory side effects have included dyspnea and increased cough.


General side effects have included infection, back pain, and flu syndrome.


Endocrine side effects have included elevated estradiol levels.

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