Didrex Side Effects

Generic name: benzphetamine

Note: This document contains side effect information about benzphetamine. Some of the dosage forms listed on this page may not apply to the brand name Didrex.

Some side effects of Didrex may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to benzphetamine: oral tablet

Get emergency medical help if you have any of these signs of an allergic reaction while taking benzphetamine (the active ingredient contained in Didrex) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking benzphetamine and call your doctor at once if you have a serious side effect such as:

• feeling short of breath, even with mild exertion;

• chest pain, feeling like you might pass out;

• swelling in your ankles or feet;

• pounding heartbeats or fluttering in your chest;

• confusion or irritability, unusual thoughts or behavior; or

• dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects of benzphetamine may include:

• feeling restless or hyperactive;

• headache, dizziness, tremors;

• sleep problems (insomnia);

• increased sweating;

• dry mouth or an unpleasant taste in your mouth;

• nausea, diarrhea upset stomach; or

• skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to benzphetamine: oral tablet

Cardiovascular

Cardiovascular side effects have included palpitation, tachycardia, and elevation of blood pressure. Isolated cases of cardiomyopathy and ischemic cardiac events have been reported in association with chronic amphetamine use. Valvular heart disease associated with the use of some anorectic agents such as fenfluramine and dexfenfluramine (both independently and especially when used in combination with other anorectic drugs) has been reported; however, no cases of this valvulopathy have been reported when benzphetamine (the active ingredient contained in Didrex) has been used alone.

Nervous system

Nervous system side effects have included restlessness, overstimulation, insomnia, dizziness, tremor, sweating, and headache.

Psychiatric

Psychiatric side effects have included depression following withdrawal of the drug and, rare instances of psychotic episodes.

Gastrointestinal

Gastrointestinal side effects have included nausea, diarrhea, unpleasant taste, dry mouth, and other gastrointestinal disturbances.

Genitourinary

Genitourinary side effects have included changes in libido.

Hypersensitivity

Hypersensitivity side effects have included urticaria and other allergic reactions involving the skin.

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