Dicyclomine Side Effects

Brand Names: Bentyl

Please note - some side effects for Dicyclomine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of Dicyclomine - for the Consumer

Dicyclomine

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Dicyclomine:

Blurred vision; constipation; decreased sweating; difficulty sleeping; dizziness; drowsiness; dry mouth; headache; lightheadedness; loss of taste; nausea; nervousness.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; confusion; diarrhea; difficulty focusing your eyes; difficulty moving; difficulty speaking; difficulty urinating; disorientation; exaggerated sense of well-being; fainting; hallucinations; pounding in the chest; rapid heartbeat; short-term memory loss; unusual weakness; vomiting.

Dicyclomine Capsules

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Dicyclomine Capsules:

Blurred vision; constipation; decreased sweating; difficulty sleeping; dizziness; drowsiness; dry mouth; headache; lightheadedness; loss of taste; nausea; nervousness.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; confusion; diarrhea; difficulty focusing your eyes; difficulty moving; difficulty speaking; difficulty urinating; disorientation; exaggerated sense of well-being; fainting; hallucinations; pounding in the chest, rapid heartbeat; short-term memory loss; unusual weakness; vomiting.

Dicyclomine Syrup

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Dicyclomine Syrup:

Blurred vision; constipation; decreased sweating; difficulty sleeping; dizziness; drowsiness; dry mouth; headache; lightheadedness; loss of taste; nausea; nervousness.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; confusion; diarrhea; difficulty focusing your eyes; difficulty moving; difficulty speaking; difficulty urinating; disorientation; exaggerated sense of well-being; fainting; hallucinations; pounding in the chest; rapid heartbeat; short-term memory loss; unusual weakness; vomiting.

Dicyclomine Side Effects - for the Professional

Dicyclomine

Controlled clinical trials have provided frequency information for reported adverse effects of Dicyclomine hydrochloride listed in a decreasing order of frequency.

Not all of the following adverse reactions have been reported with Dicyclomine hydrochloride. Adverse reactions are included here that have been reported for pharmacologically similar drugs with anticholinergic/antispasmodic action.

Gastrointestinal: dry mouth, nausea, vomiting, constipation. bloated feeling, abdominal pain, taste loss, anorexia.

Central Nervous System: dizziness, lightheadedness, tingling, headache, drowsiness, weakness, nervousness, numbness, mental confusion and/or excitement (especially in elderly persons), dyskinesia, lethargy, syncope, speech disturbance, insomnia.

Ophthalmologic: blurred vision, diplopia, mydriasis, cycloplegia, increased ocular tension

Dermatologic/Allergic: rash, urticaria, itching, and other dermal manifestations; severe allergic reaction or drug idiosyncrasies including anaphylaxis.

Genitourinary: urinary hesitancy, urinary retention

Cardiovascular: tachycardia. palpitations

Respiratory: Dyspnea, apnea, asphyxia

Other: decreased sweating, nasal stuffiness or congestion, sneezing, throat congestion, impotence, suppression of lactation

Dicyclomine Injection

Controlled clinical trials have provided frequency information for reported adverse effects of Dicyclomine hydrochloride listed in a decreasing order of frequency.

Not all of the following adverse reactions have been reported with Dicyclomine hydrochloride. Adverse reactions are included here that have been reported for pharmacologically similar drugs with anticholinergic/antispasmodic action.

Gastrointestinal: dry mouth, nausea, vomiting, constipation, bloated feeling, abdominal pain, taste loss, anorexia

Central Nervous System: dizziness, light-headedness, tingling, headache, drowsiness, weakness, nervousness, numbness, mental confusion and/or excitement (especially in elderly persons), dyskinesia, lethargy, syncope, speech disturbance, insomnia

Ophthalmologic: blurred vision, diplopia, mydriasis, cycloplegia, increased ocular tension

Dermatologic/Allergic: rash, urticaria, itching, and other dermal manifestation; severe allergic reaction or drug idiosyncrasies including anaphylaxis

Genitourinary: urinary hesitancy, urinary retention

Cardiovascular: tachycardia, palpitations

Respiratory: dyspnea, apnea, asphyxia

Other: decreased sweating, nasal stuffiness or congestion, sneezing, throat congestion, impotence, suppression of lactation

With the injectable form, there may be temporary sensation of light-headedness. Some local irritation and focal coagulation necrosis may occur following the I.M. injection of the drug.

Side Effects by Body System

Dermatologic

Dermatologic side effects commonly observed have included inhibition of exocrine sweat glands. This is usually not clinically significant except when perspiration becomes a major factor in body temperature control.

Gastrointestinal

Gastrointestinal side effects have been reported the most frequently. These have included the anticholinergic effects of dry mouth and mucous membranes. Other reported side effects have included delayed gastric emptying time, reduced gastric acid secretion, nausea, constipation, and gastroesophageal reflux.

Cardiovascular

Cardiovascular side effects have included tachycardia and palpitations from muscarinic blockade.

General

General side effects have included dicyclomine toxicity (anticholinergic side effects) which often presents with fever, tachycardia, agitation, and dry skin/mucous membranes.

Genitourinary

Genitourinary side effects have frequently included urinary retention as a result of the anticholinergic effects on the urinary sphincter and dose-related, and impotence in male patients.

Nervous system

Nervous system side effects have included lethargy and somnolence. Higher doses may be associated with mental confusion and/or excitement. The elderly appear to be more prone to the anticholinergic effects of dicyclomine on the CNS.

Ocular

Ocular side effects due to the anticholinergic activity of dicyclomine have included inhibition of the iris sphincter muscle (possibly resulting in mydriasis), follicular conjunctivitis, and inhibition of the ciliary muscle (which can produce blurred vision). All muscarinic antagonists can precipitate glaucoma.

Hypersensitivity

Hypersensitivity side effects have been reported rarely. These have included urticaria, pruritus, edema, hypotension, abdominal pain, tachypnea, and nausea and vomiting.

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