Armodafinil Side Effects
Not all side effects for armodafinil may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to armodafinil: oral tablet
In addition to its needed effects, some unwanted effects may be caused by armodafinil. In the event that any of these side effects do occur, they may require medical attention.
You should check with your doctor immediately if any of these side effects occur when taking armodafinil:Less common
- Blistering, burning, crusting, dryness, or flaking of the skin
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- difficult or labored breathing
- fast, irregular, pounding, or racing heartbeat or pulse
- frequent urination
- headache, severe and throbbing
- increased volume of pale, dilute urine
- itching, scaling, severe redness, soreness, or swelling of the skin
- shakiness in the legs, arms, hands, or feet
- shortness of breath
- tightness in the chest
- trembling or shaking of the hands or feet
If any of the following symptoms of overdose occur while taking armodafinil, get emergency help immediately:Symptoms of overdose
- blurred vision
- chest pain or discomfort
- confusion about identity, place, and time
- dry mouth
- lightheadedness, dizziness, or fainting
- pounding in the ears
- seeing, hearing, or feeling things that are not there
- slow heartbeat
- trouble sleeping
- unable to sleep
- unusual tiredness or weakness
Some of the side effects that can occur with armodafinil may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:Less common
- Acid or sour stomach
- difficulty having a bowel movement (stool)
- feeling sad or empty
- general feeling of discomfort or illness
- joint pain
- loss of appetite
- loss of interest or pleasure
- mood or mental changes
- muscle aches and pains
- runny nose
- sore throat
- stomach discomfort, upset, or pain
- trouble concentrating
- weight loss
For Healthcare Professionals
Applies to armodafinil: oral tablet
In general, armodafinil has been well tolerated and most side effects have been mild to moderate in severity.
Cardiovascular side effects have included palpitations (2%) and tachycardia (1%).
Gastrointestinal side effects have frequently included nausea (7%), diarrhea (4%), dry mouth (4%), dyspepsia (2%), and upper abdominal pain (2%). Constipation, vomiting, anorexia, decreased appetite, and loose stools have been reported in 1% of patients.
Nervous system side effects have included headache (17%), dizziness (5%), insomnia (5%), tremor (1%), migraine headache (1%), paresthesia (1%), and disturbance in attention (1%).
Other side effects have included fatigue (2%), thirst (1%), influenza-like illness (1%), fever (1%), and pain (1%).
Psychiatric side effects have included anxiety (4%), depression (2%), agitation (1%), nervousness (1%), and depressed mood (1%). Postmarketing adverse events associated with the use of modafinil have included aggression.
Genitourinary side effects have included polyuria (1%).
Respiratory side effects have included dyspnea (1%).
Dermatologic side effects have included rash (2%), contact dermatitis (1%), and hyperhydrosis (1%). Serious rash requiring hospitalization and discontinuation of treatment has been reported in adults in association with the use of modafinil and armodafinil.
Hematologic side effects include a single case of mild pancytopenia that resolved following discontinuation of armodafinil.
More about armodafinil
- Other brands: Nuvigil
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