Generic Name: naloxone (nah LOX own)
Brand Name: Evzio
What is Narcan (naloxone)?
Naloxone is an special narcotic drug that reverses the effects of other narcotic medicines.
Naloxone is used to reverse the effects of narcotic drugs used during surgery or to treat pain.
Naloxone may also be used to treat narcotic drug overdose or to diagnose narcotic drug addiction.
Naloxone may also be used for purposes not listed in this medication guide.
What is the most important information I should know about Narcan (naloxone)?
In an emergency situation it may not be possible before you are treated to tell your caregivers about your health conditions or if you are pregnant or breast feeding. Make sure any doctor caring for you afterward knows that you have received this medication.
What should I discuss with my health care provider before receiving Narcan (naloxone)?
You should not use this medicine if you are allergic to naloxone.
If possible before you receive naloxone, tell your doctor if you have:
a history of head injury or brain tumor; or
a history of drug or alcohol addiction.
FDA pregnancy category C. It is not known whether naloxone will harm an unborn baby. Tell your doctor if you are pregnant.
It is not known whether naloxone passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How is naloxone given?
Naloxone is injected into a muscle or under the skin, or into a vein through an IV. You will receive this injection in a clinic or hospital setting.
Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely while you are receiving naloxone. This will help your doctor determine how long to treat you with this medication.
What happens if I miss a dose?
Because you will receive naloxone in a clinical setting, you are not likely to miss a dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include seizure (convulsions), feeling light-headed, or fainting.
What should I avoid while using Narcan (naloxone)?
Naloxone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Drinking alcohol can increase certain side effects of naloxone.
Narcan (naloxone) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers right away if you have:
a light-headed feeling, like you might pass out;
slow heart rate, weak or shallow breathing;
anxiety, sweating, pale skin, severe shortness of breath, wheezing, gasping for breath, cough with foamy mucus, chest pain, fast or uneven heart rate; or
dangerously high blood pressure--severe headache, blurred vision, pounding in your neck or ears, nosebleed, anxiety, confusion, severe chest pain, shortness of breath, irregular heartbeats, seizure.
If you are being treated for narcotic drug addiction, naloxone may cause withdrawal symptoms such as:
nausea, vomiting, diarrhea, stomach pain;
fever, sweating, body aches, weakness, runny nose;
feeling nervous, restless, or irritable;
goosebumps, shivering; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Narcan (naloxone)?
If you are using any narcotic pain medicine, the pain-relieving effects of the narcotic will be reversed while you are also receiving naloxone.
Other drugs may interact with naloxone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
More about Narcan (naloxone)
- Other brands: Evzio
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about naloxone.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 3.03. Revision Date: 2014-08-16, 8:20:04 AM.