Ambien (zolpidem) Alcohol, Food & Lifestyle Interactions

There are 2 food and lifestyle interactions with Ambien (zolpidem) which include:

GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents. Use in combination may result in additive central nervous system depression and impairment of judgment, thinking, and psychomotor skills.

MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol. Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.

ADJUST DOSING INTERVAL: Administration of zolpidem with food may delay the onset of hypnotic effects. In 30 healthy subjects, administration of zolpidem 20 minutes after a meal resulted in decreased mean peak plasma drug concentration (Cmax) and area under the concentration-time curve (AUC) by 25% and 15%, respectively, compared to fasting. The time to reach peak plasma drug concentration (Tmax) was prolonged by 60%, from 1.4 to 2.2 hours.

MANAGEMENT: For faster sleep onset, zolpidem should not be administered with or immediately after a meal.

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Ambien (zolpidem) drug Interactions

There are 609 drug interactions with Ambien (zolpidem)

Ambien (zolpidem) disease Interactions

There are 6 disease interactions with Ambien (zolpidem) which include:

Alcohol Intox Drug Dependence Liver Disease

Depression Resp Depression Renal Dysfunction

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