Hydrocodone/ibuprofen Drug Interactions
Currently displaying 301 drugs known to have a major interaction with hydrocodone / ibuprofen.
- 301 major drug interactions
- 526 moderate drug interactions
- 11 minor drug interactions
Major interactions with hydrocodone / ibuprofen
Note: Showing generic names only.
A
- abiraterone
- acalabrutinib
- acetylcarbromal
- adefovir
- alprazolam
- alvimopan
- aminoglutethimide
- aminolevulinic acid
- amiodarone
- amobarbital
- amprenavir
- anisindione
- apalutamide
- apixaban
- aprepitant
- ardeparin
- aripiprazole
- armodafinil
- asenapine
- aspirin
- atazanavir
- avapritinib
B
- baclofen
- belzutifan
- berotralstat
- betrixaban
- boceprevir
- bosentan
- botulism immune globulin
- brexanolone
- brexpiprazole
- bromfenac
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cabozantinib
- cannabis
- carbamazepine
- cariprazine
- carisoprodol
- celecoxib
- cenobamate
- ceritinib
- chloral hydrate
- chloramphenicol
- chlordiazepoxide
- chlormezanone
- chlorphenesin
- chlorpromazine
- chlorzoxazone
- cidofovir
- cimetidine
- ciprofloxacin
- clarithromycin
- clobazam
- clofazimine
- clonazepam
- clorazepate
- clotrimazole
- clozapine
- cobicistat
- codeine
- conivaptan
- crizotinib
- cyclobenzaprine
- cytomegalovirus immune globulin
D
- dabigatran
- dabrafenib
- dalteparin
- danaparoid
- dantrolene
- daridorexant
- darunavir
- dasatinib
- deferasirox
- delavirdine
- desirudin
- dexamethasone
- dezocine
- diatrizoate
- diazepam
- diclofenac
- dicumarol
- diflunisal
- diltiazem
- dronedarone
- drotrecogin alfa
- duvelisib
E
- edoxaban
- efavirenz
- elagolix
- encorafenib
- enoxaparin
- enzalutamide
- erythromycin
- esketamine
- eslicarbazepine
- estazolam
- eszopiclone
- ethanol
- ethchlorvynol
- etodolac
- etravirine
- everolimus
F
- fedratinib
- fenoprofen
- fentanyl
- fexinidazole
- fluconazole
- fluphenazine
- flurazepam
- flurbiprofen
- fondaparinux
- fosamprenavir
- fosaprepitant
- fosphenytoin
- furazolidone
G
H
I
- ibritumomab
- ibrutinib
- idelalisib
- iloperidone
- imatinib
- immune globulin intravenous
- immune globulin intravenous and subcutaneous
- indinavir
- indomethacin
- inotersen
- iodamide
- iodine i 131 tositumomab
- iodipamide
- iodixanol
- iohexol
- iomeprol
- iopamidol
- iopromide
- iothalamate
- ioversol
- ioxaglate
- ioxilan
- isavuconazonium
- isocarboxazid
- itraconazole
- ivosidenib
K
L
- leflunomide
- lemborexant
- letermovir
- levoketoconazole
- levomethadyl acetate
- levorphanol
- linezolid
- lithium
- lomitapide
- lonafarnib
- lorazepam
- lorlatinib
- loxapine
- lumateperone
- lurasidone
M
- mavacamten
- meclofenamate
- mefenamic acid
- meloxicam
- meperidine
- mephobarbital
- meprobamate
- mesoridazine
- metaxalone
- methadone
- methocarbamol
- methotrexate
- methylene blue
- metrizamide
- mibefradil
- mifepristone
- mipomersen
- mitotane
- modafinil
- molindone
- morphine
- morphine liposomal
N
O
- olanzapine
- oliceridine
- olutasidenib
- omacetaxine
- orphenadrine
- oxaprozin
- oxazepam
- oxcarbazepine
- oxycodone
- oxymorphone
P
- paliperidone
- panobinostat
- paraldehyde
- pazopanib
- peanut allergen powder
- pentazocine
- pentobarbital
- perphenazine
- pexidartinib
- phenelzine
- phenobarbital
- phenylbutazone
- phenytoin
- pimavanserin
- pimozide
- piroxicam
- plasminogen, human
- ponatinib
- posaconazole
- prasugrel
- pregabalin
- primidone
- procarbazine
- promazine
- propiomazine
- propoxyphene
Q
R
- ramelteon
- ramucirumab
- ranolazine
- regorafenib
- remimazolam
- repotrectinib
- respiratory syncytial virus immune globulin
- rho (d) immune globulin
- ribociclib
- rifabutin
- rifampin
- rifapentine
- risperidone
- ritonavir
- rivaroxaban
- rofecoxib
S
- saquinavir
- secobarbital
- selegiline
- sirolimus
- sodium oxybate
- sotorasib
- st. john's wort
- stiripentol
- sulindac
- suvorexant
T
- tacrolimus
- tapentadol
- tasimelteon
- telaprevir
- telithromycin
- telotristat
- temazepam
- temsirolimus
- tenofovir alafenamide
- tenofovir disoproxil
- teriflunomide
- thioridazine
- thiothixene
- tinzaparin
- tizanidine
- tolmetin
- tositumomab
- tovorafenib
- tramadol
- tranylcypromine
- triazolam
- trifluoperazine
- triflupromazine
- troleandomycin
- tucatinib
V
W
Z
Hydrocodone/ibuprofen alcohol/food interactions
There are 3 alcohol/food interactions with hydrocodone / ibuprofen.
Hydrocodone/ibuprofen disease interactions
There are 29 disease interactions with hydrocodone / ibuprofen which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- PKU
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- anemia
- heart failure
- hepatotoxicity
- hyperkalemia
- hypertension
- platelet aggregation inhibition
- arrhythmias
- biliary tract disease
More about hydrocodone / ibuprofen
- hydrocodone/ibuprofen consumer information
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (74)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: narcotic analgesic combinations
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Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.