Alogliptin Dosage

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Diabetes Type 2

25 mg once daily

Comments: Take with or without food

Renal Dose Adjustments

Mild renal dysfunction (CrCl greater than or equal to 60 mL/min): No adjustment recommended
Moderate renal dysfunction (CrCl greater than or equal to 30 mL/min to less than 60 mL/min): 12.5 mg once daily
Severe renal dysfunction (CrCl greater than or equal to 15 mL/min to less than 30 mL/min) and end-stage renal disease (ESRD) (CrCl less than 15 mL/min or requiring hemodialysis): 6.25 mg once daily

Comments: Administer without regard to the timing of dialysis. Data not available for patients undergoing peritoneal dialysis.

Liver Dose Adjustments

Mild to moderate liver dysfunction (Child-Pugh Grade A and B): No adjustment recommended
Severe liver dysfunction (Child-Pugh C): Data not available. Use caution when administering to patients with liver disease

Precautions

Consult WARNINGS section for dosing related precautions

Dialysis

Minimally dialyzable (7% drug removal over 3 hours) and no dose adjustment guidelines have been reported.

Other Comments

Administration advice: Take with or without food.

Patient advice: Hypoglycemia can occur when used with insulin or an insulin secretagogue.

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